Dr. Wes Ashford This is Me

Education

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1. 1. neurotezinc.neurotez.com

   neurotezinc.neurotez.com/gpage - [Cached]

   Published on: 2/20/2008   Last Visited: 2/20/2008

   Dr. Wes Ashford became the chief medical officer of Neurotez in 2007. Dr. Ashford is Senior Research Scientist at the Stanford / VA Alzheimer Center. He is involved in the coordination of several clinical trials sponsored by the NIH and corporations. He previously served as the Lead Investigator in the PET scan project and the first double-blind study of a cholinesterase inhibitor to treat Alzheimer's Disease among others. Dr. Ashford is leading an international group of scientists to advocate for wide-spread screening for dementia and Alzheimer's disease. He has been developing dementia measurement tools and screening tests that can be used for early detection of this prevalent condition and applied to the rapid and precise assessment of the efficacy of experimental treatments. Prior to joining Stanford/ VA in 2003, he served as faculty at Southern Illinois University, the University of California, Davis, and the University of Kentucky, reaching the rank of tenured Associate Professor. He also directed the Geriatric Psychiatry Clinic at UCLA between 1980 and 1985 and the Lexington VAMC Memory Disorders Clinic.
   
   His seminal work includes application of the basic physical principle of Relative-Time to dementia severity measurement, extended to the fields of Alzheimer's disease and genetics. In addition, he originally proposed the now widely accepted theory of neuroplasticity as the vulnerable factor in Alzheimer's disease. In 1989 he conceived the first application of Modern Test Theory in the field of Medicine using Item Characteristic Curve analysis to explain the properties of a cognitive test that has been popular for measuring dementia severity. Earlier, his PhD dissertation was a finalist for the Donald B. Lindsley Prize of the Society for Neuroscience, as the first to show physiologically how the brain uses massive parallel distributed processing to analyze information.
   
   Dr. Ashford attended UCLA attaining an M.D. degree, a Ph.D. in Neuroscience and finishing his psychiatry residency. He obtained his BA from the University of California, Berkeley.

2. 2. Cognitive Labs Blog: 12.03.2004

   blog.cognitivelabs.com/2004_12 - [Cached]

   Published on: 12/3/2004   Last Visited: 10/1/2006

   I forgot to mention that Wes technically could not classify as a high tech hunk, not being in technology but has a very remarkable resemblance to Stephen Speilberg.
   ...
   Another new member of the team is Dr. Wes Ashford, senior scientist at the Stanford/VA NIH Alzheimer's Center, whose expertise is neuropsychological testing and the early incidence of Alzheimer's Disease.
   
   Wes has a B.S. from UC-Berkeley, M.D. from UCLA-Geffen School of Medicine, and a Ph.D. in Neuroscience, also from UCLA.
   
   Here is a summary of Dr. Ashford's AlzForum' presentation on genetic risk factors for Alzheimer's Disease:
   ...
   The specific Gompertz parameters underlying AD are not understood, but even so, it is clear that ApoE genotype changes this curve, Ashford said.
   ...
   ApoE exerts its main effect by influencing when people get AD, Ashford said. In a clinic population, the E4/4 genotype reduces the mean age of onset to 68 from 74 in E3/3 carriers.
   
   Environmental factors and nonspecific genes also play a role in determining AD risk and may, in fact, have a relatively greater effect in very old age (see also Silverman et al., 2003). Ashford suggested that the E2 and E3 alleles, which evolved from the ancestral E4, better support the remodeling of dendrites and minimize neuronal stress over time (see also Live Discussion).
   ...
   The cognitive labs brain trust continues to expand as Dr. Elan Amir and Dr. Wes Ashford have joined our management advisory team.

3. 3. Cognitive Labs - Home Base for Cognitive Labs: Check, Monitor, and Preserve Your Memory and Cognition

   www.cognitivelabs.com/people.h - [Cached]

   Published on: 5/8/2004   Last Visited: 12/8/2005

   · Wes Ashford, M.D., Ph.D.
   ...
   Dr. Wes Ashford, M.D., Ph.D., Dr. Ashford is Senior Scientist at the Stanford-VA Alzheimer's Center, Palo Alto, CA. Dr. Ashford is an authority on Alzheimer's Disease, MCI, neuropsych. testing with more than 50 scientific publications on Alzheimer's, Mild Cognitive Impairment, genetic factors in Alzheimer's and testing methodologies. Dr. Ashford is a Board Member of the Northern California Alzheimer's Association. Dr. Ashford's training includes a B.S. from UC-Berkeley; an M.D. from the David Geffen School of Medicine at UCLA; and a Ph.D. in Neuroscience from UCLA, where he set up the Alzheimer's Lab.