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This profile was last updated on 12/18/14  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Staci A. Gruber

Wrong Dr. Staci A. Gruber?

Director , Cognitive and Clinical...

Local Address: Belmont, Massachusetts, United States
Harvard Medical School
1545 Massachusetts Avenue
Cambridge , Massachusetts 02138
United States

Company Description: Harvard Medical School has more than 7,500 full-time faculty working in 11 academic departments located at the School's Boston campus or in one of 47 hospital-based...   more
Background

Employment History

Board Memberships and Affiliations

  • Director
    Cognitive and Clinical Neuroimaging Core

Education

  • Ph.D.
88 Total References
Web References
The conversation was moderated by ...
www.thecrimson.com, 8 Oct 2014 [cached]
The conversation was moderated by Dr. Staci Gruber, an Associate Professor of Psychiatry at Harvard Medical School.
...
The John F. Kennedy Jr. Forum event, moderated by Harvard Medical School associate professor Staci A. Gruber, comes just two days after the Harvard-affiliated McLean Hospital announced a "landmark new program" examining medical marijuana.
...
Gruber then shared a clip from Gupta's documentary "Weed," highlighting the story of Charlotte Figi, a five-year-old suffering from severe epilepsy.
Cannabis Activist Network
cannabisactivistnetwork.com, 9 Oct 2014 [cached]
MIND head researcher Staci A. Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and assistant professor of psychology at Harvard Medical School, hopes that the new initiative, the first of its kind, will begin to answer questions about whether medical marijuana affects cognitive function, positively or negativelyâ€"and whyâ€"by gathering empirical data about change over time within patients.
...
If the program were to grow, Gruber says, the next phase would use the collected data to design and conduct clinical trials, administering the drug to individuals.
...
As Gruber puts it, “Policy has outpaced science.†For example, though patients have a variety of methods for taking medical marijuana, including as vapor, oil, tincture, or smoke, these substances bear little resemblance to the manufactured, standardized cannabinoidsâ€"the chemical compound patients need from the marijuanaâ€"studied in many trials; most of these synthetic versions have yet to reach end-users. (Gruber hopes to gather and analyze samples of what her subjects are using.) A June 2014 literature review in the New England Journal of Medicine, surveying the gaps in current knowledge, singled out what it called “the need to improve our understanding of how to harness the potential medical benefits of the marijuana plant without exposing people who are sick to its intrinsic risks.â€
In a press release, Gruber stated that marijuana, which has “shown promise in alleviating a range of symptoms, could potentially improve cognitive performance†of patients suffering from severe medical disorders that disrupt their cognitive function and mood. “Equally critical,†she added, is that “Data showing a loss or impairment of cognitive function following the use of medical marijuana could inform alternative courses of treatment and prevent unjustified exposure to harm, especially in vulnerable populations.â€
Gruber’s previous research into the subject has focused on the impact of heavy recreational marijuana use on the developing brainâ€"a question increasing in urgency as use has begun to climb among high-school students after more than a decade of decline (even as cigarette smoking and alcohol use continue to drop). Her studies have found that the drug alters white-matter connections in the brain and reduces inhibitions, resulting in more impulsive behavior. On MRI scans taken while participants completed cognitive tests, early-onset marijuana smokers activated a different part of the brain region controlling inhibition, attention, and error processing than did late smokers. (Gruber has appeared on ABC’s Nightline and on the Dr. Sanjay Gupta’s CNN documentary Weed to speak about her findings, and will moderate a conversation with Gupta on medical marijuana at Harvard’s Institute of Politics tonight, October 8, at 6 P.M.)
Patricia Cornwell, who funded the program, is also a supporter of the Harvard Art Museum: she endowed the position of Cornwell Conservation Scientist at the Straus Center, and has donated collections of works by James McNeill Whistler, Augustus Edwin John, and Walter Sickert, in addition to advanced technological equipment. Her relationship with McLean coincides with her relationship with Gruber: they met when Cornwell visited McLean, on the recommendation of her contact at the Fogg Museum, to learn about brain imaging for a book project. “She asked incredibly good questions,†Gruber recalls.
...
MIND head researcher Staci A. Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and assistant professor of psychology at Harvard Medical School, hopes that the new initiative, the first of its kind, will begin to answer questions about whether medical marijuana affects cognitive function, positively or negativelyâ€"and whyâ€"by gathering empirical data about change over time within patients.
...
If the program were to grow, Gruber says, the next phase would use the collected data to design and conduct clinical trials, administering the drug to individuals.
...
As Gruber puts it, “Policy has outpaced science.†For example, though patients have a variety of methods for taking medical marijuana, including as vapor, oil, tincture, or smoke, these substances bear little resemblance to the manufactured, standardized cannabinoidsâ€"the chemical compound patients need from the marijuanaâ€"studied in many trials; most of these synthetic versions have yet to reach end-users. (Gruber hopes to gather and analyze samples of what her subjects are using.) A June 2014 literature review in the New England Journal of Medicine, surveying the gaps in current knowledge, singled out what it called “the need to improve our understanding of how to harness the potential medical benefits of the marijuana plant without exposing people who are sick to its intrinsic risks.â€
In a press release, Gruber stated that marijuana, which has “shown promise in alleviating a range of symptoms, could potentially improve cognitive performance†of patients suffering from severe medical disorders that disrupt their cognitive function and mood. “Equally critical,†she added, is that “Data showing a loss or impairment of cognitive function following the use of medical marijuana could inform alternative courses of treatment and prevent unjustified exposure to harm, especially in vulnerable populations.â€
Gruber’s previous research into the subject has focused on the impact of heavy recreational marijuana use on the developing brainâ€"a question increasing in urgency as use has begun to climb among high-school students after more than a decade of decline (even as cigarette smoking and alcohol use continue to drop). Her studies have found that the drug alters white-matter connections in the brain and reduces inhibitions, resulting in more impulsive behavior. On MRI scans taken while participants completed cognitive tests, early-onset marijuana smokers activated a different part of the brain region controlling inhibition, attention, and error processing than did late smokers. (Gruber has appeared on ABC’s Nightline and on the Dr. Sanjay Gupta’s CNN documentary Weed to speak about her findings, and will moderate a conversation with Gupta on medical marijuana at Harvard’s Institute of Politics tonight, October 8, at 6 P.M.)
Patricia Cornwell, who funded the program, is also a supporter of the Harvard Art Museum: she endowed the position of Cornwell Conservation Scientist at the Straus Center, and has donated collections of works by James McNeill Whistler, Augustus Edwin John, and Walter Sickert, in addition to advanced technological equipment. Her relationship with McLean coincides with her relationship with Gruber: they met when Cornwell visited McLean, on the recommendation of her contact at the Fogg Museum, to learn about brain imaging for a book project. “She asked incredibly good questions,†Gruber recalls.
A. Edin Evins, MD, Director of ...
mghmcleanpsychiatry.partners.org, 14 Oct 2014 [cached]
A. Edin Evins, MD, Director of Center for Addiction Medicine at MGH and Staci Gruber, PhD, Director of the Cognitive and Clinical Neuroimaging Core at McLean Hospital, were quoted in a recent New York Times article concerning recent changes in the legality of marijuana.
...
Dr. Gruber addressed the dangers of marijuana use in teens and young adults, whose brains are still developing. "The frontal cortex is the last part of the brain to come online, and the most important," said Dr. Gruber.
"Anything that underscores that there may ...
www.studentnewsdaily.com [cached]
"Anything that underscores that there may be structural changes in the brain [from marijuana use] is important," said Dr. Staci Gruber, an associate psychiatry professor at Harvard Medical School and a director of brain imaging at McLean Hospital.
Pot Said to Damage Young Users’ Brains
www.friendsofrecoveryvt.org, 16 Nov 2010 [cached]
Research on how marijuana changes a developing brain is important as it's the most frequently used illegal drug in the United States, said study author Staci Gruber, the director of the neuroimaging center at McLean Hospital in Belmont, Mass. Almost 16 percent of eighth graders have tried marijuana, and that number rises to 42 percent by 12th grade, a 2009 study from the National Institute on Drug Abuse found.
Chronic, early users of marijuana "make repetitive incorrect responses despite the fact I'm telling them they're wrong," said Gruber, who is also an assistant professor of psychology at Harvard University. "That's called 'cognitive inflexibility' and you see it in babies."
The research, presented yesterday at the Society for Neuroscience's meeting in San Diego, also found that the group that started earlier smoked more pot more often than those who started later. People who began smoking before age 16 had 25.1 smokes a week, compared with 12.1 in those who began later, the study showed. The early-onset group smoked almost three times as many grams a week, Gruber said.
...
The research didn't examine those people who had started smoking early and stopped, although those people begin to look more like non-smokers in other studies, Gruber said.
"The developing brain is vulnerable," Gruber said.
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