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Wrong Huda Akil?

Dr. Huda Akil

Direct Phone: (734) ***-****       

Email: a***@***.edu

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University of Michigan

1150 W. Medical Center Drive

Ann Arbor, Michigan 48109

United States

Company Description

The University of Michigan's College of Engineering is ranked among the top engineering schools in the country. At $180 million annually, its engineering research budget is one of the largest of any public university. Michigan Engineering is home to 11 ac ... more

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Background Information

Employment History


Molecular & Behavioral Neuroscience Institute at the University of Michigan

er and Past President

American College of Neuropsychopharmacology


Board Member
Hope for Depression Research Foundation

Honorary Board of Directors Member
IES Brain Research Foundation

Board Member
Coalition for the Life Sciences

National Academy of Sciences

Scientific Advisory Board Member
Depression Center

Scientific Advisory Board Member

Board Member
National Alliance for Research on Schizophrenia and Depression Inc

Society for Neuroscience

Board Member
Pritzker Neuropsychiatric Disorders Research Consortium

Board Member
Joint Steering Committee for Public Policy

American Association for the Advancement of Science

Member, Scientific Advisory Board
Brain & Behavior Research Foundation

Neuroscience Advisory Board Member
Gruber Foundation

Neuroscience Advisory Board Member
Peter and Patricia Gruber Foundation

Board Member

Institute of Medicine

Foundation Scientific Council

Neuroscience Steering Committee
Foundation for the National Institutes of Health Inc

American Academy of Art

American Academy of Arts and Sciences



University of Michigan


Mental Health Institute , University of Michigan


Columbia University


Institute of Medicine


Molecular and Behavioral Neuroscience Institute


National Academy of Sciences , online


Wayne State University


behavioral neuroscience

University of California , Los Angeles


MBNI Distinguished University



American University of Beirut , Lebanon

master's degrees


American University of Beirut , Lebanon

Web References (101 Total References)

Internal Advisory Board – Rat Genes [cached]

Huda Akil, PhD Co-Director and Research Professor, Molecular & Behavioral Neuroscience IInstitute Distinguished University Professor and Quarton Professor of Neurosciences, Department of Psychiatry University of Michigan, Ann Arbor

Science Advisory Council | OBI [cached]

Dr. Huda Akil, University of Michigan

IES Brain Research [cached]

Huda Akil, Ph.D., Co-Director & Research Professor, Mental Health Research Institute, Dept. of Psychiatry, Univ. of Michigan

Daily Gene Rhythms May Be Off in Depressed People – The Blue Room @ [cached]

But seeing whether that's true in the human brain is a lot tougher, said researcher Huda Akil.

If you want to look for daily rhythms in hormone activity, Akil said, you can take multiple blood samples from the same people over the course of 24 hours. You cannot, however, investigate the brain that way.
To get around the problem, Akil's team studied autopsied brain tissue from 89 people who had died at different times of day. That way, they could look at each person's gene activity at the time of death and search for differences from one individual to the next.
"Hundreds of genes emerged as having a rhythm based on the time of day," said Akil, a professor of neuroscience and psychiatry at the University of Michigan in Ann Arbor.
That rhythm was clear in brain tissue from the 55 people with no history of psychiatric disorders. Akil said her team was able to look at an individual's gene activity and correctly guess that person's time of death within an hour.
They could not, however, do that for the 34 individuals who were suffering from major depression at the time of death. Their gene activity patterns were too varied.
"This is very clear evidence that the 'clock' in the brain is disrupted in depression," Akil said.
Either way, Akil said she thinks the out-of-sync genes would feed people's symptoms. Think about how bad you feel, she said, when the body's normal rhythms are thrown off due to jet lag.
In the future, Akil said, the findings might help lead to new "biomarkers" for diagnosing depression or tracking how well the disorder is responding to treatment.
The findings might also help identify new "molecular targets" for depression treatment, Akil said.
Right now, antidepressant drugs target certain chemicals in the brain believed to contribute to depression - most famously, the mood-regulating chemical serotonin. But Akil said the new findings show that there are multiple things going wrong in the brain when a person has major depression.
"It's not only a serotonin imbalance," she said.

Board of Directors [cached]

Huda Akil, University of Michigan

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