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Wrong Stanley Jacob?

Stanley W. Jacob

Head of Transplantation Research

University of Oregon Medical School


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University of Oregon Medical School

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Background Information

Employment History

Professor of Surgery

Oregon Health & Science University




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Research Industries

Board Member

Phi Beta Kappa


Society for Cryobiology




American College of Surgeons


Oregon Medical Association


Society of University Surgeons


Life Extension Foundation

Medical Advisory Board


Graduate School at Walter Reed Army Medical Center



Ohio State University


Oregon Health Sciences Institute


Oregon Health Sciences Univ. Portland


Oregon Health Sciences University School of Medicine

bachelor's degree

Ohio State University

Web References(199 Total References)

All About Glucosamine and MSM [cached]

MSM (Methyl Sulfonyl Methane) was isolated by Robert Herschler and Dr. Stanley Jacob of the University of Oregon Medical School in the early 80's.
In his research, Dr. Jacob found that the sulfur in MSM, called Sulfonyl, is as safe and is as important as vitamin C in our diet. He observed that it is very different than the bad sulfurs like sulfite, often used to preserve certain foods. According to a recent book by Lawrence, Jacob, and Zucker, entitled The Miracle of MSM , MSM can be a natural remedy for osteoarthritis, rheumatoid arthritis, Fibromyalgia, tendonitis and bursitis, muscular soreness and athletic injuries, carpal tunnel syndrome, post-traumatic inflammation and pain, heartburn and hyperacidity, headaches and back pain, and allergies.

Kala Health MSM Pure | The History of MSM [cached]

In the late 1950s, Dr. Stanley Jacob, head of transplantation research at the University of Oregon Medical School, encountered a sulfur compound known as dimethylsulfoxide-DMSO-while trying to find a way to freeze organic tissue without damaging it.
While working with DMSO in the lab, he found that its medical use extended far beyond that of a cryoprotective agent. It showed analgesic and anti-inflammatory properties and promise as a skin-penetrating agent. Dr. Jacob hypothesized that DMSO would reduce pain when put over the location of an injury or localized bone or tissue illness. He began testing it in his laboratory, and eventually started using it to successfully treat patients in his clinic who suffered from unresolved arthritis, bursitis, tendinitis, and other conditions. In 1963, he reported it to the meeting of the American College of Surgeons, and before long, DMSO was on the front page of The New York Times, touted as "the most exciting thing in medicine. Under the cover of this state law, Dr. Stanley Jacob, who, along with fellow researchers at the University of Oregon Medical School had continued his research of DMSO's medical applications, was allowed to continue treating patients at his clinic, with continued success. In 1980, Mike Wallace of the CBS television show 60 Minutes decided to follow a California housewife named Sandy Sherrick as she sought DMSO treatment at Dr. Jacob's clinic for sever chronic whiplash and nerve damage that she had sustained in a car crash two years earlier. Wallace and his camera crew followed Sandy Sherrick as she received several days of intravenous treatment with DMSO and visited her house months afterwards to learn that she was still pain free without medication, and that she had returned to her normal activities for the first time since her accident. By this time, researchers had broken DMSO down into its components and had found that its major metabolite, DMSO2, was what provided its pain relieving and anti-inflammatory properties, along with other benefits. Dimethyl sulfone (DMSO2) is also known as methylsulfonylmethane, generally abbreviated to MSM. Dr. Jacob and his colleagues at the University of Oregon School of Medicine pursued their research of MSM and found that it was a highly promising molecule on its own, with the same benefits that had made DMSO popular, but without its unpleasant fishlike odor and taste, making it far more palatable for regular use.

Benefits of DMSO [cached]

Publisher's permission obtained to display Chapter-6 DMSO - The Persecuted Drug - Dr. Stanley Jacob [from the book Politics In Healing by Daniel Haley]
6. DSMO - The Persecuted Drug - Dr. Stanley Jacob This is also the story of a mild-mannered scientist (Dr Stanley Jacob) who challenged the law and defied the officials and their police in a soul-searing struggle to make the drug available wherever there is life. Dr. Stanley Jacob says within the first few hours is best and intravenously is better than oral, but oral works too. Once DMSO gets into the body either daubed on the skin, given I.V., or by mouth, it permeates the body and crosses the brain barricr, so even taken orally it can improve circulation. One man who had a stroke at 7:30 AM refused to go to the hospital until after his wife had spoken with Dr. Stanley Jacob, which didn't happen until 6:30 PM. Starting at 7 PM the day of the stroke, she gave him one ounce of 50% DMSO in a little orange juice every 15 minutes for two hours and then every half hour for two hours. The next day, her husband was better and soon returned to normal. Dr. Jacob first has given DMSO intravenously to people who were already paralyzed - paraplegics - and little by little they regained use of limbs. or check out this 5 minute video interview with Dr. Stanley W. Jacob Realizing there could be medical possibilities in DMSO, in 1961 Herschler got permission from his superiors to check with the University of Oregon Medical School in Portland, and was introduced to Stanley Jacob. Dr. Stanley Jacob, brilliant graduate (in surgery) of Harvard Medical School and professor of surgery on the faculty of the University of Oregon Medical School, had published 40 papers in prestigious medical journals before he heard of DMSO. Holder of numerous academic and professional honors, he was already a pioneer. Heart transplants were still the stuff of science fiction in 1961, but even then Jacob and his associates were getting puppy hearts to beat in mature dogs for several days, and he was looking for ways to preserve them. He found it in DMSO, which is now used worldwide for storage of organ transplants. After hearing about DMSO from Robert Herschler, Jacob painted some on his arm and within moments became aware of its oysterish taste in his mouth. As Pat McGrady put it, DMSO "was to change Stanley Jacob's life and what he learned about it was to change the lives of many others and had the capacity to change many more". Dr. Jacob and Herschler devised numerous experiments, one showing that mice which had sustained burns were more comfortable after being daubed with DMSO. "Apply DMSO on one side and see what happens", Jacob told him. Someone complained to Dr. Jacob of a splitting headache and gave him permission to apply some DMSO after hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for good after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman's sinusitis. A woman who had had a stroke found after DMSO was painted on her painful jaw that she could now write with her paralyzed hand and could walk better. Dr. Jacob found that it could also suppress inflammation. Dr Jacob asked her. "Because it doesn't hurt anymore", she replied. DMSO was very cheap, Herschler told Jacob. Impressed with what he was seeing but wanting someone skeptical to play devil's advocate, Dr. Jacob sought out Dr. Edward Rosenbaum, a physician in private practice in Portland. Rosenbaum did not pay much attention until a patient with severe bursitis started laughing, proclaiming his pain gone 15 minutes after his shoulder was painted with DMSO. Another colleague poopooed DMSO until after one of his bursititis patients had recovered via the chemical. He then declared that obviously the case must have been misdiagnosed - and asked if he should buy some stock in Crown Zellerbach (which produced DMSO). In 1963, Dr. Jacob and Robert Herschler submitted two papers on DMSO to medical journals. The patents were requested in the names of Herschler and Jacob and spelled out the major results seen from DMSO research, so the news was now public. The January and March 1964 issues of Northwest Medicine published articles by Jacob and Rosenbaum on bursitis and arthritis. This gave some legitimization to DMSO in scientific circles but stirred up animosity as well among those who resented hearing about DMSO first in the popular press. When Jacob presented his work to the University of Oregon Medical School faculty, there were a few jeers of "liar, charlatan, quack". It was hard for many to believe that something as versatile as DMSO could exist. Dr. Jacob sent a memo describing 20 of his cases to his immediate superior and friend, who replied with a note saying "This smacks of Andrew Ivy! A few months later, the same friend told Jacob that he had dreamed the previous night that the DMSO affair had been turned over to the National Academy of Sciences. Then Stan Jacob remembered his father's dream. A week before he died, his father said he had dreamed that Stan would find some wonderful chemical from wood, and people all over the world would be holding out their hands for it! The first Dr. Jacob and his colleagues knew of the animal tests was on November 10, 1965. Informed of the tests by Dr. Jacob and others showing that humans were not experiencing the same lens changes as the three animal species, the FDA at first seemed to have second thoughts. Had they overreacted? An FDA less eager to play "gotcha" might have handled the situation quite differently. Upon receiving the initial lens data, they might have immediately informed the drug companies and Dr. Jacob and asked them urgently to check if any humans were experiencing the same problems as the animals, which is what Jacob and his team did anyway, being responsible scientists. In 1965, the JAMA printed an article by Dr. Jacob on DMSO. Interestingly, his trouble has only been with the FDA, not the AMA. The JAMA has never turned down one of his articles, and he regularly writes its book reviews. On November 9, 1965, a top FDA official told Dr. Jacob that he had it on good authority that the Symposium would never be held, not explaining that he would announce the DMSO ban the next day. He was wrong. Dr. Chauncey Leake of the University of California Medical Center, who had agreed to chair the Symposium, told Dean Baird, Dr. Jacob's superior at the Medical School, that he'd been asked to drop plans for the symposium on the grounds that it would be embarrassing for both the drug companies and the FDA. Baird also told Jacob that Crown Zellerbach, unused to such controversy, had urged him to call off the symposium. I heard of Dr Jacob and went to visit him... McGrady noted that "scores of scientists confirmed the majority of claims Jacob had made... Distinguished scientists clustered around him and congratulated him for what some called a classical contribution to science and medicine". The very significant fact that DMSO would cross the blood brain barrier had been evident from Dr. Jacob's early research. Pat McGrady once asked Dr. Stanley Jacob who would gain the most from DMSO. Here is Dr. Jacob's answer. "Quadraplegia is the saddest thing that happens to people. It occurs most often to the young and healthy, to soldiers fighting our wars, to youngsters driving, to athletes in personal contact games. As a quadraplegic, you lie in bed, a total vegetable. Your mind functions but you cannot pass urine or have a bowel movement without help... So many of them eventually say to me 'Dr. Jacob, I couldn't even commit suicide'. Jacob told McGrady about one such patient, a case where he was called in almost immediately following an accident. Grey Keinsley of Littleton, Colorado, is the one-time quadraplegic mentioned earlier by Dr. Jacob, who went on to college and to ajob in a bank. His mother told McGrady that Dr. Jacob not only did not charge for his services, but paid bills for extensive medical examinations which were done in Colorado. Dr. Jacob has seen two quadraplegic patients recover completely when DMSO was started within one hour after the accident. In 1971, Squibb Pharmaceutica

MSM Information and Products [cached]

MSM (Methyl Sulfonyl Methane) was isolated by Robert Herschler and Dr. Stanley Jacob of the University of Oregon Medical School in the early 80's.

Jini's Healing Guide: Natural Treatments for Intestinal Strictures (eBook) - by Jini Patel Thompson - LTYG Shoppe [cached]

DMSO (dimethyl sulfoxide) - Dr. Stanley Jacob of the University of Oregon Medical School discovered that DMSO relieved burn pains and prevented scar tissue formation.
He published his results in 1963 - and from then on DMSO usage and experimentation spread like wildfire.

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