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This profile was last updated on 11/12/15  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Stephen J. Chanock

Wrong Dr. Stephen J. Chanock?


Phone: (301) ***-****  
Local Address:  Gaithersburg , Maryland , United States
National Cancer Institute
6116 Executive Blvd. Room 3036A
Bethesda , Maryland 20892
United States

Company Description: The National Cancer Institute (NCI) is a component of the National Institutes of Health (NIH), one of eight agencies that compose the Public Health Service (PHS) in...   more

Employment History

  • Chief, Division of Cancer Epidemiology and Genetics
    National Cancer Institute
  • Cancer Geneticist
    National Cancer Institute
  • Chief of the Laboratory of Translational Genomics
    U.S. National Cancer Institute
  • Head of the Genomic Variation Section
    U.S. National Cancer Institute
  • Senior Investigator
    U.S. National Cancer Institute
  • Head of the Variation Section
  • Chief of Laboratory
    NCI Core Genotyping Facility
  • Member, Pediatric Oncology Branch
    NCI Core Genotyping Facility
  • Director of the NCI Core Genetics Facility and Co-Director

Board Memberships and Affiliations


  • M.D.
    Harvard Medical School
136 Total References
Web References
"Family history now matters more than ..., 12 Nov 2015 [cached]
"Family history now matters more than ever," says Stephen Chanock, a pediatric oncologist and head of the division of cancer epidemiology and genetics at the National Cancer Institute in Rockville, Maryland.
Dr Stephen Chanock, Chief, ..., 1 Mar 2015 [cached]
Dr Stephen Chanock, Chief, Division of Cancer Epidemiology and Genetics, NCI said: "We welcome this opportunity for Northern Ireland students to come to the National Institutes of Health.
There is, however, no direct proof ..., 29 Dec 2014 [cached]
There is, however, no direct proof that loss of Y sex chromosomes actually causes disease, cautions Stephen Chanock, a cancer geneticist at the National Cancer Institute in Bethesda, Maryland, who was not involved with the work.
Chanock agrees. "While the findings are intriguing," he says, "the associations between Y chromosome loss and shortened life span and disease risk do need to be confirmed in other large [long-term] studies."
"Because there is such a powerful ..., 2 April 2008 [cached]
"Because there is such a powerful environmental effect of smoking on lung cancer, we can't say for certain whether the association in that part of the genome is related directly to smoking or to the cancer process itself or an interaction of the two," said Dr. Stephen J. Chanock, chief of the Laboratory of Translational Genomics at the U.S. National Cancer Institute and co-author of an accompanying Nature editorial.
Chanock thinks the increased risk for lung cancer results from interaction of smoking and the variants' role in cancer.
"This region is contributing to smoking behavior, and it may also contribute to the process that leads cells astray to develop cancer, particularly in the lungs," Chanock said.
Anderson Cancer Center, Houston; Stephen J. Chanock, M.D., chief, Laboratory of Translational Genomics, U.S. National Cancer Institute, Bethesda, Md.; April 3, 2008, Nature; April 2, 2008, online, Nature Genetics
In the second report, Dr. Stephen ..., 12 Feb 2008 [cached]
In the second report, Dr. Stephen Chanock, head of the Genomic Variation Section at the U.S. National Cancer Institute, and his colleagues found genes associated with prostate cancer on chromosomes 7, 10 and 11, as well as nine other gene locations that are suggestive of an association with prostate cancer.
"We are finding the places in the genome that are associated with the risk for prostate cancer," Chanock said."The reason this is so important is that prostate cancer is a complex disease and is not due to one genetic defect or one environmental exposure," he said.
Similar findings are being reported with breast cancer, colon cancer and lung cancer, Chanock said."The same thing is happening in other diseases, such as diabetes, heart disease and stroke," he said."Most diseases are complex and associated with multiple genes."
Exactly how each of these genes contributes to the risk for prostate cancer isn't clear, Chanock said."Some of them may be responsive to environmental triggers, such as what you eat or what you inhale," he said.
SOURCES: Stephen Chanock, M.D., head, Genomic Variation Section, U.S. National Cancer Institute, Bethesda, Md.; Rosalind Eeles, M.D., Ph.D., Reader, Clinical Cancer Genetics, The Institute of Cancer Research, Sutton, U.K.; Durado Brooks, M.D., director, prostate and colorectal cancers, American Cancer Society, Atlanta; Feb. 10, 2008, Nature Genetics, online
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