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Wrong Jean Shih?

Dr. Jean Chen Shih

Associate Director, Health Sciences Campus

Daily Trojan

Direct Phone: (323) ***-****       

Email: j***@***.edu

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Daily Trojan

3601 Trousdale Parkway, Student Union 400 - MC 0895

Los Angeles, California 90089

United States

Company Description

The Daily Trojan, first published in 1912, has been providing the USC community with campus news and information for 100 years. Get the scoop on DT's history, developments and continuing legacy. ... more

Find other employees at this company (1,533)

Background Information

Employment History

Member, Staff

USC

Associate Director

University of Southern California

Senior Grant Specialist

City of Los Angeles - Mayor's Office

Affiliations

Board Member
Taiwanese American Foundation

Member
Science & Technology Advisory Group

Board Member
The Taiwanese American Organization

Vice President
Academia.edu

Education

Ph.D.

biochemistry

USC

Ph.D. degree

University of California , Riverside

bachelor degree

National Taiwan University

doctorate

biochemistry

University of Southern California

Web References (67 Total References)


About USC - Research - Shih

www.usc.edu [cached]

Jean Chen ShihUniversity Professor

...
In 2000, Jean Shih became the first woman to be awarded the Volwiler Research Achievement Award by the American Association of Colleges of Pharmacy (AACP).Shih has spent most of her career studying monoamine oxidase (MAO), a brain enzyme that affects mood, depression, addiction, blood pressure, the sleep-waking cycle and even Parkinson's disease.
In 2002, her research team became the first to model the enzyme's three-dimensional structure and to work out the key amino acids involved in its active sites.Their findings have aided efforts to design better antidepressants and to find treatments for Parkinson's.In 1988, Shih also located two genes on the X chromosome that control the production of two different forms of MAO, MAO-A and MAO-B.Through a series of experiments, she found that genetically engineered mice missing the MAO-A enzyme were unusually aggressive, while those missing both forms of the enzyme displayed both aggression and anxiety."This tells us that anxiety and aggression are regulated by similar neurotransmitter pathways," says Shih.
Shih joined the USC School of Pharmacy in 1974 as an assistant professor of pharmacy/biochemistry.For her groundbreaking research, Shih also has received two MERIT awards from the National Institutes of Health.


About USC - Research - Shih

www.usc.edu [cached]

Jean Chen ShihUniversity Professor

...
In 2000, Jean Shih became the first woman to be awarded the Volwiler Research Achievement Award by the American Association of Colleges of Pharmacy (AACP).Shih has spent most of her career studying monoamine oxidase (MAO), a brain enzyme that affects mood, depression, addiction, blood pressure, the sleep-waking cycle and even Parkinson's disease.
In 2002, her research team became the first to model the enzyme's three-dimensional structure and to work out the key amino acids involved in its active sites.Their findings have aided efforts to design better antidepressants and to find treatments for Parkinson's.In 1988, Shih also located two genes on the X chromosome that control the production of two different forms of MAO, MAO-A and MAO-B.Through a series of experiments, she found that genetically engineered mice missing the MAO-A enzyme were unusually aggressive, while those missing both forms of the enzyme displayed both aggression and anxiety."This tells us that anxiety and aggression are regulated by similar neurotransmitter pathways," says Shih.
Shih joined the USC School of Pharmacy in 1974 as an assistant professor of pharmacy/biochemistry.For her groundbreaking research, Shih also has received two MERIT awards from the National Institutes of Health.


MAO-A inhibitors may provide an unmet ...

www.futurity.org [cached]

MAO-A inhibitors may provide an unmet need in cancer treatment," says Jean C. Shih, a professor at the University of Southern California School of Pharmacy and co-corresponding author of the research published in the Journal of Clinical Investigation.

...
"We're happy to be able to translate our discoveries in basic research to clinical application," says Shih, who has studied MAO-A for 30 years and is also the director of the USC-Taiwan Center for Translational Research.


STOP CANCER - Funding Research | Finding Cures

www.stopcancer.org [cached]

Jeannie Chen, Ph.D. | Details STOP CANCER - Funding Research | Finding Cures

Join Our Mailing List:
...
Jeannie Chen, Ph.D.
...
Career Summary: Dr. Chen is Associate Professor of Biochemistry in the Zilkha Neurogenic Institute of USC Keck School of Medicine. She received her Ph.D. in biochemistry from USC in 1990. From 1991-1995 she undertook a postdoctoral research fellowship at California Institute of Technology (Pasadena), after which she joined the USC staff. Her multidisciplinary research efforts span the areas of signal transduction, vision, membranes and transport, and developmental biology. Year STOP CANCER Award was received: 1997 Seed Grant Description of research performed: Dr. Chen's lab is investigating the molecular mechanism of protein signaling in the photoreceptor cells of the retina of the eye, using mouse models. Results of research: Dr. Chen's team has been able to create models of retinal degeneration in mice, enabling study of the disease process at the molecular level. She believes this research can form the basis for designing new treatments for diseases of the eye.


STOP CANCER - Funding Research | Finding Cures

www.stopcancer.org [cached]

Jeannie Chen, Ph.D. Research Performed at: USC Norris Comprehensive Cancer Center

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