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Wrong Graeme Semple?

Graeme Semple

Vice President Discovery Chemistry

Arena Pharmaceuticals , Inc.

HQ Phone:  (858) 453-7200

Direct Phone: (858) ***-**** ext. ****direct phone

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I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Community Edition at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

Arena Pharmaceuticals , Inc.

6154 Nancy Ridge Drive

San Diego, California,92121

United States

Company Description

Arena embraces the challenge of improving health by seeking to bring innovative medicines targeting G protein-coupled receptors to patients. Arena's focus is discovering, developing and commercializing drugs to address unmet medical needs, and BELVIQ® (lorcas...more

Background Information

Employment History

Chemist

AstraZeneca PLC


Head of Chemistry

Ferring Research Institute Inc


Co-founder and Vice President Chemistry

Beacon Discovery Inc


Post Doc

University of Oxford


Affiliations

University of Bath

Post-Doctoral Fellow


Education

Ph.D.


Ph.D.

Chemistry

University of Warwick , UK


Web References(26 Total References)


Beacon Team - Beacon Discovery

www.beacondiscovery.com [cached]

Graeme Semple, Ph.D.
Vice President, Chemistry Graeme Semple has more than 26 years of drug discovery experience in the pharmaceutical industry, both in biotech and big pharma, most recently at Arena Pharmaceuticals where he was VP of Discovery Chemistry and oversaw medicinal chemistry and early development projects. More than a dozen of these projects delivered candidates into preclinical and clinical development in the areas of Metabolism, CNS, Inflammation and Cardiovascular disease. Prior to Arena, he was a Disease Area Chemist at AstraZeneca, Mölndal, Sweden, where he initiated a number of early stage medicinal chemistry projects in the GI area. Prior to AstraZeneca, he was Head of Chemistry at Ferring Research Institute, Southampton, U.K., where he led chemistry groups contributing to multi-national collaborative projects that delivered clinical candidates in the areas of cardiovascular, GI and urology. He is a co-inventor of the GnRH antagonist drug Firmagon ® (Degarelix) which has been approved in 74 countries. He was a post-doctoral fellow at the Universities of Bath and Oxford, UK and has a Ph.D. in Chemistry from the University of Warwick, UK.


Beacon Team – Beacon Discovery

www.beacondiscovery.com [cached]

Graeme Semple, Ph.D.
Vice President, Chemistry Graeme Semple has more than 26 years of drug discovery experience in the pharmaceutical industry, both in biotech and big pharma, most recently at Arena Pharmaceuticals where he was VP of Discovery Chemistry and oversaw medicinal chemistry and early development projects. More than a dozen of these projects delivered candidates into preclinical and clinical development in the areas of Metabolism, CNS, Inflammation and Cardiovascular disease. Prior to Arena, he was a Disease Area Chemist at AstraZeneca, Mölndal, Sweden, where he initiated a number of early stage medicinal chemistry projects in the GI area. Prior to AstraZeneca, he was Head of Chemistry at Ferring Research Institute, Southampton, U.K., where he led chemistry groups contributing to multi-national collaborative projects that delivered clinical candidates in the areas of cardiovascular, GI and urology. He is a co-inventor of the GnRH antagonist drug Firmagon ® (Degarelix) which has been approved in 74 countries. He was a post-doctoral fellow at the Universities of Bath and Oxford, UK and has a Ph.D. in Chemistry from the University of Warwick, UK.


maggichurchouseevents.co.uk

Graeme Semple, Arena Pharmaceuticals, USA


GPCR-Based Drug Discovery - Discovery On Target - Day 1

www.discoveryontarget.com [cached]

Graeme Semple, Ph.D., Vice President, Discovery Chemistry, Arena Pharmaceuticals


GPCR-Based Drug Discovery Conference - Day 1 - Discovery On Target

www.discoveryontarget.com [cached]

Graeme Semple, Ph.D., Vice President, Discovery Chemistry, Arena Pharmaceuticals, Inc.
The design and optimization of new prostacyclin receptor agonists with oral activity in rat models of pulmonary arterial hypertension will be described. As well as in vitro and in vivo potency, special attention was paid to pharmacokinetic parameters eventually resulting in the discovery of the clinical candidate, APD811.


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