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Gosia Korbas

Staff Scientist

Canadian Light Source Inc

HQ Phone:  (306) 657-3500

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I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Community Edition at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

Canadian Light Source Inc

44 Innovation Boulevard

Saskatoon, Saskatchewan,S7N 2V3

Canada

Company Description

Canadian Light Source Inc. (CLSI) operates the Canadian Light Source, Canada's national synchrotron research facility. Located at the University of Saskatchewan in Saskatoon, the CLS is a world-class, state-of-the-art facility that is advancing Canadian scienc...more

Background Information

Employment History

Staff Scientist

BioXAS


Affiliations

University of Saskatchewan

Member of the Molecular and Environmental Sciences Research Group In the Department of Geological Sciences


Web References(8 Total References)


www.lightsource.ca

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a
Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head. Using powerful synchrotron X-rays, CLS Staff Scientist Dr. Gosia Korbas and a team of researchers from the University of Saskatchewan have revealed how organic mercury can interfere with vision by targeting the outer segments of photoreceptor cells in zebrafish. "There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas.


www.rdmag.com

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head. Image: Mark Ferguson
Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside. "There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina." Korbas and the team of researchers from the University of Saskatchewan including Profs. Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70% of protein-coding human genes have their counterparts in zebrafish, and 84% of genes linked to human diseases can be found in zebrafish. "Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


www.lightsource.ca [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.
"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina." Korbas and the team of researchers from the University of Saskatchewan including Profs. Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish. "Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded. Acknowledgments: This work was supported by the Canadian Institutes of Health Research, the Saskatchewan Health Research Foundation and the Natural Sciences and Engineering Research Council of Canada. Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head. Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head.


www.lightsource.ca [cached]

Gosia Korbas, BioXAS Staff Scientist
Gosia comes to the CLS from the University of Saskatchewan where she was a member of the Molecular and Environmental Sciences Research Group in the Department of Geological Sciences.


pcvi.com [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.
"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina." Korbas and the team of researchers from the University of Saskatchewan including Profs. Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish. "Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


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