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2011-04-24T00:00:00.000Z

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Wrong Gosia Korbas?

Dr. Gosia Korbas

Staff Scientist

BioXAS

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BioXAS

Background Information

Affiliations

Member of the Molecular and Environmental Sciences Research Group In the Department of Geological Sciences
University of Saskatchewan

Web References (34 Total References)


Dr. Gosia Korbas, ...

pcvi.com [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.

"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


Dr. Gosia Korbas, ...

www.speciation.net [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.


Dr. Gosia Korbas, ...

absolutelyoptical.com [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.

"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


Dr. Gosia Korbas, ...

absolutelyoptical.com [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.

"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


Canadian Light Source Staff ...

www.rdmag.com [cached]

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head. Image: Mark Ferguson

...
Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.
"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70% of protein-coding human genes have their counterparts in zebrafish, and 84% of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.

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