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Wrong Owen Pornillos?

Owen Wilbert Pornillos

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Background Information

Employment History

Assistant Professor

University of Virginia

Scientific Associate

The Scripps Research Institute

Web References (2 Total References)

ACA 2011 Meeting - Program Details [cached]

Owen Wilbert Pornillos, Univ. of Virginia

"Anything that destabilizes the capsid, ... [cached]

"Anything that destabilizes the capsid, either by inhibiting assembly or accelerating disassembly should attenuate or even kill the virus," says Owen Pornillos, an investigator in Yeager's lab and first author of the Cell paper.

That study provided the first glimpse of how CA proteins are arranged in the capsid. (The first author of the 2007 article was Barbie Ganser-Pornillos, Owen Pornillos' wife, who was also involved in the current study.)
To overcome the problem, Pornillos and Yeager turned to molecular biology.
"The curvature of the capsid is not constant," says Pornillos.
In addition to Yeager, Pornillos, and Ganser-Pornillos of Scripps Research and the University of Virginia, co-authors of the paper "X-Ray Structures of the Hexameric Building Block of the HIV Capsid," include Yuanzi Hua and C. David Stout at Scripps Research, and Brian N. Kelly, Frank G. Whitby, Wesley I. Sundquist, and Christopher P. Hill at the University of Utah School of Medicine.

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