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2013-09-12T00:00:00.000Z

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Dr. Gosia Korbas

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Canadian Light Source Inc

44 Innovation Blvd.

Saskatoon, Saskatchewan S7N 2V3

Canada

Company Description

The CLS is one of the country's largest science projects of the last 30 years. Due to open for business this fall, the U of S-owned national research facility will be used by researchers in industry, government and academia. Synchrotron light - millions o ... more

Find other employees at this company (219)

Background Information

Employment History

Staff Scientist

BioXAS

Affiliations

Member of the Molecular and Environmental Sciences Research Group In the Department of Geological Sciences
University of Saskatchewan

Web References (33 Total References)


Canadian Light Source Staff Scientist ...

www.lightsource.ca [cached]

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head.
...
Using powerful synchrotron X-rays, CLS Staff Scientist Dr. Gosia Korbas and a team of researchers from the University of Saskatchewan have revealed how organic mercury can interfere with vision by targeting the outer segments of photoreceptor cells in zebrafish.
"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas.


Canadian Light Source Staff ...

www.rdmag.com [cached]

Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head. Image: Mark Ferguson

...
Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.
"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70% of protein-coding human genes have their counterparts in zebrafish, and 84% of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.


Canadian Light Source Inc.

www.lightsource.ca [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.

"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.
Acknowledgments: This work was supported by the Canadian Institutes of Health Research, the Saskatchewan Health Research Foundation and the Natural Sciences and Engineering Research Council of Canada.
Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head.
Canadian Light Source Staff Scientist Gosia Korbas displays a cross section of a zebrafish head.


Dr. Gosia Korbas, ...

www.speciation.net [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.


Eye Health Headlines

pcvi.com [cached]

Dr. Gosia Korbas, BioXAS staff scientist at the Canadian Light Source (CLS), says the results of this experiment show quite clearly that methylmercury localizes in the part of the photoreceptor cell called the outer segment, where the visual pigments that absorb light reside.

"There are many reports of people affected by methylmercury claiming a constricted field of vision or abnormal colour vision," said Korbas. "Now we know that one of the reasons for their symptoms may be that methylmercury directly targets photoreceptors in the retina."
Korbas and the team of researchers from the University of Saskatchewan including Profs.
...
Korbas said zebrafish are an excellent model for investigating the mechanisms of heavy metal toxicity in developing vertebrates. One of the reasons for that is their high degree of correlation with mammals. Recent studies have demonstrated that about 70 per cent of protein-coding human genes have their counterparts in zebrafish, and 84 per cent of genes linked to human diseases can be found in zebrafish.
"Researchers are studying the potential effects of low level chronic exposure to methylmercury, which is of global concern due to methylmercury presence in fish, but the message that I want to get across is that such exposures may negatively affect vision. Our study clearly shows that we need more research into the direct effects of methylmercury on the eye," Korbas concluded.

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