Dr. Virginia BakerCHIPOLA BIOLOGY PROF WORKING ON MALARIA VACCINE -- Chipola College biology professor Dr. Virginia Baker is working with colleagues at Florida State University and the World Health Mission to unravel the mysteries hidden in the poor efficacy of the malaria vaccine. Dr. Baker
says, "In the field of malaria research, we are frequently confronted with the hopeful perspective that a malaria vaccine is eminent.Unfortunately, the development of such a vaccine has remained elusive, with factors of unknown origin undermining its success." Attempts to explain the ineffective immune response have been sought by Dr. Virginia Baker of Chipola College, and colleagues at FSU and World Health Mission.
While working in Nigeria, Dr. Baker
uncovered an unexpected autoimmune phenomenon found in children under the age of six.The impact of this find may lie in a novel discovery of an innate immune response never before identified in association with malaria.This autoimmune activity against double-stranded DNA may negate effective delivery of the vaccineâ€"which in many cases is based on a DNA adjuvant to mount an effective immune response.
After describing the discovery to researchers at Centers for Disease Control
in July, 2007, Dr. Baker
was invited to speak at The American Society of Tropical Medicine
& Hygiene Meeting in Philadelphia, November 3-8, 2007.In heated debates, the data was critiqued by researchers involved in the Bill Gates vaccination initiative and by international malaria research team members.
Cytokine-Associated Neutrophil Extracellular Traps in Plasmodium Falciparum Infected Children under the Age of Six, the title of the manuscript describing the novel immune response, was submitted by Dr. Baker
and colleagues to the MALARIA JOURNAL
, where it has recently been accepted for publication by peer review.The manuscript has claimed international attention and press as the long sought-after explanation for malaria vaccination failure.Invitations for Dr. Baker
to speak about the research are as far-reaching as Guangzhou, China. Dr. Baker
acknowledges support by Chipola College
to attend the international meeting in Philadelphia, as well as support to build a laboratory setting in which to engage students in the pursuit of research venues.