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This profile was last updated on 10/13/13  and contains information from public web pages and contributions from the ZoomInfo community.

Prof. Mimoun Azzouz

Wrong Prof. Mimoun Azzouz?

Head of Gene Therapy Laboratory a...

Phone: +44 *** *** ****  HQ Phone
Email: m***@***.uk
Sheffield Institute for Translational Neuroscience
385A Glossop Road
Sheffield, South Yorkshire S10 2HQ
United Kingdom

Company Description: SITraN, as part of its ongoing research strategy to develop its capacity for world leading neurodegenerative research in Sheffield, has embarked on a fundraising...   more
Background

Employment History

Education

  • Biology and Neuroscience
    University of Rabat
  • Master , Neuroscience
    University of Marseille
  • PhD , Neuropharmacology
    University Louis Pasteur
27 Total References
Web References
SITraN - The University of Sheffield
sitran.dept.shef.ac.uk, 13 Oct 2013 [cached]
» Professor Mimoun Azzouz
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Professor Mimoun Azzouz Professor of Translational Neuroscience, University of Sheffield and Head of Gene Therapy Laboratory and ERC Advanced Investigator, Sheffield Institute for Translational Neuroscience
SITraN - The University of Sheffield
sitran.dept.shef.ac.uk, 13 Oct 2013 [cached]
Professor Mimoun Azzouz from SITraN at the University of Sheffield has been presented with a €2.5m award from the European Research Council (ERC) for his groundbreaking work in gene therapy for neurodegenerative diseases.
Professor Azzouz, Chair of Translational Neuroscience at the Sheffield Institute for Translational Neuroscience (SITraN), has been recognised with the prestigious and highly competitive ERC Advanced Investigator Award, a great distinction in European biomedical research.
The outstanding achievement allows Professor Azzouz and his team to expand the horizon of translational research at SITraN and develop tools for efficient, safe and selective delivery of therapies to the central nervous system (CNS) to treat neurological disorders.
His research team will also undertake studies in order to gain a better understanding of disease mechanisms at the molecular and cellular levels in two devastating neurodegenerative diseases, Spinal Muscular Atrophy (SMA) and Motor Neuron Disease (MND).
Professor Azzouz said: "I am delighted to be presented with this prestigious award. This is a wonderful achievement which will enhance the research capability and profile of my research team as well as neuroscience research in Sheffield".
"This award now offers me a platform to reinforce my, and SITRaN's, European and international leadership in the field of gene therapy for neurodegenerative disease."
Professor Azzouz and his team utilise viral based gene transfer systems both for research and gene therapy applications. Such viral systems have included lentiviruses and adeno-associated vectors. His research focuses on developing new therapeutic strategies for Motor Neuron Diseases and Parkinson's disease.
Award winner Professor Mimoun Azzouz
Sheffield's groundbreaking clinical research is awarded over £3.1 million
Neuro Staff Contacts - Staff - Neuroscience - The University of Sheffield
www.sheffield.ac.uk, 25 June 2013 [cached]
Professor Mimoun Azzouz Chair of Translational Neuroscience m.azzouz@sheffield.ac.uk +44(0)114 2222238
SITraN - The University of Sheffield
sitran.dept.shef.ac.uk, 13 Oct 2013 [cached]
Professor Mimoun Azzouz | more SITraN - The University of Sheffield
The University of Sheffield
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Professor Azzouz has a long-standing interest in developing gene therapy approaches for neurodegenerative diseases. Azzouz' team utilises viral based gene transfer systems both for research and gene therapy applications. Such viral systems have included lentiviruses and adeno-associated vectors. His research focuses on developing new therapeutic strategies for motor neuron diseases (ALS and SMA) and Parkinson's disease. He also collaborates with other groups looking at new experimental approaches to treatment of Alzheimer's disease and multiple sclerosis. Members of the team are also investigating molecular pathways and signalling of motor neuron death associated with ALS and SMA.
Background Information
Professor Azzouz graduated in Biology and Neuroscience from the University of Rabat in 1993. He obtained a Master in Neuroscience with 1st Class Honours from the University of Marseille in 1994. In 1997 he was awarded a PhD in Neuropharmacology at the University Louis Pasteur in Strasbourg. He then worked as post doctoral scientist at the Gene Therapy Center in Lausanne, Switzerland from 1997 to 2000. He was recruited in 2000 by Oxford BioMedica Ltd as Senior Scientist then appointed as Director of Neurobiology in 2003. He was also a visiting scientist at Oxford University between 2000 and 2005. In 2006 he was appointed Professor of Translational Neuroscience at the University of Sheffield.
Current Research
Professor Azzouz is currently using his expertise in neuroscience and gene therapy to develop therapies for motor neuron diseases. He is a Chair of Translational Neuroscience at the University of Sheffield and formerly Director of Neurobiology at Oxford BioMedica Ltd. Since his appointment to the Chair of Translational Neuroscience, in 2006, he assembled an excellent research team and has been successful in attracting an array of scientific funding from prestigious national and international funding bodies. His current research in the newly established gene therapy laboratory is focused on four major objectives:
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Professor Azzouz has an excellent publication track record. He published papers in high profile and prestigious journals such as Nature, Nature Medicine, Nature Neuroscience, Science Translational Medicine. Azzouz has led the field internationally in developing and evaluating gene therapy approaches using viral vectors, with the potential for exciting new therapeutic approaches in neurodegenerative diseases. Gene therapy in models of Parkinson's disease (PD) is already translating into human clinical trials and a new SMN replacement strategy is currently entering clinical development for SMA patients.
He has been successful in attracting an array of scientific awards including the prestigious ERC Advanced Investigator Award. This award is a top level EU ad hominem award acknowledging his pre-eminence in European biomedical research. Professor Azzouz is advisor for pharmaceutical companies (BioMarin Pharmaceutical Inc, Oxford BioMedica Ltd). He is member of scientific advisory panel for various funding bodies such as the Medical Research Council (MRC), the French Muscular Dystrophy Association and The Research Council of Norway.
Professor Azzouz's research is funded by the Medical Research Council, Jennifer Trust, EPSRC, AFM, SMA Europe, ERC Advanced Award and MRC DPFS.
Neuro Staff Contacts - Staff - Neuroscience - The University of Sheffield
shef.ac.uk, 1 Aug 2012 [cached]
Professor Mimoun Azzouz Professor of Translational Neuroscience m.azzouz@sheffield.ac.uk +44(0)114 2222238
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