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This profile was last updated on 3/18/14  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Nitin Kumar Saksena

Wrong Dr. Nitin Kumar Saksena?
Phone: +61 * **** ****  HQ Phone
Email: n***@***.au
University of Sydney
44-78 Rosehill Street
Redfern, New South Wales 2016
Australia

 
Background

Employment History

Board Memberships and Affiliations

  • Visiting Fellow Scientist
    Pasteur Institute
19 Total References
Web References
Search Our People
www.wmi.org.au, 20 Aug 2014 [cached]
Dr Nitin Saksena - Virus Research
Westmead Millennium Institute: Dr Nitin Saksena
www.wmi.usyd.edu.au, 19 Sept 2010 [cached]
Dr Nitin Saksena | Saksena, Dr Nitin
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Dr Nitin Saksena
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Dr Nitin Saksena
Retroviral Genetics Research Group
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Dr Saksena trained as a microbiologist during his Ph.D studies in Medical Microbiology/Pathology .
In 1985 he was awarded a post-doctoral fellowship to work at the Pasteur Institute, Paris. Since then he has continued to work in the area of retroviruses and has specialized in both biology and molecular biology of HIV, HTLV and simian SIV and STLV. n 1990, he was a visiting Fellow scientist at the Pasteur Institute. Following his sojourn at the Pasteur Institute, he also worked at the State University of New York (SUNY), Syracuse,USA, as an Assistant Professor. Thus he trained with the mentors who discovered HIV-1 (Francoise Barre-Sinoussi at the Pasteur Institute) and HTLV (Bernard J. Poiesz at the SUNY, Syracuse).
Dr Saksena is currently the Head of the Retroviral Genetics Laboratory at the Westmead Millennium Institute and a Senior Research Fellow at the Department of Medicine, University of Sydney, Sydney.
Research Interests
Dr Saksena has the following research interests:
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Lau KA Bin Wang, Adeeba Kamarulzaman, Kee-Peng Ng and Nitin K. Saksena. Continuous crossover(s) events of HIV-1 CRF01_AE and B subtype strains in Malaysia: Evidence of Rapid and Extensive HIV-1 Evolution in the Region. Current HIV Research, 6(2) 108-16; 2008. [Abstract]
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Jing Qin Wu, Wayne B. Dyer, Jeremy Chrisp, Larissa Belov, Bin Wang and Nitin K. Saksena.
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Arriaga, M, Carr, J, Li, P, Wang, B, Saksena, N. Interaction between HIV-1 and APOBEC3 sub-family of proteins.
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Steain, M, Wang, B, Saksena, N. Analysis of HIV-1 sequences vertically transmitted to infants in Kisumu, Kenya.
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Potter, S, Lemey, P, Dyer, W, Sullivan, J, Chew, C, Vandamme, A, Dwyer, D, Saksena, N. Genetic analyses reveal structured HIV-1 populations in serially sampled T lymphocytes of patients receiving HAART.
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Gray, L, Churchill, M, Keane, N, Sterjovski, J, Ellett, A, Purcell, D, Poumbourios, P, Kol, C, Wang, B, Saksena, N, Wesselingh, S, Price, P, French, M, Gabuzda, D, Gorry, P. Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5 Delta 32 allele.
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Verity, E, Williams, L, Haddad, D, Choy, V, O'Loughlin, C, Chatfield, C, Saksena, N, Cunningham, A, Gelder, F, McPhee, D. Broad neutralization and complement-mediated lysis of HIV-1 by (PE)HRG214, a novel caprine anti-HIV-1 polyclonal antibody. Aids. 2006; 20:505-515 [Abstract]
Shah, M, Smit, T, Morgello, S, Tourtellotte, W, Gelman, B, Brew, B, Saksena, N. Env gp120 sequence analysis of HIV type 1 strains from diverse areas of the brain shows preponderance of CCR5 usage. AIDS research and human retroviruses. 2006; 22:177-81 [Abstract]
2005
Steain, M, Wang, B, Yang, C, Shi, Y, Nahlen, B, Lal, R, Saksena, N. HIV type 1 sequence diversity and dual infections in Kenya.
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Cali, L, Wang, B, Mikhail, M, Gill, M, Beckthold, B, Salemi, M, Jans, D, Piller, S, Saksena, N. Evidence for host-driven selection of the HIV type 1 vpr gene in vivo during HIV disease progression in a transfusion-acquired cohort.
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Chew, C, Potter, S, Wang, B, Wang, Y, Shaw, C, Dwyer, D, Saksena, N. Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART.
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Mikhail, M, Wang, B, Lemey, P, Beckholdt, B, Vandamme, A, Gill, M, Saksena, N. Full-length HIV type 1 genome analysis showing evidence for HIV type 1 transmission from a nonprogressor to two recipients who progressed to AIDS.
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Wang, B, Potter, S, Lin, Y, Cunningham, A, Dwyer, D, Su, Y, Ma, X, Hou, Y, Saksena, N. Rapid and sensitive detection of severe acute respiratory syndrome coronavirus by rolling circle amplification.
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Saksena, N, Smit, T. HAART & the molecular biology of AIDS dementia complex. The Indian journal of medical research. 2005; 121:256-69 [Abstract]
Saksena, N, Wang, B, Steain, M, Yang, R, Zhang, L. Snapshot of HIV pathogenesis in China.
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Mikhail, M, Wang, B, Lemey, P, Beckthold, B, Vandamme, A, Gill, M, Saksena, N. Role of viral evolutionary rate in HIV-1 disease progression in a linked cohort.
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Smit, T, Brew, B, Tourtellotte, W, Morgello, S, Gelman, B, Saksena, N. Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment. Journal of virology. 2004; 78:10133-48 [Abstract]
Potter, S, Lemey, P, Achaz, G, Chew, C, Vandamme, A, Dwyer, D, Saksena, N. HIV-1 compartmentalization in diverse leukocyte populations during antiretroviral therapy. Journal of leukocyte biology. 2004; 76:562-70 [Abstract]
Potter, S, Chew, C, Steain, M, Dwyer, D, Saksena, N. Obstacles to successful antiretroviral treatment of HIV-1 infection: problems & perspectives. The Indian journal of medical research. 2004; 119:217-37 [Abstract]
Zaunders, J, Dyer, W, Wang, B, Munier, M, Miranda-Saksena, M, Newton, R, Moore, J, Mackay, C, Cooper, D, Saksena, N, Kelleher, A. Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection.
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Otake, K, Omoto, S, Yamamoto, T, Okuyama, H, Okada, H, Okada, N, Kawai, M, Saksena, N, Fujii, Y. HIV-1 Nef protein in the nucleus influences adipogenesis as well as viral transcription through the peroxisome proliferator-activated receptors. AIDS (London, England). 2004; 18:189-98 [Abstract]
Omoto, S, Ito, M, Tsutsumi, Y, Ichikawa, Y, Okuyama, H, Brisibe, E, Saksena, N, Fujii, Y. HIV-1 nef suppression by virally encoded microRNA. Retrovirology. 2004; 1:44 [Abstract]
2003
Lemey, P, Salemi, M, Wang, B, Duffy, M, Hall, W, Saksena, N, Vandamme, A. Site stripping based on likelihood ratio reduction is a useful tool fo evaluate the impact of non-clock-like behavior on viral phylogenetic reconstructions.
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Lemey, P, Pybus, O, Wang, B, Saksena, N, Salemi, M, Vandamme, A. Tracing the origin and history of the HIV-2 epidemic.
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Potter, S, Dwyer, D, Saksena, N. Diffential cellular distribution of HIV-1 drug resistance in vivo: evidence for infection of CD8+ T cells during HAART. Virology. 2003; 305:339-352
Wang, B, Mikhail, M, Dyer, W, Zaunders, J, Kelleher, A, Saksena, N. First demonstration of a lack of viral sequence evolution in a nonprogressor, defining replication-incompetent HIV-1 infection.
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Wang, B, Dyer, W, Zaunders, J, Mikhail, M, Sullivan, J, Williams, L, Haddad, D, Harris, G, Holt, J, Cooper, D, Miranda-Saksena, M, Boadle, R, Kelleher, A, Saksena, N. Comprehensive analyses of a unique HIV-1-infected nonprogressor reveal a complex association of immunobiological mechanisms in the context of replication-incompetent infection.
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Birch, M, Learmont, J, Dyer, W, Deacon, N, Zaunders, J, Saksena, N, Cunningham, A, Mills, J, Sullivan, J. An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC).
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Smit, T, Wang, B, Ng, T, Osborne, R, Brew, B, Saksena, N. Varied Tropism of HIV-1 Isolates Derived from Different Regions of Adult Brain Cortex Discriminate between Patients with and without AIDS Dementia Complex (ADC); Evidence for Neurotropic HIV Variants.
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Wang, Y, Dyer, W, Workman, C, Wang, B, Sullivan, J, Saksena, N. Molecular evidence for drug-induced compartmentalization of HIV-1 quasispecies in a patient with periodic changes to HAART.
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Haddad, D, Birch, C, Middleton, T, Dwyer, D, Cunningham, A, Saksena, N. Evidence for late stage compartmentalization of HIV-1 resistance mutations between lymph node and peripheral blood mononuclear cells. AIDS. 2000; 14:2273-2281
Wang, B, Lal, R, Dwyer, D, Miranda Held, M, Boadle, R, Cunningham, A, Saksena, N. Molecular and biological interactions between two HIV-1 strains from a coinfected patient reveal the first evidence in favor of viral synergism.
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Wang, Y, Dyer, W, Workman, C, Wang, B, Sullivan, J, Saksena, N. Molecular evidence for drug-induced compartmentalization of HIV-1 quasispecies in a patient with periodic changes to HAART.
Nitin Saksena, head of the ...
forums.poz.com, 6 Aug 2008 [cached]
Nitin Saksena, head of the retroviral genetics division at Westmead Millennium Institute's Center for Virus Research in Sydney, Australia, said the study needs to be confirmed by other research, and it has limitations, such as the small number of patients involved. It's important to consider that "elite controllers" are quite different from each other, Saksena added.
Dr Nitin Saksena
www.wmi.usyd.edu.au, 6 Jan 2012 [cached]
Dr Nitin Saksena
...
Internet > Our People > Dr Nitin Saksena
...
Dr Nitin Saksena
Dr Saksena trained as a microbiologist during his PhD studies in Medical Microbiology/Pathology .
In 1985 he was awarded a post-doctoral fellowship to work at the Pasteur Institute, Paris. Since then he has continued to work in the area of retroviruses and has specialized in both biology and molecular biology of HIV, HTLV and simian SIV and STLV. In 1990, he was a visiting Fellow scientist at the Pasteur Institute. Following his sojourn at the Pasteur Institute, he also worked at the State University of New York (SUNY), Syracuse, USA, as an Assistant Professor. Thus he trained with the mentors who discovered HIV-1 (Francoise Barre-Sinoussi at the Pasteur Institute) and HTLV (Bernard J. Poiesz at the SUNY, Syracuse).
Dr Saksena is currently the Head of the WMI Retroviral Genetics Group and a Senior Research Fellow at the Department of Medicine, University of Sydney.
| Dr Nitin Saksena, Head of ...
www.wmrf.org.au, 25 Aug 2011 [cached]
| Dr Nitin Saksena, Head of the WMI Retroviral Genetics Group and a Senior Research Fellow at the Department of Medicine, University of Sydney
Neurodegenerative diseases, which include all forms of dementias, are destined to become the next great health crusade over the next several decades globally. Neurodegeneration is caused by the loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's and viral mediated dementias occur as a result of neurodegenerative processes. Nitin will discuss many similarities between viral and non-viral mediated neurodegenerative diseases and what these results offer for therapeutic advances.
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