The Dalhousie University, Department of Bioethics homepage, this site provides an introduction to bioethics, covering its history and current hot topics. It briefly describes and links to a few select websites and has a bibliography covering academic book
Dermatologist Dr. Richard G. B. Langley, MD, FRCPC, FACP, will be offering the visiting clinic twice a month and may increase to weekly clinics over time.r. Langley is also a professor and director of research in the Division of Dermatology with Dalhousie University's Department of Medicine, and president of the Canadian Dermatology Association.
Health Canada rubber stamps psoriasis treatment discovered through Dalâ€‘led research - Faculty of Medicine - Dalhousie University
The injection, the first treatment of its kind, was discovered and tested by an international team of researchers led by Dalhousie Medical School'sDr. Richard Langley.
"An unmet need existed in the treatment of moderate-to-severe psoriasis," says Dr. Langley, professor and director of research in the Division of Dermatology.
"The effect is rapid," says Dr. Langley.
"We saw 50 per cent improvement within three weeks."
It was initially thought that psoriasis was caused by too much cell turnover in the skin.
Instead, recent research has shown that the body's immune system releases small proteins that spark the development of the disease.
"In people with psoriasis, their IL-17A protein levels are six times higher than in normal skin," says Dr. Langley.
"When IL-17A levels are too high, it signals more skin cells to grow.
And too many skin cells cause thickened skin and plaque to develop."
"Identifying that secukinumab blocks IL-17A is one of the most - if not the most - impressive results that we've seen in psoriasis research," says Dr. Langley.
"Nova Scotia has one of the highest rates of melanoma in the country," says Dr. Richard Langley, professor and director of research in Dalhousie Medical School's Division of Dermatology.
Dr. Langley and Dr. Peter Hull, professor and head of the Division of Clinical Dermatology and Cutaneous Science at Dalhousie Medical School, will lead the study.
"We want to know if the Verisante machine is capable of detecting early-stage melanoma as effectively as a human specialist can," notes Dr. Langley, explaining that, while melanoma is 100 per cent curable if detected and removed before it has spread, survival rates drop sharply when this is not the case.
"We can see already that the Shaws' gift is transformational," says Dr. Langley.
Mednet - CME, CHE | Psoriasis Update: Focus on the Biologics in Moderate to Severe Disease
According to Dr. Richard Langley, Associate Professor of Medicine, Dalhousie University, Halifax, Nova Scotia, early findings have shown good response rates with adalimumab, noting that use of this compound in psoriasis appears promising.
The following question-and-answer session was conducted with Dr. Wayne Gulliver, Chairman, Division of Dermatology, Memorial University of Newfoundland, St. Johnâ€™s; and Dr. Richard Langley, Associate Professor of Medicine, Dalhousie University, Halifax, during the scientific sessions.
Dr. Langley: You can vaccinate patients with a killed vaccine and still achieve an adequate humoral response but not with a live vaccine.
Live vaccines are contraindicated in this setting.