Dr. Richard J. Albertini This is Me

Education

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1. 1. BioMosaics Home

   www.biomosaics.com/Management. - [Cached]

   Published on: 7/16/2008   Last Visited: 7/16/2008

   Richard J. Albertini, MD, PhD, Executive Vice President of Research
   
   Dr. Albertini is Emeritus Professor of Medicine at the University of Vermont, former Director of the Vermont Cancer Center.He served as President of the Environmental Mutagen Society from 1983-84.Dr. Albertini received the Alexander Hollaender Award of the Environmental Mutagen Society in 1990 and the St. George Medal of the American Cancer Society that same year.

2. 2. www.vermontcancer.org

   www.vermontcancer.org/index.ph - [Cached]

   Published on: 7/21/2008   Last Visited: 7/21/2008

   Richard Albertini
   
   Vermont Cancer Center - Richard Albertini, MD, PhD
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   Richard Albertini, MD, PhD
   
   Research Professor of PathologyResearch Program: Genome Stability & ExpressionVCC Membership Level: Member Scientist
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   Dr. Albertini received his MD from the University of Wisconsin Medical School in 1963 and his PhD from the Department of Medical Genetics at the University of Wisconsin in 1972.Dr. Albertini joined the faculty of the UVM College of Medicine in 1974.In addition to his appointment in pathology, he is an adjunct member of the Department of Microbiology and Molecular Genetics.
   
   Research
   
   Dr. Albertini's research focuses on human somatic cell mutations.Somatic mutations arise in vivo in humans and can be measured and analyzed with precision.At the fundamental level, these mutations provide probes for investigating basic mutagenic mechanisms while, at the practical level, they provide biomarkers for assessing environmental health hazards.An important aspect of somatic mutations is their role in human diseases such as cancer.
   
   The primary interest of Dr. Albertini's laboratory is somatic mutations that arise in vivo in human T-lymphocytes.They have developed a method for quantitating these events in the "reporter gene" hypoxanthine-guanine phosphoribosyltransferase (hprt) and have used it in a variety of human studies.One kind of study measures mutation induction in vivo in individuals exposed to environmental mutagens and carcinogens as a biomarker for assessing environmental cancer risks.
   
   Mutant T-cells arising in vivo in humans can be isolated and characterized in vitro.Therefore, Dr. Albertini's laboratory has a major commitment in determining molecular mutational spectra.This has proved fruitful both for establishing basic mutagenic mechanisms and as a means for assessing the specificity of environmental mutagens/carcinogens.
   
   Other studies of in vivo T-cell hprt mutations have revealed an unanticipated level of complexity.
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   Dr. Albertini's mutational studies in T-cells, therefore, include molecular analyses of TcR genes.Also, he is developing additional reporter genes.His laboratory has a concentrated effort in identifying individual susceptibiity to environmental mutagens and carcinogens as part of our overall interest in genetic predisposition to cancer.

3. 3. www.ems-us.org

   www.ems-us.org/who_we_are/hist - [Cached]

   Published on: 2/20/2008   Last Visited: 5/23/2008

   Dick Albertini
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   Dick Albertini