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This profile was last updated on 11/30/13  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. C. Frank Starmer

Wrong Dr. C. Frank Starmer?

Associate Dean , Learning Technol...

Email: f***@***.sg
Duke-NUS Graduate

Employment History

  • Associate Provost for Information Technology
    Medical University of South Carolina
  • Associate Dean for Learning Technologies and Professor of Biostatistics and Bioinformatics
    Duke University
  • Professor of Computer Science and Experimental Medicine (Cardiology)
    Duke University
  • Professor and Associate Dean for Learning Technologies
    Duke-NUS Graduate Medical School Singapore
  • Professor and Associate Dean for Learning Technologies
    Duke-NUS Graduate Medical School
  • Visiting Professor
    Institute of Theoretical and Experimental Biophysics
  • Visiting Professor
    Institute of Theoretical and Expermental Biophysics, Pushchino Russia

Board Memberships and Affiliations


  • Ph.D.
66 Total References
Web References
"Building the Arthur Ravenel Bridge: A ..., 14 Oct 2007 [cached]
"Building the Arthur Ravenel Bridge: A Photographic Essay" will feature 30 photographs by Dr. C. Frank Starmer, who documented the entire construction process of the Arthur Ravenel Bridge and the demolition of the two older bridges that spanned Charleston Harbor between Mount Pleasant and Charleston.
"I got to know Frank when he was on the faculty at MUSC and he started a Web site on the demolition of the old bridges (the Grace Memorial and Pearman) and traced the entire process for two years," says Greenberg.
Starmer is associate dean for learning technologies and professor of biostatistics and bioinformatics at Duke University and also at the Duke-National University of Singapore Graduate Medical School.As he now lives in Singapore, Starmer will not be present for the opening.
Computer Science - Duke University, 28 Mar 2010 [cached]
Frank Starmer Duke CS Image Professor Emeritus of Computer Science
Vulnerability of cardiac dynamics - Scholarpedia, 30 Oct 2014 [cached]
C. Frank Starmer (2007), Scholarpedia, 2(11):1847.
Frank Starmer
Dr. C. Frank Starmer, Duke - NUS Graduate Medical School Singapore
Figure 1: Each propagating excitation wave is trailed by a region of recovering cells.
For example, use-dependent drugs that bind to cardiac sodium channels reduce the density of sodium channels and retard the recovery of excitability (Starmer, C.F., Lastra, A.A., Nesterenko, V.V. and Grant, A.O. 1991; Starmer, C.F., Lancaster, A.R., Lastra, A.A. and Grant. A.O., 1992)resulting in slowed conduction. Similarly sodium channel mutations that alter cardiac excitability have an enhanced proarrhythmic potential (Grant, A.O., et. al, 2002; Starmer, C.F., Colatsky, T.J. and Grant, A.O., 2003a). Clinical trials of antiarrhythmic drugs have uniformly revealed that use-dependent drugs that reduce excitability by binding to cardiac sodium channels display proarrhythmic behavior, i.e. there is an increase in the rate of sudden cardiac death associated with the use of drugs classified as antiarrhythmic (see Cardiac Arrhythmia Suppression Trial (CAST) Investigators, 1989; The Cardiac Arrhythmia Suppression Trial-II Investigators, 1992). The mechanism of failure of these clinical trials is consistent with the concept of the vulnerable region described above. Specifically any drug that reduces the excitability will also slow propagation of a wave thereby enlarging the vulnerable region and the probability that spontaneous oscillation of cells within the vulnerable region will trigger a reentrant arrhythmia (Wiener, N. and Rosenblueth, A, 1946; Starmer et. al, 1991, Starmer et. al, 1993, Starobin, J., Zilberter, Y.I. and Starmer, C.F., 1994).
Whitcomb, D.C., Gilliam, F.R., Starmer, C.F. and Grant, A.O. Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine. Journal of Clinical Investigation 1989; 84:1629-1636. Starmer, C.F., Lastra, A.A., Nesterenko, V.V. and Grant, A.O. A proarrhythmic response to sodium channel blockade: Theoretical model and numerical experiments. Circulation 1991; 84:1364-1377. Starmer, C.F., Lancaster, A.R., Lastra, A.A. and Grant. A.O. Cardiac instability amplified by use-dependent Na channel blockade. American Journal of Physiology 1992; 262:H1305-H1310. Nesterenko, V.V., Lastra, A.A., Rosenshtraukh, L.V. and Starmer, C.F.
Gomez-Gesteira, M., Fernandez-Garcia, G., Munuzuri, A.P., Perez-Munuzuri, V., Krinsky, V.I., Starmer, C.F. and Perez-Villar, V. Vulnerability in an excitable Belousov-Zhabotinsky medium: from 1D to 2D. Physica D 1994; 76:359-368. Starobin, J., Zilberter, Y.I. and Starmer, C.F. Vulnerability in one-dimensional excitable media. Physica D. 1994; 70:321-341.
Starmer, C.F.,Romashko, D.,Reddy, R.S., Zilberter, Y.I., Starobin, J., Grant, A.O. and Krinsky, V.I. Proarrhythmic Response to Potassium Channel Blockade: Numerical Studies of Polymorphic Tachyarrhythmias. Circulation 1995; 92:595-605.
Grant, A.O., Carboni, M.P., Neplioueva, V., Starmer, C.F., Memmi, M., Napolitano, C. and Priori, S. Long QT, Brugada and conduction system disease linked to a single Na channel mutation. J. Clin Invest. 2002; 110:1201-1209. Starmer, C.F., Colatsky, T.J. and Grant, A.O. What happens when cardiac Na channels lose their function? 1: Numerical studies of the vulnerable period in tissue expressing mutant channels. Cardiovascular Research 2003a; 57:82-91. Starmer, C.F., Grant, A.O. and Colatsky, T.J.
C. Frank Starmer (2007) Initiation of excitation waves. Scholarpedia, 2(2):1848.
"Vulnerability of cardiac dynamics" by C. Frank Starmer is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License . Permissions beyond the scope of this license are described in the Terms of Use
Watch the Port of Charleston in action and Charleston's new Cooper River Bridge (Arthur Ravenel Bridge) Grow [cached]
Frank Starmer, Medical University of South Carolina.
What I am trying to say is that this web site is a community project - not just Frank Starmer taking photos for his grandkids.
Watch the unbuilding (demolition) of the Pearman and Grace Bridges (old Cooper River Bridges), 1 Jan 2005 [cached]
Frank Starmer, Medical University of South Carolina.
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