Dr. Kursad Turksen, Phd, is a basic researcher with a cross-appointment to the Division of Dermatology.
is actively involved in research involving claudin-6 and keratinization.
team co-discovered a molecule called claudin-6 that plays a key role in the development and function of skin cells.
is also investigating the role of claudin-6 in the differentiation of embryonic stem cells.
Depending on various signals, these stem cells can form any tissue in the body.
It turns out that claudin-6 may play a key role in directing stem cells to begin differentiating into skin cells.
Understanding this pathway could lead to new drugs that would promote the regeneration of skin in wound and burn victims.
As the development of skin is closely tied to the development of hair follicles, this research also has implications for developing new treatments for hair loss.
Dr. Turksen is an expert in isolating and culturing stem cells, and he recently edited the following books on this topic: Embryonic Stem Cell Protocols I; Embryonic Stem Cell Protocols II; Human Embryonic Stem Cell Protocols.
Dr. Turksen is a Senior Scientist in the Hormones, Growth, and Development Program at the OHRI, as well as an Associate Professor at the University of Ottawa.
research is supported by the Canadian Institutes of Health Research