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8700 Beverly Blvd.
Los Angeles, California 90048
Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quali ... more
Vice Chairman, Department of Neurology
Member, Doctor Bressman's Movement Disorders Group
Chief of Movement Disorders
Mount Sinai School of Medicine
Member of the Editorial Board
Journal of Parkinson's Disease
Scientific Advisory Board Member
The Bachmann-Strauss Dystonia & Parkinson Foundation Inc
Central Park Track Club
Albert Einstein College of Medicine
American Board of Psychiatry and Neurology
University of Rome
University of Rome , Italy
Neurology Department Expert Team - Cedars-Sinai
"Deep brain stimulation devices are currently designed to deliver constant, steady voltage, and we believe consistency and reliability are critical in providing therapeutic stimulation.
But we found that we cannot take impedance stability for granted over the long term," said Tagliati, the senior author of a journal article that reveals the study's findings.
"Doctors with experience in deep brain stimulation management can easily make adjustments to compensate for these fluctuations, and future devices may do so automatically,"
Tagliati said such information can enhance doctors' understanding of the nature and progression of the disorder, a brain disorder, which progressively affects a person's ability to control body movements.
Up to 60,000 new cases are diagnosed each year.
The small gadget - the size, weight and shape of a wristwatch - also vibrates to remind patients to press a button indicating that they have taken medication prescribed to reduce their body movements.
"This technology could help us as physicians better inform our patients of treatment options, such as when to have an aggressive therapy like deep brain stimulation," Tagliati said.
"A more refined approach to treating the symptoms of the disease will ultimately lead to a better quality of life for our patients."
Currently, one of the biggest challenges neurologists face when managing Parkinson's patients is making treatment decisions based on relatively brief patient interactions and subjective patient reports about symptoms.
"It's virtually impossible to make a well-informed treatment plan based on how patients feel they have been doing in the last three months because often they don't remember," Tagliati said.
"The PKG device provides a quantitative way to monitor and understand the fluctuations of movements in our patients when they are not in the office."
Ferrari Club of America
International Training Centre of the ILO
Team Management Systems Inc
Menarini Group Companies