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2012-04-25T00:00:00.000Z

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Wrong Sanjay Phogat?

Dr. Sanjay Phogat K.

Director, Vaccine Project Leader

Sanofi Pasteur Limited

HQ Phone: (570) 839-7187

Email: s***@***.com

Sanofi Pasteur Limited

BLDG 38, 1 DISCOVERY DR

SWIFTWATER, Pennsylvania 18370

United States

Company Description

Sanofi, a global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients' needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal heal... more

Find other employees at this company (6,570)

Background Information

Employment History

Principal Investigator

International AIDS Vaccine Initiative

Principal Scientist Immunogen Design

International AIDS Vaccine Initiative

Secretary and Vice President

The Indian Association of Frederick Inc

Affiliations

Founding Member
National Institutes of Health

Board Member
Global Alliance of Indian Biomedical Professional

Secretary
Fellows Committee

Education

B.S.
Microbiology
University of Delhi

Ph.D.
Genetics
University of Delhi

M.S.
Biotechnology
Madurai Kamaraj University

Web References (20 Total References)


IMAPAC - Speaker

www.imapac.com [cached]

Dr Sanjay K. Phogat, Director, New Vaccine Project Leader, Sanofi Pasteur, USA Sanjay Phogat, currently holds the position of Director, New Vaccine Project Leader for Sanofi Pasteur and is based in Swiftwater, Pennsylvania. Prior to joining Sanofi Pasteur in 2011, Sanjay held positions such as Associate Director, Principal Scientist, Project Manager, Neutralizing Antibody Consortium Principal Investigator at International AIDS Vaccine Initiative (IAVI) in Brooklyn, New York. At IAVI, he led the efforts and was a key member of the discovery team that isolated and characterized novel, potent broadly neutralizing antibodies (bNAbs), which are considered a "milestone achievement" in the field of HIV vaccine research. He has a wealth of experience in HIV-1 neutralizing antibodies and envelope-based vaccine candidates. Sanjay also worked as a Research Assistant Professor at the State University of New York, Downstate Medical Center, Brooklyn, New York, Research Fellow at the Vaccine Research Center, NIAID, NIH and Post-doctoral Fellow at NCI-Frederick and USUHS, in Bethesda, Maryland. He holds a Ph.D. in Genetics from the University of Delhi, Delhi, India, an M.S. in Biotechnology from Madurai Kamaraj University in Chennai, India, and a B.S. in Microbiology from University of Delhi in India. Dr. Phogat has numerous publications in peer reviewed journals and participates as associate editor/reviewer for certain peer-reviewed journals.


IAVI Team | IAVI - International AIDS Vaccine Initiative

www.iavi.org [cached]

Sanjay K Phogat

Principal Scientist Immunogen Design and Project Manager Medicin
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Dr. Sanjay K. Phogat comes to IAVI from the Vaccine Research Center (VRC), National Institute of Health, DHHS. He has a wealth of experience in HIV-1 neutralizing antibodies. At NCI-Frederick, in collaboration with Drs. Dennis Burton and Dimiter Dimitrov, he and his colleagues discovered the Fab X5 which has been licensed and is now being developed as a therapeutic against HIV. Dr. Phogat's work at NCI-Frederick and at the VRC has lead to insight into various HIV-1 vaccine candidates, use of gp140s, tethered envelope glycoprotein, Env-CD4-CCR5 complexes, Hepatitis B surface antigen as a particulate vaccine platform for the membrane proximal region of gp41 and generation of unconventional second-generation vaccine candidates using host molecules. Dr. Phogat developed an ingenious method for studying G-protein coupled receptors in ELISA format, this strategy would help study many orphan receptors and identify HIV inhibitors. The use of rational vaccine design is a new paradigm that Dr. Phogat is pursuing very intently. Dr. Phogat received numerous awards during his career: to name a few, the prestigious gold medal given by the late Excellency President of India K. R. Narayanan, Technology transfer awards by the National Cancer Institute and the Fellows award for research excellence by NIH.
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Dr. Phogat is also a founding member of NIH visiting Fellows committee, a board member of Global Alliance of Indian Biomedical Professional, former secretary of Fellows Committee (FELCOM) and former Secretary and Vice-President of Indian Association of Frederick.


The Stem of Vesicular Stomatitis Virus ...

www.iavireport.org [cached]

The Stem of Vesicular Stomatitis Virus G can be replaced with the HIV-1 Env Membrane-Proximal External Region (MPER) without loss of G function or MPER antigenic properties Lorenz, I. C. (IAVI), H. T. Nguyen (IAVI) , M. Kemelman (IAVI) , R. W. Lindsay (IAVI) , M. Yuan (IAVI) , K. J. Wright (IAVI) , H. Arendt (IAVI) , J. W. Back, J. Destefano, S. (IAVI) Hoffenberg (IAVI) , G. Morrow (IAVI) , C. K. Jurgens (IAVI) , S. K. Phogat (IAVI) , T. J. Zamb (IAVI) and C. Parks (IAVI) AIDS Research and Human Retroviruses [read more...]


Sanjay Phogat (International ...

www.nyas.org [cached]

Sanjay Phogat (International AIDS Vaccine Initiative)

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Sanjay Phogat, International AIDS Vaccine Initiative
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To accomplish this with vaccines, said Sanjay Phogat of the International AIDS Vaccine Initiative (IAVI), "we need neutralizing antibodies that can really cover the entire variability. In the past few years researchers have made significant progress in screening infected people for "broad neutralizing antibodies. Identifying the conserved molecular regions, or epitopes, that these antibodies target, may let researchers design antigens that elicit these antibodies in unexposed people.
"We need neutralizing antibodies that can cover the entire variability of the HIV virus."
The key to the recent progress is screening for antibodies that neutralize viral activity, rather than simply binding to viruses, Phogat said. Recent advanced techniques, requiring just a few antibody-producing B cells from a patient's serum, enable screening of many viral variants simultaneously for neutralizing ability.
Phogat reviewed the improved antibody screening approaches used by several labs. The NIH Vaccine Research Center (VRC) looks for binding to a target that was designed to expose specific regions of the envelope glycoproteins. "They got a very broad neutralizing antibody, VRC-01, that is dedicated to the CD4 binding site on the virus," Phogat noted. In parallel, the Collaboration for AIDS Vaccine Discovery (CAVD) used binding followed by a neutralization screen to find broad neutralizing antibodies, notably one designated HJ16.
Phogat and his colleagues at IAVI and The Scripps Research Institute took pains to collect, and to characterize well, samples from around the world. One patient from their "Protocol G" yielded two excellent antibodies, denoted PG9 and PG16. "These are very potent and broad neutralizing antibodies. Phogat said.
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Sanjay Phogat (International AIDS Vaccine Initiative)
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Sanjay Phogat, IAVI
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Sanjay Phogat
Corti D, Langedijk JP, Hinz A, et al. 2010. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.PLoS One 5: e8805. Full Text
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Sanjay Phogat, PhD
International AIDS Vaccine Initiative e-mail | web site | publications
Sanjay K. Phogat is a principal scientist at the International AIDS Vaccine Initiative's AIDS Vaccine Design and Development laboratory located in Brooklyn, N.Y. He is also a principal investigator of the IAVI Neutralizing Antibody Consortium (NAC). His research focus is on HIV-1 broad neutralizing antibodies, including HIV-1 envelope glycoprotein-based immunogen design and their presentation on a particulate platform. In addition, Phogat is involved with the IAVI medicinal chemistry research program in India, a partnership with the Indian government's Department of Biotechnology and supports several projects that are within the organization's Innovation Fund portfolio.
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In fact, Phogat was integrally involved in the recent discovery of two new potent and broadly neutralizing antibodies against HIV, PG9 and PG16, a finding that grew out of the Innovation Fund and IAVI's network of research centers in the developing world.
Prior to joining IAVI Phogat worked at the Vaccine research center. Phogat received numerous awards during his career: to name a few, the prestigious gold medal given by the late Excellency President of India K. R. Narayanan, Technology transfer awards by the National Cancer Institute and the Fellows award for research excellence by NIH.
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Phogat is also a founding member of NIH visiting Fellows committee, a board member of Global Alliance of Indian Biomedical Professional and former secretary of Fellows Committee (FELCOM).


HIV/AIDS | The New York Academy of Sciences

www.nyas.org [cached]

Sanjay Phogat, International AIDS Vaccine Initiative

11:15 AM
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Sanjay Phogat
International AIDS Vaccine Initiative
Dr. Sanjay K. Phogat is a Principal Scientist at the International AIDS Vaccine Initiative's AIDS Vaccine Design and Development laboratory located in Brooklyn, N.Y. He is also a Principal Investigator of the IAVI Neutralizing Antibody Consortium (NAC). His research focus is on HIV-1 broad neutralizing antibodies, including HIV-1 envelope glycoprotein-based immunogen design and their presentation on a particulate platform. In addition, Dr. Phogat is involved with the IAVI medicinal chemistry research program in India, a partnership with the Indian government's Department of Biotechnology and supports several projects that are within the organization's Innovation Fund portfolio.
...
In fact, Dr. Phogat was integrally involved in the recent discovery of two new potent and broadly neutralizing antibodies against HIV, PG9 and PG16, a finding that grew out of the Innovation Fund and IAVI's network of research centers in the developing world. Prior to joining IAVI Dr. Phogat worked at the Vaccine research center. Dr. Phogat received numerous awards during his career: to name a few, the prestigious gold medal given by the late Excellency President of India K. R. Narayanan, Technology transfer awards by the National Cancer Institute and the Fellows award for research excellence by NIH.
...
Dr. Phogat is also a founding member of NIH visiting Fellows committee, a board member of Global Alliance of Indian Biomedical Professional and former secretary of Fellows Committee (FELCOM).
...
Sanjay Phogat, IAVI

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