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2016-08-08T00:00:00.000Z

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Wrong Ehud Isacoff?

Dr. Ehud Isacoff Y.

Chair and Professor of Neurobiology

Berkeley

HQ Phone: (510) 845-7793

Email: e***@***.edu

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Berkeley

2736 Bancroft Way

Berkeley, California 94704

United States

Company Description

The Berkeley Historical Society, founded in the summer of 1978 from the ad-hoc Berkeley Centennial Celebration Committee, is a non-profit, all volunteer group dedicated to researching, preserving and sharing Berkeley's history. Through exhibits, lectures, ... more

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Background Information

Employment History

Director

Helen Wills Neuroscience Institute

TREK1 Specialist

National

Professor of Neurobiology and Chair

The Graduate Group

Affiliations

Postdoctoral Fellow
University of California , San Francisco

Education

B.S.

Biology

McGill University

Ph.D.

Neurophysiology

McGill University

Web References (72 Total References)


Biological Imaging | QB3

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Ehud Isacoff


Faculty | QB3

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Ehud Isacoff


Faculty | QB3

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Ehud Isacoff


Board of Scientific Governors | LMRI

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Profile for:Ehud Isacoff, Ph.D.

...
Ehud Isacoff, Ph.D.
Dr. Isacoff works on the mechanisms of ion channel function and the molecular basis of synaptic transmission and plasticity, as well as on the development of neural circuits. His work has elucidated the basis of voltage sensing and gating of voltage-gated channels and enzymes. He has developed novel methods in biological optics:
a) Voltage Clamp Fluorometry, real-time monitoring of structural rearrangements underlying gating at the ensemble and single molecule levels; b) FlaSh, the first genetically-encoded optical sensor of voltage; c) SynapCams, postsynaptically targeted Ca2+-sensing fluorescent proteins for imaging synaptic transmission at quantal resolution; d) Single molecule subunit counting to determine subunit stoichiometry of functional membrane protein complexes in live cells; and e) Light-gates, opto-chemical toggles that agonize, antagonize or block channels and receptors rapidly and reversiblya novel branch of optogenetics that uniquely controls native vertebrate synaptic signaling proteins, including receptors implicated in diverse forms of synaptic plasticity. He has adapted these to control signaling in neurons and gliotransmission in astrocytes. His optogenetic studies on zebrafish have provided insight into visually-guided behavior, and the development and function of the locomotor system.


The researchers, collaborating with Prof. ...

www.aftau.org [cached]

The researchers, collaborating with Prof. Joel Hirsch of TAU's Faculty of Life Sciences, Prof. Dominic Walsh of Harvard University, and Prof. Ehud Isacoff of University of California Berkeley, harnessed a combination of cutting-edge high-resolution optical imaging, biophysical methods and molecular biology to examine APP-dependent signalling in neural cultures, brain slices, and mouse models.

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