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This profile was last updated on 8/18/15  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Michael T. Riebe PhD

Wrong Dr. Michael T. Riebe PhD?

Vice President, Pharmaceutical De...

Phone: (650) ***-****  HQ Phone
Local Address:  Sarasota , Florida , United States
Pearl Therapeutics , Inc.
200 Saginaw Drive
Redwood City , California 94063
United States

Company Description: Pearl was founded in 2006, with a mission to develop differentiated therapeutics for respiratory disease conditions prevalent worldwide, including chronic...   more

Employment History

Board Memberships and Affiliations

  • Steering Committee Member
    Nasal Technology Focus Group


  • Ph.D.
  • B.A. degree , chemistry
    Kalamazoo College
17 Total References
Web References
New Leaf Venture Partners :: a leader in healthcare technology venture investing, 17 Jan 2013 [cached]
REDWOOD CITY, CALIF., January 17, 2013 - Pearl Therapeutics Inc. today announced that Michael Riebe, Ph.D. has joined Pearl Therapeutics as vice president, pharmaceutical development and research, effective immediately.
Speaking for the management and board of directors, we welcome Mike to the Pearl team."
Prior to joining Pearl Therapeutics, Dr. Riebe was vice president of research and development at iCeutica where he led development of the Company's pipeline of pain, oncology and respiratory products. Prior to iCeutica, Dr. Riebe held various roles at Merck, most recently senior scientific director in respiratory product development; and at RTI, an independent, nonprofit research and development organization. From 1990 through 2003, Dr. Riebe held several positions in respiratory product development at GlaxoSmithKline and its predecessor, Glaxo Wellcome, where he led project teams responsible for pharmaceutical development of Serevent®, Ventolin® HFA, and Seretide®/Advair® HFA. Dr. Riebe received his B.A. degree in chemistry from Kalamazoo College and his Ph.D. in analytical chemistry from the University of Wisconsin - Madison. He has served in numerous leadership positions within the American Chemical Society and the American Association for Pharmaceutical Scientists, including as chairman of the AAPS Inhalation and Nasal Technology Focus Group.
Pearl Therapeutics hires ... [cached]
Pearl Therapeutics hires Michael Riebe | Pearl Therapeutics hires Michael Riebe | . . . Read more
Pearl Therapeutics hires Michael Riebe | Pearl Therapeutics hires Michael Riebe | . . . Read more
Pearl Therapeutics hires Michael Riebe Jan 172013
Pearl Therapeutics, which is developing several inhaled drugs, has announced that it has hired Michael Riebe as VP, Pharmaceutical Development and Research, effective immediately. Riebe, a past chair and current steering committee member of the AAPS Inhalation and Nasal Technology Focus Group, was most recently VP of Research and Development at iCeutica and previously worked in inhaled drug development at Merck and at Glaxo.
Speaking for the management and board of directors, we welcome Mike to the Pearl team."
Inc. (Whitehouse Station, NJ), which ..., 1 July 2007 [cached]
Inc. (Whitehouse Station, NJ), which currently has no drug products delivered via inhalation technology, Michael Riebe is director for inhalation delivery technology in addition to being the company's director for pharmaceutical research and development.One of his primary goals is to enable pharmaceutical development of inhalation drugs at Merck.
Riebe says that, among pharmaceutical companies, a common misconception is that developing pulmonary-delivery products is quite a bit more expensive than developing oral products."The CMC [chemistry, manufacturing and controls] is more," he said, "but that's a small percentage of product development costs."CMC costs are driven by the added complexity of pulmonary delivery, integrating an inhalation device with a dose of the drug to be delivered.
He also advises caution in manufacturing operations due to the purity and consistency required of drugs for pulmonary delivery."Sometimes vendors [of delivery devices] change things," says Riebe."When a component manufacturer changes something about its manufacturing process,for example, changing the base resin used in a polymer that goes into a valve,that can slip through the change control process."
Clinical costs,one of the largest expenses of bringing a drug to market,are the same whether a drug is formulated as oral, pulmonary or injected, he notes.FDA approvals, however, take significantly longer for pulmonary delivery drugs than for oral drugs."That has been improving over recent years, but still takes longer," he says."There's not a lot of guidance from FDA yet."
Reibe says pulmonary delivery is most often thought of as being used for local delivery to treat respiratory disease."It's a misconception that it's not for systemic delivery," he says.
NCACS Local Section Officers, 11 Aug 2015 [cached]
M. T. Riebe GlaxoSmithKline Inc. 3030 Cornwallis Rd. Research Triangle Park NC 27709 (919) 483-3608 (W)
Contact: M. T. Riebe
Management - iCeutica: Evolving Drug Development, 21 Oct 2012 [cached]
Dr Mike Riebe PhD
Vice President, Research and Development
Dr Riebe is responsible for SoluMatrix™ technology development and all CMC activities including GMP manufacturing of iCeutica's products. He is a former Senior Scientific Director with Merck and Executive Director with GSK, and is recognized internationally as an expert in respiratory product development. Dr Riebe has led a number of cross functional international development teams responsible for the launch of oral and respiratory products in a variety of therapeutic areas.
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