Prof Venugopal Nair
+44 (0)1635 577 356
Prof. Venugopal Nair obtained the Bachelors Degree in Veterinary & Animal Sciences from the Kerala Agricultural University, Trichur, India in 1976.
After obtaining a PhD in Veterinary Medicine from the Tamil Nadu Agricultural University, Chennai, India in 1987, he started his research career as a post-doctoral scientist at the Indian Institute of Science, Bangalore.
Dr. Nair joined Dr. Ernie Gould's group at the Institute of Virology & Environmental Microbiology, Oxford as postdoctoral research fellow in 1989, where he carried out extensive research until 1994 on the molecular biology of arthropod-borne flaviviruses.
moved to the Institute for Animal Health
in 1994 to join Dr. Jim Payne's group to work on avian oncogenic viruses.
Dr. Nair is the designated expert of the OIE (Office International des Epizooties) Reference Centre on Marek's disease and was the Chairman of the organizing committee of the 7th International Marek's Disease Symposium in Oxford in 2004.
He is also a Visiting Professor at Imperial College London since 2005, and is a member of the Board of Editors of Avian Pathology.
Prof. Nair became a Jenner Investigator in January 2007.
One of the aims of Dr. Nair's
research is to investigate the molecular mechanisms of for the continued increase in virulence.
In collaboration, with Prof. Andrew Read, University of Edinburgh
, Dr. Nair
is examining the role of vaccines in driving MDV virulence.
With an aim to unravel the molecular mechanisms of MDV-induced neoplastic transformation, Dr. Nair
group carries out in-depth analysis of the transcriptome, proteome and the interactome of MDV-transformed cells to understand the molecular pathways of oncogenesis.
group has established infectious bacterial artificial chromosome (BAC) clones of different MDV strains, which allow random or targeted mutagenesis to identify genes associated with pathogenicity.
More recently, Dr. Nair's
group has identified several herpesvirus-encoded microRNAs that have profound influence of the biology of these viruses.
Yao, Y., Zhao, Y., Xu, H., Smith, L. P.
, Lawrie, C. H., Sewer, A., Zavolan, M. & Nair
, V. (2007) Marek's disease virus type 2 (MDV-2)-encoded microRNAs show no sequence conservation to those encoded by MDV-1.
Stephen J. Spatz, Lawrence Petherbridge, Yuguang Zhao and Venugopal Nair (2007) Comparative full-length sequence analysis of oncogenic and vaccine (Rispens) strains of Marek's disease virus Journal of General Virology 88, 1080-1096.
Andrew C. Brown, Susan J. Baigent, Lorraine P. Smith, Jason P. Chattoo, Lawrence J. Petherbridge, Pippa Hawes, Martin J. Allday & Venugopal Nair
& Mihaela Zavolan (2006).
Baigent, S. J., Petherbridge, L. J., Smith, L. P.
, Chesters, P. M. and Nair
, V. (2006).
Davison, T. F. & Venugopal Nair
Marek's disease vaccines: Could they be driving the virulence?
Expert Reviews of Vaccines 4, 77-88.