Sheng-Xing Ma, MD, PhD, associate professor at UCLA, David Geffen School of Medicine, summarizes "acupuncture point, 'St 36', decreases heart blood pressure and heart rate."5 He notes "L-arginine derived NO [nitric oxide] in the gracile nucleus and mNTS [medial portion nucleus tractus solitarius] mediates CV reflex responses to electro-stimulation at acupuncture point, 'St 36'."5 He describes the dorsal-medulla-thalamic tract to be the important pathway for acupuncture signals.
Up-regulation of nNOS-NO [neuronal NO synthase] in the pathways mediates the non-opioid effects of electro-stimulation at acupuncture point, 'St 36'.6
research shows NO is generated from the skin surface with a high level existence at acupuncture points and possibly at meridians lines.
Thus, Dr. Ma
concludes NO modifies skin electricity which creates low resistance characteristics for acupuncture points, raises the conductance, increases signal flow and the therapeutic effect.