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Dr. Kennedy F. Shortridge

Wrong Dr. Kennedy F. Shortridge?


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Scientific Discovery November 2005 - March 2006 - Page 1, 9 Dec 2013 [cached]
Professor Dr. Ken F.S. Shortridge
Emeritus Professor Kennedy Shortridge is a pioneer in researching the potentially deadly disease "bird flu " , leading to the establishment of preparation systems to deal with future outbreaks.
Professor Shortridge, a University of Queensland graduate, moved to Hong Kong in 1972 after completing his PhD at The University of London in 1971, commencing studies in 1975 into how avian influenza viruses spread to humans.
His studies drew attention to the importance of domestic poultry and pigs as the most likely sources of virus for humans.
His findings, including the hypothesis in 1982 of southern China's role as an epicentre for the emergence of pandemic influenza viruses, enabled the development of surveillance and preparation systems for future outbreaks.
Dr. Shortridge receiving a life-Fellowship from WIF Member Dr. Tsui Lap-Chee, Vice-Chancellor of Hong Kong University October 2005
Professor Shortridge's work was crucial to the early detection of the H5N1 "bird flu " outbreak in 1997, potentially saving incalculable lives.
Professor Shortridge recently retired from HKU`s Department of Microbiology.
Professor Shortridge's vital work earned him a Prince Mahidol Award in Public Health in 1999 for services to the global community toward the control of "bird flu ".
Like the vast majority of other ..., 1 Jan 2009 [cached]
Like the vast majority of other cases outside of Mexico so far, it is mild, but virologist Kennedy Shortridge warns that is no reason for complacency. He says that the farther the virus spreads, the more chance it will mix, or reassort, with other flu viruses in circulation and turn into something more lethal. "The prospects for change [in the virus] are considerable and worrying," he says.
Shortridge is a professor emeritus at the University of Hong Kong, where he led investigations into the initial emergence of H5N1 avian influenza in 1997, when it killed six of the 18 people it infected. The city squelched that outbreak by slaughtering all 1.4 million chickens and ducks in the territory. H5N1 re-emerged in 2003 and since then has claimed 257 lives while devastating poultry flocks throughout much of Asia and parts of Africa. Shortridge has long advocated global cooperation in the surveillance of circulating flu viruses to spot emerging new strains so that public health officials could plan a response and drug companies could get a head start on making vaccines.
He was among the first to suggest that pigs might act as mixing vessels for new combinations of viruses. And the swine flu, now spreading from Mexico, "fits into the mixing vessel hypothesis," he says.
Analysis of flu specimens by Canada's National Microbiology Laboratory in Winnipeg and at the U.S. Centers for Disease Control and Prevention in Atlanta, Georgia, have found that the virus is made up of pieces of human, swine, and avian viruses from North America, Europe, and Asia. The mixture "gives an order of complexity we really don't understand at this point," Shortridge says.
In particular, he says he is concerned that this patched-together virus might not be stable and could easily reassort with other viruses encountered in a human or animal host. The virus has now spread to Asia, where the H5N1 virus is circulating. Shortridge says there are strains of human H1N1 in circulation in many areas that are resistant to Tamiflu, the drug of choice for treating the disease in humans. He speculates that swapping one or more genes among these viruses could result in a virus that is more pathogenic or more easily passed from person to person or both.
As a precaution, Shortridge suggests sequencing as many viral samples as quickly as possible to watch for any telltale changes in the virus--a massive job requiring worldwide cooperation. He says such cooperation seems to be off to a good start, thanks to the experience of dealing with the 2003 SARS crisis and recent efforts to prepare for an influenza pandemic. "There is a success story in this in that the world is alert" to the possibility of a pandemic, he says. Still, he adds, even better collaboration and communication will be required in the face of a threat that could change overnight.
Chickens in the News - Page 11 - - Rocking T Ranch and Poultry Farm, 6 Feb 2002 [cached]
"It will need one little chance ... and this could give rise to a serious virus," Dr. Ken Shortridge, a microbiologist at the University of Hong Kong who is heading an investigation into the flu outbreak.
But that threat is there if it does happen to go to the right type of reassortment (mutation)," Ken Shortridge, who is studying the virus, said on Hong Kong RTHK radio. "It will need one little chance ... and this could give rise to a serious virus."
Earlier, Shortridge told the daily South China Morning Post that the bird flu outbreak came from the same family of viruses that mutated into the deadly human strain in 1997.
Shortridge said the danger came from the speed with which the virus was mutating in Hong Kong's aquatic bird population. It could become a risk to humans but so far this was not the case.
The government has said the virus had not been identified as yet, but Shortridge said it was from the H5N1 goose family from which the 1997 strain that killed humans emerged. It is still the Guangdong goose family (of H5N1) but it is moving away from the Guangdong virus of 1996," the parent strain of the 1997 flu, he said. "The way the virus is behaving now, we are seeing it undergo many, many of what we call reassortment, swapping genes with many other viruses quickly," he told RTHK on radio.
Feed E-news January 2006, 1 Jan 2006 [cached]
Last week, Dr Kennedy Shortridge, a virologist at the University of Hong Kong who has researched the H5N1 virus in China since it first killed humans in 1997, warned against blaming the spread of the deadly H5N1 virus on migratory birds.He told a conference in Singapore, organized by the Lancet medical journal, that the movement of poultry around the world could play a major role.Dr Shortridge advised researchers not to rush to blame migratory birds, but to look for the disease also along routes of human transportation, including by rail, road, and water.For more, see
by Kennedy Shortridge, PhD, ..., 19 Mar 2007 [cached]
by Kennedy Shortridge, PhD, DSc(Hon), CBiol, FIBiol
Professor Emeritus Kennedy Shortridge
Professor Emeritus Kennedy Shortridge
Professor Emeritus Kennedy Shortridge is credited for having first discovered the H5N1 virus in Asia.As chair of the Department of Microbiology at the University of Hong Kong, Dr. Shortridge led the world's first fight against the virus.For his pioneering work studying flu viruses, which spans over three decades, he was awarded the highly prestigious Prince Mahidol Award in Public Health, considered the "Nobel Prize of Asia."
Kennedy F. Shortridge
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