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6118 Nancy Ridge Dr.
San Diego, California 92121
Beacon Discovery was founded in 2016 to take advantage of unique advances in the science of G-Protein Coupled Receptors (GPCRs). We are comprised of a team of dedicated scientists who have worked together for the last decade. Our mission is to efficiently ... more
Vice President Discovery Chemistry
Head of Chemistry
University of Bath
University of Warwick , UK
GPCR-Based Drug Discovery - Discovery On Target - Day 1
GPCR-Based Drug Discovery Conference - Day 1 - Discovery On Target
The design and optimization of new prostacyclin receptor agonists with oral activity in rat models of pulmonary arterial hypertension will be described.
As well as in vitro and in vivo potency, special attention was paid to pharmacokinetic parameters eventually resulting in the discovery of the clinical candidate, APD811.
Grand View Media Group
Gilbert + Tobin