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This profile was last updated on 3/1/15  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Renier J. Brentjens

Wrong Dr. Renier J. Brentjens?

Cancer Specialist

Phone: (212) ***-****  HQ Phone
Sloan-Kettering Cancer Center
1275 York Avenue
New York , New York 10021
United States


Employment History

Board Memberships and Affiliations

  • Member of Laboratory


  • MD
    SUNY Buffalo
160 Total References
Web References
Renier J. Brentjens, cancer ... [cached]
Renier J. Brentjens, cancer specialist at Memorial Sloan-Kettering Cancer Center, and his team treated f...
Juno Therapeutics Takes On Novartis With CAR-T Cell Therapy | Biotech Strategy Blog [cached]
Juno Therapeutics takes on Novartis and seeks to revolutionize the treatment of blood cancers - an interview with Renier Brentjens
One of the benefits of attending the American Society of Hematology (ASH) annual meeting that finished earlier this week in New Orleans is the opportunity to talk to experts who are at the forefront of their field.
Picture of Dr Renier Brentjens, Director of Cell Therapeutics, Memorial Sloan-Kettering Cancer Center
Renier Brentjens, MD PhD, is Director of Cell Therapeutics at Memorial Sloan-Kettering Cancer Center (MSKCC) and one of the scientific founders of Juno Therapeutics (Juno), a start-up company that recently raised $120M in Series A financing.
Subscribers to premium content can login to read my interview with Renier Brentjens and listen to audio excerpts from what was a fascinating conversation about a new immunotherapy that has the potential to revolutionize hematology.
Alexandria Summit: Oncology 2013 [cached]
Renier J. Brentjens, MD, PhD
Associate Member, Associate Attending Physician, Leukemia Service & Chief, Cellular Therapeutics Center, Memorial Sloan-Kettering Cancer Center
Renier J. Brentjens, MD, PhD, obtained an MD and PhD (microbiology) from SUNY Buffalo, completed residency in medicine at Yale New Haven Hospital, and a medical oncology fellowship at Memorial Sloan-Kettering Cancer Center (MSKCC). Currently, Dr. Brentjens is an associate member on the faculty at MSKCC and an attending physician on the leukemia service.
As a medical oncology fellow during his training at MSKCC, Dr. Brentjens initiated the initial pre-clinical studies demonstrating the potential clinical application of autologous T cells genetically modified to target the CD19 antigen through the retroviral gene transfer of artificial T cell receptors termed chimeric antigen receptors (CARs). Following completion of his medical oncology training, Dr. Brentjens became the principal investigator (PI) of his own laboratory.
As a PI, Dr. Brentjens successfully translated these studies to the clinical setting, treating patients with relapsed CD19+ tumors including chronic lymphocytic leukemia (CLL) and B cell acute lymphoblastic leukemia (B-ALL). Ongoing pre-clinical research in the laboratory is focused on the further development of CAR modified T cells, designed to overcome the hostile immunosuppressive tumor microenvironment through the generation of "armored CAR T cells" currently being translated to the clinical setting as second-generation CAR modified T cell clinical trials. Additionally, work in Dr. Brentjens' lab has expanded this CAR technology to target additional tumor antigens expressed on other tumors, including targeting the MUC-16 antigen expressed on ovarian carcinomas as well as the more ubiquitous WT-1 tumor associated antigen.
ASH Meeting on Lymphoma Biology [cached]
Renier J. Brentjens, MD, PhD Memorial Sloan-Kettering Cancer Center, New York, NY
Renier J. Brentjens, MD, PhD ... [cached]
Renier J. Brentjens, MD, PhD Director, Cellular Therapeutics Center, Associate Attending Physician, Leukemia Service Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
Drs. Park and Brentjens indicated no relevant conflict of interest. back to top
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