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Wrong George Dubyak?

Dr. George R. Dubyak

HQ Phone: (216) 368-2000

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Case Western Reserve University

Bolwell Building Room B140 11100 Euclid Avenue

Cleveland, Ohio 44106

United States

Company Description

Case Western Reserve University is one of the country's leading private research institutions. Located in Cleveland, we offer a unique combination of forward-thinking educational opportunities in an inspiring cultural setting. Our leading-edge faculty eng ... more

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Web References (27 Total References)

George Dubyak, Case ... [cached]

George Dubyak, Case Western Reserve Univ. School of Medicine

George R. Dubyak, Case ... [cached]

George R. Dubyak, Case Western Reserve University, Cleveland, OH

Their findings help explain the mystery ... [cached]

Their findings help explain the mystery of how relatively localized contact between a cell and a pathogen or product of cell damage can lead to widespread inflammation, explained George Dubyak, a cell physiologist at Case Western Reserve University in Cleveland, Ohio, who was not involved in the study. "The inflammasome specks can become carriers for intracellular signaling," he said.

Dubyak suggested that another route would be to block pyroptosis of cells with activated inflammasomes to prevent ASC specks from escaping in the first place. He added that an important next step will be understand how healthy tissues put the brakes on inflammasome-induced inflammation.
"A lot of the inflammasome biology that was not making sense to us is starting to make a lot more sense," he said.

Department of Pathobiology [cached]

George R. Dubyak, PhD, Professor of Physiology and Biophysics, Case Western Reserve University

Department of Pathobiology [cached]

George R. Dubyak, PhD, Professor of Physiology and Biophysics, Case Western Reserve University

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