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This profile was last updated on 2/7/16  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Staci A. Gruber

Wrong Dr. Staci A. Gruber?

Director, Cognitive and Clinical ...

Phone: (617) ***-****  
Email: g***@***.edu
Local Address:  Belmont , Massachusetts , United States
Harvard Medical School
180 Longwood Avenue
Boston , Massachusetts 02115
United States

Company Description: Harvard Medical School has more than 7,500 full-time faculty working in 11 academic departments located at the School's Boston campus or in one of 47 hospital-based...   more
Background

Employment History

Board Memberships and Affiliations

  • Director
    Cognitive and Clinical Neuroimaging Core

Education

  • Ph.D.
107 Total References
Web References
Dr. Staci ...
aspenbrainlab.com, 7 Feb 2016 [cached]
Dr. Staci Gruber
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Dr. Staci Gruber
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Dr. Staci Gruber, Director, Cognitive and Clinical Neuroimaging Core, McLean Hospital Associate Professor of Psychiatry, Harvard Medical School
...
Dr. Staci Gruber is the Director of the Cognitive and Clinical Neuroimaging Core at McLean Hospital's Brain Imaging Center and an Associate Professor of Psychiatry at Harvard Medical School. Dr. Gruber's clinical and research focus is the application of neurocognitive models and multimodal brain imaging to better characterize neurobiological risk factors for substance abuse and psychopathology, particularly disruptions of the frontal network. In recent work, her lab has examined the etiologic bases of neural models of dysfunction in patients with bipolar disorder as well as marijuana-abusing adults, the results of which have been published in numerous peer reviewed journals and been the basis of national and international symposia and press conferences. Dr. Gruber has also been involved in the application of behavioral science to help shape policies regarding juvenile advocacy and defense; her lab's work in adolescent development was part of the Amicus brief leading to the Supreme Court's landmark decision in Roper v. Simmons, which states that it is unconstitutional to execute minors. Her ongoing initiative to educate policymakers, judges, attorneys and the general public in the differences between adults and adolescents has already had both local and national impact on policy formation.
Cannabis Activist Network
cannabisactivistnetwork.com, 9 Oct 2014 [cached]
MIND head researcher Staci A. Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and assistant professor of psychology at Harvard Medical School, hopes that the new initiative, the first of its kind, will begin to answer questions about whether medical marijuana affects cognitive function, positively or negativelyâ€"and whyâ€"by gathering empirical data about change over time within patients.
...
If the program were to grow, Gruber says, the next phase would use the collected data to design and conduct clinical trials, administering the drug to individuals.
...
As Gruber puts it, “Policy has outpaced science.â€� For example, though patients have a variety of methods for taking medical marijuana, including as vapor, oil, tincture, or smoke, these substances bear little resemblance to the manufactured, standardized cannabinoidsâ€"the chemical compound patients need from the marijuanaâ€"studied in many trials; most of these synthetic versions have yet to reach end-users. (Gruber hopes to gather and analyze samples of what her subjects are using.) A June 2014 literature review in the New England Journal of Medicine, surveying the gaps in current knowledge, singled out what it called “the need to improve our understanding of how to harness the potential medical benefits of the marijuana plant without exposing people who are sick to its intrinsic risks.â€�
In a press release, Gruber stated that marijuana, which has “shown promise in alleviating a range of symptoms, could potentially improve cognitive performance� of patients suffering from severe medical disorders that disrupt their cognitive function and mood. “Equally critical,� she added, is that “Data showing a loss or impairment of cognitive function following the use of medical marijuana could inform alternative courses of treatment and prevent unjustified exposure to harm, especially in vulnerable populations.�
Gruber’s previous research into the subject has focused on the impact of heavy recreational marijuana use on the developing brainâ€"a question increasing in urgency as use has begun to climb among high-school students after more than a decade of decline (even as cigarette smoking and alcohol use continue to drop). Her studies have found that the drug alters white-matter connections in the brain and reduces inhibitions, resulting in more impulsive behavior. On MRI scans taken while participants completed cognitive tests, early-onset marijuana smokers activated a different part of the brain region controlling inhibition, attention, and error processing than did late smokers. (Gruber has appeared on ABC’s Nightline and on the Dr. Sanjay Gupta’s CNN documentary Weed to speak about her findings, and will moderate a conversation with Gupta on medical marijuana at Harvard’s Institute of Politics tonight, October 8, at 6 P.M.)
Patricia Cornwell, who funded the program, is also a supporter of the Harvard Art Museum: she endowed the position of Cornwell Conservation Scientist at the Straus Center, and has donated collections of works by James McNeill Whistler, Augustus Edwin John, and Walter Sickert, in addition to advanced technological equipment. Her relationship with McLean coincides with her relationship with Gruber: they met when Cornwell visited McLean, on the recommendation of her contact at the Fogg Museum, to learn about brain imaging for a book project. “She asked incredibly good questions,� Gruber recalls.
...
MIND head researcher Staci A. Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and assistant professor of psychology at Harvard Medical School, hopes that the new initiative, the first of its kind, will begin to answer questions about whether medical marijuana affects cognitive function, positively or negativelyâ€"and whyâ€"by gathering empirical data about change over time within patients.
...
If the program were to grow, Gruber says, the next phase would use the collected data to design and conduct clinical trials, administering the drug to individuals.
...
As Gruber puts it, “Policy has outpaced science.â€� For example, though patients have a variety of methods for taking medical marijuana, including as vapor, oil, tincture, or smoke, these substances bear little resemblance to the manufactured, standardized cannabinoidsâ€"the chemical compound patients need from the marijuanaâ€"studied in many trials; most of these synthetic versions have yet to reach end-users. (Gruber hopes to gather and analyze samples of what her subjects are using.) A June 2014 literature review in the New England Journal of Medicine, surveying the gaps in current knowledge, singled out what it called “the need to improve our understanding of how to harness the potential medical benefits of the marijuana plant without exposing people who are sick to its intrinsic risks.â€�
In a press release, Gruber stated that marijuana, which has “shown promise in alleviating a range of symptoms, could potentially improve cognitive performance� of patients suffering from severe medical disorders that disrupt their cognitive function and mood. “Equally critical,� she added, is that “Data showing a loss or impairment of cognitive function following the use of medical marijuana could inform alternative courses of treatment and prevent unjustified exposure to harm, especially in vulnerable populations.�
Gruber’s previous research into the subject has focused on the impact of heavy recreational marijuana use on the developing brainâ€"a question increasing in urgency as use has begun to climb among high-school students after more than a decade of decline (even as cigarette smoking and alcohol use continue to drop). Her studies have found that the drug alters white-matter connections in the brain and reduces inhibitions, resulting in more impulsive behavior. On MRI scans taken while participants completed cognitive tests, early-onset marijuana smokers activated a different part of the brain region controlling inhibition, attention, and error processing than did late smokers. (Gruber has appeared on ABC’s Nightline and on the Dr. Sanjay Gupta’s CNN documentary Weed to speak about her findings, and will moderate a conversation with Gupta on medical marijuana at Harvard’s Institute of Politics tonight, October 8, at 6 P.M.)
Patricia Cornwell, who funded the program, is also a supporter of the Harvard Art Museum: she endowed the position of Cornwell Conservation Scientist at the Straus Center, and has donated collections of works by James McNeill Whistler, Augustus Edwin John, and Walter Sickert, in addition to advanced technological equipment. Her relationship with McLean coincides with her relationship with Gruber: they met when Cornwell visited McLean, on the recommendation of her contact at the Fogg Museum, to learn about brain imaging for a book project. “She asked incredibly good questions,� Gruber recalls.
Pot Said to Damage Young Users’ Brains
www.friendsofrecoveryvt.org, 16 Nov 2010 [cached]
Research on how marijuana changes a developing brain is important as it's the most frequently used illegal drug in the United States, said study author Staci Gruber, the director of the neuroimaging center at McLean Hospital in Belmont, Mass. Almost 16 percent of eighth graders have tried marijuana, and that number rises to 42 percent by 12th grade, a 2009 study from the National Institute on Drug Abuse found.
Chronic, early users of marijuana "make repetitive incorrect responses despite the fact I'm telling them they're wrong," said Gruber, who is also an assistant professor of psychology at Harvard University. "That's called 'cognitive inflexibility' and you see it in babies."
The research, presented yesterday at the Society for Neuroscience's meeting in San Diego, also found that the group that started earlier smoked more pot more often than those who started later. People who began smoking before age 16 had 25.1 smokes a week, compared with 12.1 in those who began later, the study showed. The early-onset group smoked almost three times as many grams a week, Gruber said.
...
The research didn't examine those people who had started smoking early and stopped, although those people begin to look more like non-smokers in other studies, Gruber said.
"The developing brain is vulnerable," Gruber said.
"Anything that underscores that there may ...
www.studentnewsdaily.com [cached]
"Anything that underscores that there may be structural changes in the brain [from marijuana use] is important," said Dr. Staci Gruber, an associate psychiatry professor at Harvard Medical School and a director of brain imaging at McLean Hospital.
Young people "don't think it's risky," ...
www.klewtv.com, 23 Dec 2011 [cached]
Young people "don't think it's risky," said Staci Gruber, a researcher at the Harvard-affiliated MacLean Hospital in Belmont, Mass. Gruber, who didn't participate in the new work, said the idea that marijuana harms the adolescent brain is "something we believe is very likely," and the new finding of IQ declines warrants further investigation.
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