"This is really an important observation," said H. Glenn Bohlen, a professor of cellular and integrative physiology at Indiana University Medical School, who wrote an accompanying editorial.
"It ties in information that high blood pressure and insulin resistance have the same cause, damage to receptors."
The function of proteases in rats and humans is the same, so what has been seen in the laboratory rats likely occurs in people."It probably happens in humans on a different scale," Bohlen
said."Rats live at a different metabolic rate, much faster than in people."
The newly reported studies might also help explain why antioxidants such as vitamins C and E help against inflammation, he
"The next approach probably would be to treat an inflammatory state," Bohlen
...SOURCES: Frank DeLano, Ph.D, research scientist, department of bioengineering, University of California, San Diego; H. Glenn Bohlen, Ph.D, professor, cellular and integrative physiology, Indiana University, Indianapolis; June 30, 2008, Hypertension, online