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Dr. Michele Tagliati

Professor and Vice Chairman, Department of Neurology - Director, Movement Disorders

Cedars-Sinai Medical Center

HQ Phone: (310) 423-8000

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Cedars-Sinai Medical Center

8700 Beverly Blvd.

Los Angeles, California 90048

United States

Company Description

Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quali ... more

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Background Information

Employment History

Vice Chairman, Department of Neurology

Medical Group Of Beverly Hills Inc

Member, Doctor Bressman's Movement Disorders Group

Beth Israel Medical Center


Chief of Movement Disorders
Mount Sinai School of Medicine

Member of the Editorial Board
Journal of Parkinson's Disease

Scientific Advisory Board Member
The Bachmann-Strauss Dystonia & Parkinson Foundation Inc

Central Park Track Club

Faculty Member
Albert Einstein College of Medicine


American Board of Psychiatry and Neurology


medical degree

University of Rome

medical degree

University of Rome , Italy

Web References (185 Total References)

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Michele Tagliati, MD

Michele Tagliati, MD

Neurology Department Expert Team - Cedars-Sinai [cached]

Michele Tagliati, MD

Michele Tagliati, MD
Medical Director, Movement Disorders Program
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Michele Tagliati, MD

Michele Tagliati, MD
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Led by Michele Tagliati, director of Cedars-Sinai Medical Center's Movement Disorders Program, Los Angeles, USA, the study identified variables that affect impedance-resistance in circuits that affect intensity and wavelength of electrical current. Doctors who specialise in programming deep brain stimulation devices fine-tune voltage, frequency and other parameters for each patient; deviations from these settings may have the potential to alter patient outcomes.

"Deep brain stimulation devices are currently designed to deliver constant, steady voltage, and we believe consistency and reliability are critical in providing therapeutic stimulation. But we found that we cannot take impedance stability for granted over the long term," said Tagliati, the senior author of a journal article that reveals the study's findings.
"Doctors with experience in deep brain stimulation management can easily make adjustments to compensate for these fluctuations, and future devices may do so automatically," he added.

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Michele Tagliati, MD, director of the Movement Disorders Program in the Department of Neurology at Cedars-Sinai, said the device could be a game-changer for the treatment of patients with advanced Parkinson's disease by providing an objective record of movement fluctuations.

Tagliati said such information can enhance doctors' understanding of the nature and progression of the disorder, a brain disorder, which progressively affects a person's ability to control body movements. Up to 60,000 new cases are diagnosed each year.
The small gadget - the size, weight and shape of a wristwatch - also vibrates to remind patients to press a button indicating that they have taken medication prescribed to reduce their body movements.
"This technology could help us as physicians better inform our patients of treatment options, such as when to have an aggressive therapy like deep brain stimulation," Tagliati said. "A more refined approach to treating the symptoms of the disease will ultimately lead to a better quality of life for our patients."
Currently, one of the biggest challenges neurologists face when managing Parkinson's patients is making treatment decisions based on relatively brief patient interactions and subjective patient reports about symptoms.
"It's virtually impossible to make a well-informed treatment plan based on how patients feel they have been doing in the last three months because often they don't remember," Tagliati said. "The PKG device provides a quantitative way to monitor and understand the fluctuations of movements in our patients when they are not in the office."
Tagliati and his colleague, Echo Tan, MD, have sought to more fully understand the disease through their research. After the US Food and Drug Administration cleared the watch-like device in late 2014, Tagliati and Tan launched a 60-patient clinical trial to study its effectiveness.
Tan said the preliminary findings have been valuable. She recalled one patient who said his medication stopped working after three hours even though the report generated by the watch device showed that the drug hadn't worked at all.

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