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This profile was last updated on 10/12/14  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Lee B. Riley

Wrong Dr. Lee B. Riley?

Medical Director of Cancer Center

Local Address: Bethlehem, Pennsylvania, United States
St. Luke's Hospital
 
Background

Employment History

  • Medical Director, Oncology Services
    St. Luke's Hospital
  • Medical Director of Oncology and Director of Surgical Research
    St. Luke's Hospital
  • Owner
    Cancer Immunotherpies, LLC

Board Memberships and Affiliations

  • Board Member
    Cancer Support Community

Education

  • MD
  • PhD
  • medical degree
    University of Texas Medical School at Houston
  • Doctor of Philosophy degree , immunology
    University of Texas Graduate School of Biomedical Sciences
128 Total References
Web References
St. Luke's - Executive and Medical Leadership
www.slhn.org, 12 Oct 2014 [cached]
Dr. Lee Riley
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Lee Riley, MD, PhD Medical Director of Oncology
St. Luke's surgical oncologist Lee ...
bethlehem.slhn.org, 19 Aug 2014 [cached]
St. Luke's surgical oncologist Lee B. Riley, MD, PhD, medical director of St. Luke's Cancer Center, will get his head and beard shaved to experience the hair loss his patients with breast cancer often endure.
"Losing hair is one of the things women undergoing treatment for breast cancer fear most," says Dr. Riley. "For years I've told patients their hair will grow back, but I'm willing to learn what this one side effect is like. I just thought this would mean more to these women if I put myself in their shoes and experienced what they endure."
Dr. Riley will go completely bald and have his beard shaved intentionally in front of viewers throughout the Lehigh Valley who tune into WFMZ-TV Channel 69 news Thursday, June 12, at 8 am. The experience also will serve to raise some of the monies needed to further his breast cancer vaccine research. Dr. Riley is one of a select group of doctors involved with breast cancer vaccine research nationwide.
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If $10,000 or more is raised, Dr. Riley will agree to have his eyebrows shaved in front of the camera as well.
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"We've received support from several local groups, including Dr. Riley's patients, St. Luke's employees, teachers from the Bethlehem, Easton and Quakertown school districts, and members of local groups such as Harley Owners of the Lehigh Valley and Pirates in Paradise, Lehigh Valley chapter," she says. "The Quakertown Kiwanis has even chartered a bus to come out for Wednesday to support the girls. They'll have their meeting on the bus on the way over and come out to participate."
The winning team will be announced Thursday morning on Channel 69. The biggest tippers and Dr. Riley's patients will be in attendance and get a chance to shave a section of hair along with the winning team.
About the vaccine research Dr. Riley is convinced his breast cancer research holds promise. "There are at least 30 different vaccines being tested right now in women with advanced breast cancer," says the physician. "The strategy behind this one is different. We are comparing different immune stimulants to identify which stimulant, or which combination of several stimulants provides the strongest vaccine. We are studying this in women with early breast cancer - a time when we believe the vaccine will be the most effective."
A week before the tumor and lymph gland are removed surgically, the tumor is "killed" with radiofrequency ablation, a technique similar to microwaves, according to Dr. Riley. This technique is performed under local anesthetic. Currently, the immune stimulating drug GM-CSF is injected into the killed tumor and a vaccine is made inside the tumor.
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"We have known for a long time which immune stimulants work best in mice, but it's not clear that they work the same in patients," says Dr. Riley.
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The ultimate goal of the vaccine is to generate a long-term durable response, according to Dr. Riley. "Today women with breast cancer have surgery to remove the tumor; chemotherapy and radiation are also part of the protocol to limit the risk of the disease coming back," he says. "Still nearly 30 percent of women with breast cancer will have a recurrence. Ultimately, we hope to demonstrate a marked decrease of cancer recurrence in women who have had this vaccine therapy."
A positive result for breast cancer patients could mean positive implications for other solid tumors and even lymphomas in the long term as well, according to Dr. Riley.
A hairless, newly coiffed Dr. Riley will go out in public to attend the grand opening celebration of the St. Luke's Regional Breast Center in Center Valley the evening of June 12.
"We are excited about this new ...
bethlehem.slhn.org, 10 Nov 2010 [cached]
"We are excited about this new opportunity and for the joy it will bring to our patients," says Lee B. Riley, MD, PhD, FACS, Medical Director, Oncology Services, St. Luke's Hospital & Health Network.
St. Luke's - Gene-Chip Technology
www.slhn.org, 10 Jan 2011 [cached]
Above, Dr. Riley holds the newest Illumina chip being used in the St. Luke's Cancer Research
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in this field, according to Dr. Riley.
Bethlehem, PA (1/10/2011) - Recently, a very unique and exciting piece of equipment called the IlluminaBeadArray Reader was purchased for St. Luke's Cancer Research Lab. It's an innovative technology that will position St. Luke's as the region's leading hospital involved with translational cancer research, according to Lee B. Riley, MD, PhD, FACS, Medical Director of Oncology and Director of Surgical Research for St. Luke's Hospital & Health Network.
The key is gene-chip technology. This fully confocal microarray scanning system works in concert with IlluminaBeadChips, giving researchers the ability to scan Infinium and GoldenGate Genotyping products. "Amazingly, the one-inch gene-chip can evaluate the expression of all 25,000 human genes from a sample," says Dr. Riley.
The completion of the human genome project changed the research world over the last decade. "Now this equipment, coupled with gene-chip technology, is changing the clinical world as well," says Dr. Riley. "Importantly, the knowledge gained from genomic research can lead to scientific discoveries and clinical applications that may ultimately reduce cancer incidence and improve survivorship."
Sampling the tumor bank for genomic clues
This past year, St. Luke's piloted a program to acquire and preserve nucleic acids (both DNA and RNA) from patients' tumors. "This limited tumor bank is now being extended to a larger set of patients," says Dr. Riley. "Additionally, we have started extracting RNA from cancer samples stored in paraffin. Because St. Luke's preserves cancer samples for 10 years, we have access to the 'genomic finger prints' of an estimated 20,000 cancers."
The potential to extract genomic info rmation from over 20,000 cancers and 10-year cancer-outcome data, including survival and recurrence data, provides St. Luke's with an immense research resource. "Over the past six months, we have demonstrated we can extract and preserve the genetic material from fresh and preserved cancer tissue," says Dr. Riley. "We are now poised to utilize the gene-chip equipment."
St. Luke's is a community facility and follow-up clinical info rmation has been superb. "It's worth noting St. Luke's cancer program received the highest honor from the American College of Surgeons for the quality of their clinical follow-up," says Dr. Riley.
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"Now that this equipment is on site, we will be able to save considerably by not outsourcing our genomic material at the current cost of $2,000 per patient," says Dr. Riley.
Cancer Support Community - Greater Lehigh Valley - About Us
www.cancersupportglv.org, 7 May 2014 [cached]
Lee B. Riley, MD, PhD
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Lee Riley, MD, PhD
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