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Wrong Staci Gruber?

Staci A. Gruber

Associate Professor of Psychiatry

Harvard Companies, Inc.

HQ Phone:  (617) 432-1000

Direct Phone: (617) ***-****direct phone

Email: g***@***.edu


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I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Community Edition at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

Harvard Companies, Inc.

25 Shattuck Street, Room 306A

Boston, Massachusetts,02115

United States

Company Description

Harvard Medical School has more than 7,500 full-time faculty working in 11 academic departments located at the School's Boston campus or in one of 47 hospital-based clinical departments at 17 Harvard-affiliated teaching hospitals and research institutes. Those...more

Background Information

Employment History

Director of the Cognitive and Clinical Neuroimaging Core

McLean Hospital


No Kidding , Me 2

Scientific Advisor


PhD Listen

Harvard Medical School

graduate degrees

psychology and experimental cognitive neuroscience

Tufts University

Web References(162 Total References)

all | Staff Biographies | McLean Hospital [cached]

Staci Gruber, PhD
Staci Gruber, PhD

Cannabis Health Benefits Report Shows Need For More Research [cached]

"Cannabis has been around for thousands of years; it's not like we just made it up in a lab," Staci Gruber, associate professor of Psychiatry at Harvard Medical School and director of the Marijuana Investigations for Neuroscientific Discovery program at McLean Hospital told Business Insider in a recent interview.

Gift Funds Neuroscience Research into Medical Marijuana | LDRFA [cached]

MIND head researcher Staci A. Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and associate professor of psychiatry at Harvard Medical School, hopes that the new initiative, the first of its kind, will begin to answer questions about whether medical marijuana affects cognitive function, positively or negatively-and why-by gathering empirical data about change over time within patients.
The initial phase of the program is expected to run for approximately two years. Researchers will collect data from subjects who, suffering from conditions including pain, anxiety, and post-traumatic stress disorder, have been certified to take medical marijuana but have no substantial history of recreational use, and have not yet begun this course of treatment. Participants will take a number of cognitive tests, on paper and on the computer, and will undergo brain scans. The studies will also gather clinical information on the patients' perceptions about how they feel, and about their quality of life. After a baseline is established, the subjects will maintain weekly contact with the researchers, checking in physically with the hospital at the three-month, six-month, and one-year mark for more extensive tests, including some using multi-modal imaging equipment. If the program were to grow, Gruber says, the next phase would use the collected data to design and conduct clinical trials, administering the drug to individuals. As Gruber puts it, "Policy has outpaced science. For example, though patients have a variety of methods for taking medical marijuana, including as vapor, oil, tincture, or smoke, these substances bear little resemblance to the manufactured, standardized cannabinoids-the chemical compound patients need from the marijuana-studied in many trials; most of these synthetic versions have yet to reach end-users. (Gruber hopes to gather and analyze samples of what her subjects are using.) A June 2014 literature review in the New England Journal of Medicine, surveying the gaps in current knowledge, singled out what it called "the need to improve our understanding of how to harness the potential medical benefits of the marijuana plant without exposing people who are sick to its intrinsic risks." In a press release, Gruber stated that marijuana, which has "shown promise in alleviating a range of symptoms, could potentially improve cognitive performance" of patients suffering from severe medical disorders that disrupt their cognitive function and mood. "Equally critical," she added, is that "Data showing a loss or impairment of cognitive function following the use of medical marijuana could inform alternative courses of treatment and prevent unjustified exposure to harm, especially in vulnerable populations." Gruber's previous research into the subject has focused on the impact of heavy recreational marijuana use on the developing brain-a question increasing in urgency as use has begun to climb among high-school students after more than a decade of decline (even as cigarette smoking and alcohol use continue to drop). Her studies have found that the drug alters white-matter connections in the brain and reduces inhibitions, resulting in more impulsive behavior. On MRI scans taken while participants completed cognitive tests, early-onset marijuana smokers activated a different part of the brain region controlling inhibition, attention, and error processing than did late smokers. (Gruber has appeared on ABC's Nightline and on the Dr. Sanjay Gupta's CNN documentary Weed to speak about her findings, and will moderate a conversation with Gupta on medical marijuana at Harvard's Institute of Politics tonight, October 8, at 6 P.M.) Patricia Cornwell, who funded the program, is also a supporter of the Harvard Art Museum: she endowed the position of Cornwell Conservation Scientist at the Straus Center, and has donated collections of works by James McNeill Whistler, Augustus Edwin John, and Walter Sickert, in addition to advanced technological equipment. Her relationship with McLean coincides with her relationship with Gruber: they met when Cornwell visited McLean, on the recommendation of her contact at the Fogg Museum, to learn about brain imaging for a book project.

Marijuana Mental Effects | Clinical Study | Effect on Mind [cached]

In a paper that will be presented on Monday, Nov. 15 at the annual meeting of the Society for Neuroscience in San Diego, Staci A. Gruber, PhD, reported that subjects who started using marijuana before age 16 made twice as many mistakes on tests of executive function, which includes planning, flexibility, abstract thinking and inhibiting inappropriate responses as those who began smoking after age 16.
"They performed significantly worse," said Gruber, director of the Cognitive and Clinical Neuroimaging Core at McLean and assistant professor of Psychiatry at Harvard Medical School. Gruber said the findings are particularly critical today when legalization of marijuana is being considered in a number of states. "We have to be clear about getting the message out that marijuana isn't really a benign substance," she said. "Our results provide further evidence that marijuana use has a direct effect on executive function and that both age of onset and magnitude of marijuana use can significantly influence cognitive processing," said Gruber. "Given the prevalence of marijuana use in the United States, these findings underscore the importance of establishing effective strategies to decrease marijuana use, especially in younger populations," she said.

TOP Cannabis Documentaries [cached]

Dr. Sanjay Gupta, Chief Medical Correspondent at CNN, joined Dr. Staci Gruber, Associate Professor of Psychiatry at Harvard Medical School, for a discussion on medical marijuana.

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