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This profile was last updated on 6/22/12  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Warren Hoeffler

Wrong Dr. Warren Hoeffler?
Email: w***@***.com
 
Background

Employment History

  • President and Chief Executive Officer
    Xgene Corporation
  • Teacher
    Dominican University
  • Clinical Professor At Department of Dermatology
    Stanford University Medical School
  • Assistant Professor of Dermatology
    Stanford University Medical School
  • Faculty Member
    Stanford University Medical School
  • Postdoc and Levinson Lab
    Genentech , Inc.

Board Memberships and Affiliations

Education

  • Ph.D.
    Washington University
  • Dermatology Department
    Stanford University Medical School
  • A.B.
    Columbia University
20 Total References
Web References
Warren Hoeffler, ...
www.sec.gov, 22 June 2012 [cached]
Warren Hoeffler, Ph.D.
...
Warren Hoeffler, Ph.D. has served as President and Chief Executive Officer of Xgene Corporation, located at 480 Gate 5 Road, Sausalito, California since he founded the company in July 1998. The company focuses on technology to assemble primary cell cultures into larger tissue and organ components, and the storage of cell assemblies using their unique cryotronic freezing method. With its technology established, Xgene seeks licensing opportunities. The company's operations were transferred to a company-sponsored laboratory at Dominican University in San Rafael California, where Dr. Hoeffler also teaches as an adjunct faculty member. Dr. Hoeffler previously joined Stanford University Medical School in the Dermatology Department in 1992 and served as assistant professor from 1995 until 1998. From 1988 to 1992 he trained as a postdoctoral fellow in the laboratory of Dr. Arthur D. Levinson at Genentech, Inc., currently a division of Hoffmann-La Roche. Dr. Hoeffler holds a Ph.D. from Washington University and an A.B. from Columbia University. He holds U.S. and European patents on technology to assemble organs from primary cell cultures, and U.S. and Japanese patents on gene expression, with other patents pending. Dr. Hoeffler brings to the Board his extensive experience in business, medicine, and biotechnology.
...
Warren Hoeffler
Xgene Corporation - CoActive
www.coactivepr.com, 30 Nov 2009 [cached]
Warren Hoeffler, President & CEO, Xgene Corporation
History: Almost by accident, Warren Hoeffler, Clinical Professor at Stanford Medical School's Department of Dermatology, discovered a new method of growing bio-engineered skin while conducting a routine experiment. Realizing the promise that bio-engineered skin could one day offer burn victims and the viability for an alternative to expensive and controversial animal testing, Dr. Hoeffler founded Xgene Corporation in 1998.
Warren Hoeffler, ...
www.sec.gov, 1 June 2012 [cached]
Warren Hoeffler, Ph.D.
Since he founded it in July 1998, Dr. Hoeffler, age 56, has served as President and Chief Executive Officer of Xgene Corporation in Sausalito, California. The company focuses on technology to assemble primary cell cultures into larger tissue and organ components, and the storage of cell assemblies using their unique cryotronic freezing method. The company sponsors a laboratory at Dominican University in San Rafael California, where Dr. Hoeffler also teaches as an adjunct faculty member. Dr. Hoeffler trained as a postdoctoral fellow in the laboratory of Dr. Arthur D. Levinson at Genentech, Inc., currently a division of Hoffmann-La Roche.
...
Dr. Hoeffler holds a Ph.D. from Washington University and an A.B. from Columbia University. He holds U.S. and European patents on technology to assemble organs from primary cell cultures, and U.S. and Japanese patents on gene expression, with other patents pending. Dr. Hoeffler brings to the Board his extensive experience in business, medicine, and biotechnology.
The Stockholders believe that satisfies the director independence requirements of The NASDAQ Stock Market. Dr. Hoeffler has consented in writing to being named in the proxy statement as a nominee and to serving as a director if elected. A copy of Dr. Hoeffler's consent is attached to this Notice.
Dr. Hoeffler's address is c/o XGene Corporation, 480 Gate 5 Road, Sausalito, California 94965.
Dr. Hoeffler is the beneficial owner of no shares of the Company's common stock.
Dr. Hoeffler has not effected any purchases or sales of securities of the Company during the past two years.
Dr. Hoeffler is not, nor within the past year was, a party to any contract, arrangements or understandings with any person with respect to any securities of the Company, including, but not limited to, joint ventures, loan or option arrangements, puts or calls, guarantees against loss or guarantees of profit, division of losses or profits, or the giving or withholding of proxies.
None of Dr. Hoeffler, any member of his immediate family nor any of his associates was a party to any transaction, or series of similar transactions, since December 1, 2009, or is a party to any currently proposed transaction, or series of similar transactions, to which the Company or any of its subsidiaries was or is to be a party, in which the amount exceeds the lesser of $120,000 or 1% of the average of the Company's total assets at year end for the last 2 completed fiscal years.
None of Dr. Hoeffler nor any of his associates has any arrangement or understanding with any person with respect to any future employment by the Company or any of its affiliates, or with respect to any future transactions to which the Company or any of its affiliates will or may be a party.
No person, including Dr. Hoeffler, who is a party to an arrangement or understanding pursuant to which Dr. Hoeffler is proposed to be elected has a substantial interest, direct or indirect, by security holdings or otherwise, in any matter to be acted on at the Annual Meeting, aside from the election to serve as a director of the Company.
There are currently no material pending legal proceedings to which Dr. Hoeffler or any of his associates is a party adverse to the Company or any of its affiliates, or in which either Dr. Hoeffler or any of his associates has a material interest adverse to the Company or any of its affiliates.
Dr. Hoeffler has not had any business relationship that is required to be disclosed pursuant to Item 404(b) of Regulation S-K of the Securities Act of 1933, as amended.
Dr. Hoeffler does not have any family relationship, by blood, marriage or adoption, to any current director, executive officer or other affiliate of the Company or to any Nominee.
Dr. Hoeffler has not, during the past 10 years, been involved in any legal proceedings or involved in any other event described in Item 401(f) of Regulation S-K.
During the Company's last 2 fiscal years, no compensation or personal benefits (including, without limitation, those which would be required to be disclosed pursuant to Item 402 of Regulation S-K) were awarded to, earned by or paid to Dr. Hoeffler or any of his associates for any services rendered in any capacity to the Company or its subsidiaries or affiliates.
There is no arrangement and/or understanding between Dr. Hoeffler and any other person pursuant to which Dr. Hoeffler was or is to be selected as a director nominee for election as a director of the Company.
Dr. Hoeffler does not currently hold any position or office with the Company or any parent, subsidiary and/or affiliate thereof.
...
I, Warren Hoeffler, do hereby consent to serve as a director of Cryo-Cell International, Inc., a Delaware corporation, if nominated and elected to serve, and to be named in any required proxy statement, information statement, proxy card and/or other proxy soliciting materials.
May 27, 2012
/s/ Warren Hoeffler
...
Warren Hoeffler
CONSENT TO SERVE AS A DIRECTOR
The Scientist :: Scientist Login
www.the-scientist.com, 7 July 2002 [cached]
Senior author Warren K. Hoeffler, then an assistant professor of dermatology at Stanford University School of Medicine, developed a cell-sorting technology that enabled the researchers to obtain these results in the fibroblasts of a human "skin equivalent."Hoeffler is founder and president of the Burlingame, Calif.-based Xgene Corp., and has licensed the technology exclusively to Stanford University.The skin is cultured on the backs of mice in a cell slurry containing two human cell types: dermal fibroblasts, which form connective collagen fibers, and keratinocytes from the epidermis.The cell types then sort out, to reconstitute the dermis and stratified epidermis of human skin.
Hoeffler's company also has a patent pending on a method of growing skin in a culture dish in which a biopsy taken from a patient is disrupted, thus breaking the tissue into separate cells.The cells then sort into the proper layers through Xgene's technology and the reconstituted skin is then grafted onto the patient.Addition of telomerase to the cultured cells would extend their in vivo replicative life indefinitely.
...
Hoeffler believes his method will avoid the blistering and failure of the graft to "take" that plague composite skins.A major cause of graft failure is that the skin is grown on an inert scaffold, such as a biodegradable polymer, which creates a barrier between the cultured tissue and nutrients derived from the wound bed. "What we've started to do is construct the skin upside down," he explains.The epidermis is on the bottom, next to the scaffold.When the culture is ready for grafting, the skin is flipped over.The dermis is placed directly on the vascular bed, and the scaffolding on top becomes part of the wound dressing.
Sausalito's Xgene advances human tissue
www.northbaybusinessjournal.com, 5 June 2006 [cached]
Contact/title: Warren Hoeffler PhD
Founded: 1998
...
Led by former Stanford faculty member Warren Hoeffler, Ph.D, Xgene Corporation has patented a method of growing both the inner and outer layers of tissue that cover the human frame and organs.
"The interaction between the epidermal and mesenchymal layers is vital to the functionality of each part of the body, so the living cells are instructed to interact in similar ways at different locations," said Dr. Hoeffler.
...
"The advantage to testing on complex layers of human skin are obvious," said Dr. Hoeffler.
Although Xgene has generated several million dollars in sales, it spends the revenue just as quickly on further research.So far the company has stayed away from the venture capital community.
"We wanted to incubate our technology to maturity before being pushed to profitability," Dr. Hoeffler said.
May benefit from stem-cell program
He and his team have received grants from the National Institutes of Health, and may be indirectly on the receiving end of some of the $3 billion California has slated to spend on stem cell research.
That's because Xgene has just formed an agreement with Alameda-based Advanced Cell Technology, a stem cell company that recently relocated to California.Advanced Cell President Michael West, Ph.D, collaborated with Dr. Hoeffler at Stanford.
...
Dr. Hoeffler admits his research has been met with a certain amount of skepticism.
"Our insistence on regenerating complex tissues from cell slurries has been confusing to the non-scientific community, but then advances are often met with skepticism. 'Why to we need another source of light,' people asked Edison. 'Candles and gas lamps already do a great job.'
"Innovation begins in the dark, and ultimately some positive discoveries may come to light," he said.
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