SITraN, as part of its ongoing research strategy to develop its capacity for world leading neurodegenerative research in Sheffield, has embarked on a fundraising initiative in partnership with Mr Jonathan M L Stone, Founding Patron of the Sheffield Instit...
Professor Mimoun AzzouzProfessor of Translational Neuroscience, University of Sheffield and Head of Gene Therapy Laboratory and ERC Advanced Investigator, Sheffield Institute for Translational Neuroscience
Professor Mimoun Azzouz from SITraN at the University of Sheffield has been presented with a €2.5m award from the European Research Council (ERC) for his groundbreaking work in gene therapy for neurodegenerative diseases.
Professor Azzouz, Chair of Translational Neuroscience at the Sheffield Institute for Translational Neuroscience (SITraN), has been recognised with the prestigious and highly competitive ERC Advanced Investigator Award, a great distinction in European biomedical research.
The outstanding achievement allows Professor Azzouz and his team to expand the horizon of translational research at SITraN and develop tools for efficient, safe and selective delivery of therapies to the central nervous system (CNS) to treat neurological disorders.
His research team will also undertake studies in order to gain a better understanding of disease mechanisms at the molecular and cellular levels in two devastating neurodegenerative diseases, Spinal Muscular Atrophy (SMA) and Motor Neuron Disease (MND).
Professor Azzouz said: "I am delighted to be presented with this prestigious award.
This is a wonderful achievement which will enhance the research capability and profile of my research team as well as neuroscience research in Sheffield".
"This award now offers me a platform to reinforce my, and SITRaN's, European and international leadership in the field of gene therapy for neurodegenerative disease."
Professor Azzouz and his team utilise viral based gene transfer systems both for research and gene therapy applications.
Such viral systems have included lentiviruses and adeno-associated vectors.
His research focuses on developing new therapeutic strategies for Motor Neuron Diseases and Parkinson's disease.
Award winner Professor Mimoun Azzouz
Sheffield's groundbreaking clinical research is awarded over £3.1 million
Professor Mimoun Azzouz, Chair of Translational Neuroscience at the Sheffield Institute of Translational Neuroscience (SITraN), has been investigating a gene therapy for SMA for over twelve years.
Recent research data has provided promising proof of concept for Resagen, a potential gene therapy product for patients with SMA.
Professor Azzouz is encouraged by recent results: "The data is promising, and now we need to take it to the next step.