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2016-09-22T00:00:00.000Z

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Wrong Michele Tagliati?

Dr. Michele Tagliati

Professor and Vice Chairman, Department of Neurology - Director, Movement Disorders

Cedars-Sinai Medical Center

HQ Phone: (310) 855-5000

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Cedars-Sinai Medical Center

8700 Beverly Blvd.

Los Angeles, California 90048

United States

Company Description

Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quali ... more

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Background Information

Affiliations

Member of the Editorial Board
Journal of Parkinson's Disease

Scientific Advisory Board Member
The Bachmann-Strauss Dystonia & Parkinson Foundation Inc

Member
Central Park Track Club

Division Chief of Movement Disorders
Mount Sinai Hospital

Faculty Member
Albert Einstein College of Medicine

Education

American Board of Psychiatry and Neurology

MD

medical degree

University of Rome

medical degree

University of Rome , Italy

Web References (185 Total References)


Our partners - www.stop-pd.org

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Dr. Michele Tagliati, MD Dr. Tagliati, is Director of the Movement Disorders Program in the Department of Neurology at Cedars-Sinai Medical Center. Dr. Tagliati is one of the world's pioneers in deep brain stimulation (DBS) and is an authority on the use of botulinum toxin injection therapy in the control of involuntary muscle contractions. Dr. Tagliati previously served as Division Chief of Movement Disorders at Mount Sinai Medical Center in New York. He specializes in all forms of movement disorders, including tremor, dystonia, chorea, tics and Parkinson's disease. He often serves in leadership and advisory roles with such organizations as the American Academy of Neurology, the Movement Disorder Society, the National Institutes of Health, the Parkinson Study Group, the National Parkinson Foundation, the Dystonia Medical Research Foundation and the Parkinson Alliance. Dr. Tagliati has lectured internationally on deep brain stimulation management and currently serves as director of the educational course on DBS programming at the American Academy of Neurology annual meetings. he author of more than 80 articles in peer-reviewed publications, Dr. Tagliati has written more than 20 chapters in medical textbooks. He also co-authored the book "Parkinson's Disease for Dummies,"and is currently a member of the editorial board of Journal of Parkinson's Disease. Dr. Tagliati earned his medical degree from the University of Rome, Italy, where he also completed a residency in neurology and a fellowship in clinical neurophysiology. He completed an internship and second neurology residency at Mount Sinai. He then completed a fellowship in movement disorders at Beth Israel Medical Center in New York.


Record the motion symptoms of disorders like Parkinsons Disease

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In an interview with Medical Device Daily, Michele Tagliati, director of the movement disorders program at Cedars-Sinai Medical Center (Los Angeles) has described the PKG™ as a "potential game changer for treating Parkinson's."

Tagliati, who is about to undertake a 50-patient study with the PKG™, found the device useful in providing an objective recording of movement symptoms not only for himself and his colleagues, but also for their patients. One of his patients noted how easy the PKG™ was to use and found it of benefit in recording his symptoms as "it was able to describe what I was trying to describe."


Led by Michele Tagliati, ...

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Led by Michele Tagliati, director of Cedars-Sinai Medical Center's Movement Disorders Program, Los Angeles, USA, the study identified variables that affect impedance-resistance in circuits that affect intensity and wavelength of electrical current. Doctors who specialise in programming deep brain stimulation devices fine-tune voltage, frequency and other parameters for each patient; deviations from these settings may have the potential to alter patient outcomes.

"Deep brain stimulation devices are currently designed to deliver constant, steady voltage, and we believe consistency and reliability are critical in providing therapeutic stimulation. But we found that we cannot take impedance stability for granted over the long term," said Tagliati, the senior author of a journal article that reveals the study's findings.
"Doctors with experience in deep brain stimulation management can easily make adjustments to compensate for these fluctuations, and future devices may do so automatically," he added.


Alternatives to neurotech therapies and diagnostics, deep brain stimulation (DBS) BIS monitoring, Aspect Medical Covidien, Cedars-Sinai

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Although the article points out the percentage of inappropriate referrals has declined compared to a similar study conducted in 2004, physicians still often refer patients for DBS therapy before other treatment options have been exhausted or because they have unrealistically high expectations for it, according to Michele Tagliati, director of the Movement Disorders Program at Cedars-Sinai's Department of Neurology and senior author of the paper.


Michele Tagliati, MD, ...

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Michele Tagliati, MD, director of the Movement Disorders Program in the Department of Neurology at Cedars-Sinai, said the device could be a game-changer for the treatment of patients with advanced Parkinson's disease by providing an objective record of movement fluctuations.

Tagliati said such information can enhance doctors' understanding of the nature and progression of the disorder, a brain disorder, which progressively affects a person's ability to control body movements. Up to 60,000 new cases are diagnosed each year.
The small gadget - the size, weight and shape of a wristwatch - also vibrates to remind patients to press a button indicating that they have taken medication prescribed to reduce their body movements.
"This technology could help us as physicians better inform our patients of treatment options, such as when to have an aggressive therapy like deep brain stimulation," Tagliati said. "A more refined approach to treating the symptoms of the disease will ultimately lead to a better quality of life for our patients."
Currently, one of the biggest challenges neurologists face when managing Parkinson's patients is making treatment decisions based on relatively brief patient interactions and subjective patient reports about symptoms.
"It's virtually impossible to make a well-informed treatment plan based on how patients feel they have been doing in the last three months because often they don't remember," Tagliati said. "The PKG device provides a quantitative way to monitor and understand the fluctuations of movements in our patients when they are not in the office."
Tagliati and his colleague, Echo Tan, MD, have sought to more fully understand the disease through their research. After the US Food and Drug Administration cleared the watch-like device in late 2014, Tagliati and Tan launched a 60-patient clinical trial to study its effectiveness.
Tan said the preliminary findings have been valuable. She recalled one patient who said his medication stopped working after three hours even though the report generated by the watch device showed that the drug hadn't worked at all.

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