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This profile was last updated on 4/25/15  and contains information from public web pages and contributions from the ZoomInfo community.

Prof. Mitch Dowsett

Wrong Prof. Mitch Dowsett?

Professor

Phone: +44 ** **** ****  HQ Phone
Email: m***@***.uk
Breakthrough Breast Cancer
3Rd Floor Weston House 246 High Holborn
High Holborn , London WC1V 7EX
United Kingdom

Company Description: Breakthrough Breast Cancer is a charity committed to fighting breast cancer through research and awareness and has established the UK's first dedicated breast...   more
Background

Employment History

Board Memberships and Affiliations

Education

  • BSc
    Imperial College
  • PhD
    Chester Beatty Cancer Research Institute at London University
185 Total References
Web References
Endocrinology | Breakthrough Breast Cancer research
www.breakthroughresearch.org.uk, 25 April 2015 [cached]
The newly founded Endocrinology Team, which was developed by the joining of the Translational Research Team (Mitch Dowsett) and the Molecular Endocrinology Team (Mitch Dowsett & Lesley-Ann Martin) to form a concerted effort, to generate increased knowledge on the important mechanisms of response and resistance specifically to oestrogen deprivation and most particularly to AIs by making use of large clinical data sets and in vitro laboratory models for hypothesis driven study.
...
Professor Mitch Dowsett
Professor Mitch Dowsett
Professor Mitch Dowsett received his Ph.D. from Chester Beatty Cancer Research Institute at London University. He is currently Head of the Academic Department of Biochemistry at the Royal Marsden Hospital, Professor of Biochemical Endocrinology at the Institute of Cancer Research, and Professor of Translational Research in the Breakthrough Breast Cancer Centre, London.
Professor Dowsett's research focuses almost exclusively on breast cancer and predominantly on hormonal aspects of the disease and biomarkers of response. He has been closely involved with the clinical development of aromatase inhibitors and the establishment of Ki67 as an intermediate marker of treatment benefit. His work has focused mainly on the assessment of biomarkers in large phase III clinical trials. He has written widely on this, including on the general potential and limitation of such studies.
Professor Dowsett has authored over 500 published papers related to breast cancer, and was the 2007 William L McGuire Memorial Lecturer. He is a member of the Executive Board of the Breast International Group (BIG), and sits on the Executive/Steering Committees of several clinical trials. He chairs the translational research committees for the ATAC and HERA clinical trials and is co-PI of the national POETIC trial of preoperative endocrine therapy.
He is the founding chairman of the NCRI Biomarker and Imaging Clinical Study Group and is a member of the NCRI Breast Cancer Study Group. He was an author of both the UK and the ASCO/CAP guidelines for HER2 diagnostics. He is the international member of the ASCO/CAP Steering Committee for ER/PgR IHC guidelines.
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Professor Mitch Dowsett
Breakthrough scientist Professor ...
www.breakthrough.org.uk, 26 Mar 2015 [cached]
Breakthrough scientist Professor Mitch Dowsett Breakthrough scientist Professor Mitch Dowsett
Professor Mitch Dowsett Professor Dowsett helps introduce new treatments and fine-tunes those already available. Read more about Professor Mitch Dowsett
Board of Directors | About BIG | Breast International Group (BIG)
www.breastinternationalgroup.org, 5 July 2010 [cached]
Mitchell Dowsett, BSc, PhD (Vice-secretarty)
...
Mitchell Dowsett, BSc, PhD Vice-secretary
Mitchell Dowsett is Head of the Academic Department of Biochemistry at the Royal Marsden Hospital, Professor of Biochemical Endocrinology at the Institute of Cancer Research and Professor in the Breakthrough Breast Cancer Research Centre, London, UK.
His major research interests are the endocrinology of breast cancer and biomarkers of response and resistance to treatment. He has a research staff of about 25 and has published over 430 papers on breast cancer. He is chairman of TransATAC, co-chairman of TransHERA, a member of the executive committee of HERA and a member of the steering committee of several other trials. He is co-principal investigator of the POETIC trial a translational research trial in 4000 patients. He currently chairs the planning committee of the Aromatase Inhibitor Overview Group. He chaired the advisory committee on HER2 testing in the UK and has co-ordinated a number of quality appraisal studies of HER2 analysis. Most recently he has served as a member of the ASCO/CAP task force on HER2 testing and has been invited to take a similar role on the upcoming task force on ER/PgR testing.
He is the founding chairman of the National Cancer Research Institute Translational Clinical Study Group with the remit of co-ordinating and enhancing translational research across the UK's cancer clinical trial portfolio. He is past chairman of the British Breast Group.
He lectures widely at international meetings and gave the 2007 William McGuire Memorial Lecturer at San Antonio. In 2006 he created an international web-based opinion survey to identify the translational breast cancer research questions considered most important to answer.
Mitchell Dowsett, BSc, ...
www.bigagainstbreastcancer.org, 10 May 2014 [cached]
Mitchell Dowsett, BSc, PhD
...
Mitchell Dowsett, BSc, PhD
Mitchell Dowsett is Head of the Academic Department of Biochemistry at the Royal Marsden Hospital, Professor of Biochemical Endocrinology at the Institute of Cancer Research and Professor in the Breakthrough Breast Cancer Research Centre, London, UK.
His major research interests are the endocrinology of breast cancer and biomarkers of response and resistance to treatment. He has a research staff of about 25 and has published over 430 papers on breast cancer. He is chairman of TransATAC, co-chairman of TransHERA, a member of the executive committee of HERA and a member of the steering committee of several other trials. He is co-principal investigator of the POETIC trial, a translational research trial in 4000 patients. He currently chairs the planning committee of the Aromatase Inhibitor Overview Group.
He chaired the advisory committee on HER2 testing in the UK and has co-ordinated a number of quality appraisal studies of HER2 analysis.
He has served as a member and steering committee member, respectively, of the ASCO/CAP task forces on HER2 and ER/PgR testing and is a member of the Special Awards committee of ASCO.
He is the founding chairman of the National Cancer Research Institute Biomarker and Imaging Clinical Study Group with the remit of co-ordinating and enhancing translational research across the UK's cancer clinical trial portfolio. He is past chairman of the British Breast Group. He is a Senior Investigator of the UK National Institute of Health Research.
He lectures widely at international meetings and was awarded the 2007 William McGuire Memorial Lectureship at San Antonio.
Breast Cancer Campaign - Previous Scientific Advisory Board members
www.breastcancercampaign.org, 30 Mar 2011 [cached]
Professor Mitchell Dowsett, Ph.D. Professor Mitchell Dowsett is Professor of Biochemical Endocrinology (1994) and was the Head of the Academic Department of Biochemistry at the Institute of Cancer Research and Royal Marsden NHS Trust (1990). He received his BSc. (Zoology) from Imperial College at London University and his Ph.D. from Chester Beatty Cancer Research Institute at London University.
Professor Dowsett is an active member of numerous cancer committees, a member of the Steering Committees of four chemoprevention trials, and Co-Chairman of the pathology sub-committee of the ATAC trial; the largest trial of adjuvant therapy conducted in breast cancer. He is Co-Chair of the Translational Research Committee of the HERA Trial and has recently become Chairman of the NTRAC Translational Research Committee that aims to markedly enhance the value of translational research in the UK's national portfolio of phase III clinical trials in cancer. He is author of more than 350 published papers related to breast cancer.
Professor Dowsett's research focuses exclusively on breast cancer and predominantly on hormonal aspects of the disease. He has been closely involved with the development of aromatase inhibitors over a period of 20 years.
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