"The greatest bottleneck in my work is the ability to handle molecules in such a way that does not produce false positives or negatives," says Ozgur Sahin, a junior fellow at Harvard's Rowland Institute.
uses an AFM to measure intermolecular forces and provides that data to other scientists.
"We can't be sure whether what we're measuring comes from a single molecule or a group of molecules," he
came across a technology he
believes has potential to help researchers work with greater precision, improving the accuracy of nanoscale measurements.
The material is a nanoparticle coating called NanoCone that is made by Westlake Village, Calif.-based Nanogea, Inc.
NanoCone is used to coat AFM probes and the substrates on which samples are placed with cone-shaped nanoparticles that lift and separate individual molecules so they can more easily and accurately be measured.
discovered Nanogea research papers describing their technology while he
was searching the Web for new technologies that might improve the accuracy and efficiency of his
Biological molecules have a recognition capability, Sahin
says, adding, "They know to which molecules they want to bind, but our ability to handle these individual molecules is limited by our surface chemistry.