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Wrong Gordon Vehar?

Dr. Gordon A. Vehar

Vice President of Research

BioMarin Pharmaceutical Inc.

Direct Phone: (415) ***-****       

Email: g***@***.com

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BioMarin Pharmaceutical Inc.

105 Digital Drive

Novato, California 94949

United States

Company Description

BioMarin develops and commercializes innovative biopharmaceuticals for serious diseases and medical conditions. The company's product portfolio comprises five approved products and multiple clinical and pre-clinical product candidates. Approved products i ... more

Find other employees at this company (2,496)

Background Information

Employment History

Student Vision

Staff Scientist

Genentech , Inc.

Vice President of Research and Development

Raven Biotechnologies , Inc.


Scientific Advisory Board Member
Actokine Therapeutics

Member, Scientific Advisory Board
Oklahoma Center for Molecular Medicine


Ph. D.

University of Cincinnati Medical School

Web References (56 Total References)

BioMarin : About Us : Leadership Team : Management Team [cached]

Gordon Vehar, Ph. D. Vice President, Research

Gordon Vehar

The population for early onset ... [cached]

The population for early onset Alzheimer's is "relatively tiny," according to Dr. Gordon Vehar, vice president of research for BioMarin. A 2007 report by the Alzheimer's Association put the number at around 200,000.

"As devastating as Familial Alzheimer's ... [cached]

"As devastating as Familial Alzheimer's is, there are no therapies being researched for it because the patient population is relatively tiny," said Dr. Gordon Vehar, vice president of research for BioMarin.

A report issued by the Alzheimer's Association in March 2007 puts the number of people with AD who are younger than 65 at around 200,000 in the U.S.
"Ironically, most all the research on Alzheimer's is being done with mice that have been bred to develop the Familial type, even though the target is the much larger Alzheimer's population," said Dr. Vehar.
According to Dr. Vehar, if the early research should successfully lead to a therapy, BioMarin would take it through the FDA approval process and market it.
Tags BioMarin Pharmaceutical, Buck Institute, Dale Bredesen, Familial Alzheimer's, Gordon Vehar, Marin County, Novato | Category Featured Box, Industry News, Position, Technology

It would likely take four to ... [cached]

It would likely take four to eight years of research on mice and monkeys before the research ever reached a human trial, said Gordon Vehar, BioMarin's vice president of research. Such a trial could cost tens or hundreds of millions of dollars, he said.

"Drug development is a very high-risk area," Vehar said.
has an above-average record for moving its drugs into clinical trials, with 25 to 30 percent of its animal-tested drugs receiving approvals for humans, Vehar said. But industry-wide, fewer than 10 percent of drugs targeting the central nervous system - Alzheimer's falls into that category - advance from clinical trials to the marketplace, Vehar said.
The new research will focus specifically on a rare type of inherited, early onset Alzheimer's that affects patients as young as 30. The early onset form of the disease affects only about 34,000 patients.
Focusing on a rare disorder follows BioMarin's typical approach to drug research, Vehar said. The company looks for disorders that affect relatively small populations and are linked to specific genes, he said.
"By having such focused patient selection, we can quickly evaluate whether the drugs work or not," Vehar said.
If the research is successful, it could eventually lead to treatments for the broader Alzheimer's population, Vehar said.

Gordon Vehar, Ph.D. - BioMarin Executive Team - Management [cached]

Gordon Vehar, Ph. D.

Gordon Vehar, Ph.D.
Dr. Gordon Vehar is the former Vice President of Research and Development for Raven Biotechnologies. He is the inventor of numerous biotechnology patents and the recipient of a collection of prestigious scientific awards including two Distinguished Inventor of the Year Awards from Intellectual Property Owners, Inc.
Dr. Vehar also served in various roles throughout a 20-year tenure with Genentech, including Director of Cardiovascular Research and Staff Scientist for Cardiovascular Research and Protein Chemistry. Also at Genentech, he served as Project Team Leader on various drug discovery and development projects, which yielded four marketed products. He is the recipient of the Murray Thelin Award for Outstanding Research presented by the National Hemophilia Foundation, the Inventor of the Year Award given by Intellectual Property Owners, Inc., for the human tissue plasminogen activator (t-PA) patent for the treatment of heart attacks and stroke, and the Distinguished Inventor of the Year Award from Intellectual Property Owners, Inc. for the patent on recombinant Factor VIII, a genetically engineered clotting factor enabling production of a therapeutic product for treating hemophilia A. Dr. Vehar has served on the Scientific Advisory Board for the Oklahoma Center for Molecular Medicine, he is an inventor with 37 issued patents and is the author of more than 35 publications. Dr. Vehar received a Ph.D. from the University of Cincinnati Medical School.

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