Joanna Moncrieff, a senior lecturer of psychiatry at University College London in England, said this is the first analysis that links antidepressants to increased aggression in children.
"Doctors should be more cautious about prescribing to everyone and to young people especially, and regulators should put a warning on drug labels about aggressive behavior as well as suicide," said Moncrieff
, who wrote an accompanying editorial in the journal.
and Sharma agreed that the data from these drug trials need to be made publicly available, so independent researchers can assess the true risks of antidepressants.
said even that may not be enough to gain a complete understanding.
"Drug company information, even that supplied to regulators, is not reliable," she
SOURCES: Tarang Sharma, researcher, Nordic Cochrane Centre, University of Copenhagen, Denmark; Joanna Moncrieff, senior lecturer, psychiatry, University College London, England; Jan. 27, 2016, statement, Pharmaceutical Research and Manufacturers of America; Jan. 27, 2016, statement, Eli Lilly and Co.