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2016-11-25T00:00:00.000Z

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Dr. Joseph Cheriyan

Associate Lecturer

University of Cambridge

Direct Phone: +44 **** ******       

Email: j***@***.uk

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University of Cambridge

Downing Street

Cambridge, Cambridgeshire CB2 3EG

United Kingdom

Company Description

The Cambridge Canadian Studies Initiative (CCSI) was founded in 2004, creating a new focal point for Canadian Studies at the University of Cambridge. The CCSI was widely welcomed as reestablishing an institutional presence for Canadian Studies at Cambri ... more

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Background Information

Employment History

Director

Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust

Affiliations

Secretary
Addenbrooke's Hospital

Vice Chair, Cambridge Central Ethics Committee
Health Research Authority

Vice Chair
Cambridge BRC

Web References (80 Total References)


Dr Joseph Cheriyan - EMIT

emit.medschl.cam.ac.uk [cached]

Home/Department of Medicine/Experimental Medicine and Immunotherapeutics (EMIT)/People/Investigators/ Dr Joseph Cheriyan

...
Dr Joseph Cheriyan
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Dr Cheriyan Associate Lecturer in Medicine, University of Cambridge
Consultant Physician and Clinical Pharmacologist, Cambridge University Hospitals NHS Foundation Trust.
Director of the Cardiovascular Clinical Trials Office, Cambridge University Hospitals NHS Foundation Trust.
Vice Chair, Cambridge Central Ethics Committee, Health Research Authority.
Email:jc403@cam.ac.uk
Tel: 01223 256653
...
Dr Joseph Cheriyan


'Tomato pill’ improves function of blood vessels - Experimental Medicine and Immunotherapeutics (EMIT)

emit.medschl.cam.ac.uk [cached]

Dr Joseph Cheriyan, consultant clinical pharmacologist & physician at Addenbrooke's Hospital and Associate Lecturer at the University of Cambridge, says: "There's a wealth of research that suggests that the Mediterranean diet - which includes lycopene found in tomatoes and other fruit as a component - is good for our cardiovascular health.

...
"We've shown quite clearly that lycopene improves the function of blood vessels in cardiovascular disease patients," adds Dr Cheriyan.


Dr Joseph Cheriyan, ...

iskandu.co.uk [cached]

Dr Joseph Cheriyan, consultant clinical pharmacologist and physician at Addenbrooke's Hospital and Associate Lecturer at the University of Cambridge, says: "There's a wealth of research that suggests that the Mediterranean diet - which includes lycopene found in tomatoes and other fruit as a component - is good for our cardiovascular health."

...
"We've shown quite clearly that lactolycopene in Ateronon improves the function of blood vessels in cardiovascular disease patients," adds Dr Cheriyan.


"There's a wealth of research that ...

www.lifeextension.com [cached]

"There's a wealth of research that suggests that the Mediterranean diet - which includes lycopene found in tomatoes and other fruit as a component - is good for our cardiovascular health," stated lead researcher Joseph Cheriyan, who is a consultant clinical pharmacologist and physician at Addenbrooke's Hospital and Associate Lecturer at the University of Cambridge. "But so far, it's been a mystery what the underlying mechanisms could be."

Endothelial dysfunction occurs when the inner lining of the blood vessels fails to dilate or constrict properly, and is believed to be involved in the development of atherosclerosis. In a double-blind trial, Dr Cheriyan and colleagues randomized 36 cardiovascular disease patients treated with statin drugs and an equal number of healthy control subjects to receive 7 milligrams oral lycopene per day or a placebo for two months. Forearm blood flow assessments of endothelium dependent and independent vasodilation, and basal nitric oxide synthase activity were conducted before and after treatment.
Endothelial-dependent vasodilation improved by 53% among those in the cardiovascular disease group who received lycopene. Although it averaged 30% lower in cardiovascular disease patients in comparison with healthy volunteers at the beginning of the study, by the end of the treatment period the endothelial-dependent vasodilation of participants with cardiovascular disease who received lycopene was comparable to that of the healthy subjects at the study's onset.
"We've shown quite clearly that lycopene improves the function of blood vessels in cardiovascular disease patients," Dr Cheriyan announced.


"There's a wealth of research that ...

www.lef.org [cached]

"There's a wealth of research that suggests that the Mediterranean diet - which includes lycopene found in tomatoes and other fruit as a component - is good for our cardiovascular health," stated lead researcher Joseph Cheriyan, who is a consultant clinical pharmacologist and physician at Addenbrooke's Hospital and Associate Lecturer at the University of Cambridge. "But so far, it's been a mystery what the underlying mechanisms could be."

Endothelial dysfunction occurs when the inner lining of the blood vessels fails to dilate or constrict properly, and is believed to be involved in the development of atherosclerosis. In a double-blind trial, Dr Cheriyan and colleagues randomized 36 cardiovascular disease patients treated with statin drugs and an equal number of healthy control subjects to receive 7 milligrams oral lycopene per day or a placebo for two months. Forearm blood flow assessments of endothelium dependent and independent vasodilation, and basal nitric oxide synthase activity were conducted before and after treatment.
Endothelial-dependent vasodilation improved by 53% among those in the cardiovascular disease group who received lycopene. Although it averaged 30% lower in cardiovascular disease patients in comparison with healthy volunteers at the beginning of the study, by the end of the treatment period the endothelial-dependent vasodilation of participants with cardiovascular disease who received lycopene was comparable to that of the healthy subjects at the study's onset.
"We've shown quite clearly that lycopene improves the function of blood vessels in cardiovascular disease patients," Dr Cheriyan announced.

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