Bridgeway Center, Inc. - News - Another Eli Lilly Drug... -
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Published on: 4/1/2003
Last Visited: 1/2/2004
By combining them, "there's a synergy effect beyond what you expect" from taking the drugs separately, said Dr. Robert W. Baker, associate medical director for U.S. neurosciences at Lilly.
He said Lilly studies show Symbyax is effective in easing symptoms of depression in up to 60 percent of bipolar patients without pushing them into mania, which happens as much as half the time when antidepressants alone are given.
In one eight-week Lilly study, only 5 percent of patients taking Symbyax for bipolar depression swung into the manic phase, Baker said.
When effective, Symbyax "lifts the depression and gets to the middle zone you're shooting for rather than breaking through into mania," he said.
Zyprexa, Lilly's current best-seller, is approved for schizophrenia and acute mania in bipolar disorder.