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Wrong Mark Ashwell?

Dr. Mark A. Ashwell

Head of Chemistry

Nimbus Therapeutics LLC

HQ Phone: (857) 999-2009

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Nimbus Therapeutics LLC

784 Memorial Drive Suite 100

Cambridge, Massachusetts 02139

United States

Company Description

Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Massachusetts (USA). It is pioneering the application of computational chemistry to design breakthroughs for the treatment of substantial and underserved human diseases. The compan ... more

Find other employees at this company (16)

Background Information

Employment History

Vice President, Head of Chemistry

ArQule , Inc.

Research Leader



Vice President, Medicinal Chemistry
Cambridge Healthtech Institute



bachelor's degree


University of Birmingham


organic chemistry

University of Birmingham

Web References (20 Total References)

Mark Ashwell, ... [cached]

Mark Ashwell, ph.d.

Head of Chemistry
Mark Ashwell, Ph.D.
Head of Chemistry
Dr. Mark Ashwell is Head of Chemistry at Nimbus. He has worked in R&D in both biotech and pharma for more than 25 years, with experience advancing research portfolios across multiple target classes and therapeutic areas. Mark specializes in the fields of drug discovery research, technology utilization, portfolio creation and management, and business development. Before joining Nimbus, he was Principal Consultant at Ashwell Consulting Group, where he provided strategic counsel to biotech, pharma, academia and R&D service industries in a number of areas including oncology, medicinal chemistry, structure-based drug discovery, intellectual property creation and atypical modes of target inhibition.
Prior to this, Mark was Vice President, Head of Chemistry at ArQule Inc., where he built and managed a cross functional team responsible for multiple research collaborations, which significantly contributed to the delivery of eight INDs into clinical development. Mark was an inventor and key driver of the ArQule Kinase Inhibition Technology Platform (AKIP™), which was leveraged to establish strategic R&D partnerships with global pharmaceutical companies, including Daiichi-Sankyo.
Mark completed two postdoctoral research fellowships, worked as an NIH-funded World Health Organization consultant, and received his B.Sc. in Chemistry and his Ph.D. in Organic Chemistry from the University of Birmingham in the U.K. He has published over 30 peer-reviewed research papers and is listed as an inventor on 50 U.S.-granted patents and over 30 international filings.

Nimbus Appoints Mark ... [cached]

Nimbus Appoints Mark Ashwell, Ph.D., as Head of Chemistry Nimbus

Nimbus Appoints Mark Ashwell, Ph.D., as Head of Chemistry
CAMBRIDGE, Mass. - Jan 5, 2017 - Nimbus Therapeutics, a biotechnology company applying deep computational chemistry expertise throughout drug discovery and development, today announced that Mark Ashwell, Ph.D., has joined the company as the Head of Chemistry. The appointment further expands Nimbus' core development capabilities and bolsters the senior leadership team as the company works to advance multiple promising pipeline candidates toward clinical-stage development. As Head of Chemistry, Dr. Ashwell's responsibilities include maximizing Nimbus' unique relationship with founding partner Schrödinger while also integrating new technologies and collaborators into Nimbus' cutting-edge platform and approach to drug discovery, helping to realize Nimbus' vision of creating breakthroughs by design while tackling tough targets like Tyk2, STING and others in the Nimbus pipeline.
An accomplished R&D leader, Dr. Ashwell served as the long-time Head of Chemistry at ArQule, where he led eight drug candidates from discovery and early development into clinical-stage testing, in cancer and rare diseases. Furthermore, he was an inventor of the ArQule Kinase Inhibition Technology Platform, the company's discovery engine, which yielded product opportunities that led to productive R&D partnerships with global pharmaceutical companies.
"Mark is a terrific addition to our high-performing team, whose technical expertise and entrepreneurial vision will help drive our continued success discovering and developing novel therapies for some of the most promising targets in drug development," said Don Nicholson, Ph.D., Chief Executive Officer at Nimbus.
"Building on the strong foundation laid by our founding Head of Chemistry, Dr. Ron Wester, Mark will work alongside our Chief Scientific Officer, Dr. Rosana Kapeller, and Head of Preclinical Research and Early Development, Dr. Wes Westlin, to accelerate our next breakthroughs in discovery."
Nimbus also announced today that Dr. Wester has assumed the role of senior emeritus advisor and will remain with Nimbus to support Dr. Ashwell.
In addition to his experience at ArQule, Dr. Ashwell has served as a consultant to numerous drug development teams in industry and academia across a wide range of areas that included oncology drug development, medicinal chemistry, structure-based drug discovery and intellectual property creation. Earlier in his career, he worked as a researcher at Wyeth and as an NIH-funded World Health Organization consultant.
Dr. Ashwell holds a doctorate in organic chemistry and a bachelor's degree in chemistry, both from the University of Birmingham in the U.K., and completed two postdoctoral research fellowships. He has published over 30 peer-reviewed research papers and is listed as an inventor on 50 U.S.-granted patents and more than 30 international filings.

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Mark Ashwell Vice President Chemistry

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Dr. Mark Ashwell, Director of Chemistry, Arqule Inc.

Dr. Mark Ashwell, Director of Medicinal Chemistry, Arqule, Inc.

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Nimbus Appoints Mark Ashwell, Ph.D., as Head of Chemistry

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