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University of Florida
2015 North Jefferson Street
The University of Florida is one of the nation's largest public universities. A member of the Association of American Universities, UF receives more than $550 million annually in sponsored research funding. Through its research and other activities, UF co
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Global Infection Control - References
Professor Dov Borovsky
University of Florida
WNDU.com: Mosquito 'diet pill' has potential to save lives
Dr. Dov Borovsky, a University of Florida insect biochemist, "If they cannot break it down to small components they need for development, they become stagnant, they cannot grow, they actually starve because they can't get the nutrients they need and they die."
Potential to save livesResearchers say with the threat of the West Nile virus and other mosquito borne illnesses, the mosquito diet pill has the potential to save lives.Consumer product testing started this month and pending EPA approval, the granules could be available to consumers within a year.The product has been licensed to a North Carolina company, which plans to market the non-toxic, environmentally safe granules to consumers.
"They can be sold for people that can actually treat their ponds, yards, water bath that a lot of time accumulates a lot of mosquito larvae or even standing water in the yard, you can put these granules in," said Borovsky
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Insect Biotechnology - IBI Company Profile
Insect Biotechnology, Inc. was founded in California in 1993 by Dr. John Bennett and Dr. Alan Brandt to license a patented technology of the University of Florida for a unique new platform bioinsecticide technology discovered by Dr. Dov Borovsky at the Florida Medical Entomology Laboratory in Vero Beach.
has identified and characterized the peptide hormones that down-regulates expression of trypsin-like serine proteases which are primary insect digestive proteases.
has shown there is a TMOF binding site on the hemolymph (insect bloodstream) side of the gut and has identified the TMOF Receptor which binds to it.
...Dr. Dov Borovsky, Co-founder and R&D consultant to IBI, is Professor of Medical Entomology at the University of Florida Medical Entomology Laboratory in Vero Beach, FL.He
is responsible for the primary scientific discoveries upon which the Company is based and continues to actively expand the scientific and technological base of the Company with over 100 scientific publications.Dr. Borovsky received a NIH Career Development Award and is an Adjunct Professor of Biochemistry and Molecular Biology in the University of Miami Department of Biochemistry and Molecular Biology.Dr. Borovsky is also the Lady Davis Visiting Professor in the Department of Parasitology at Hebrew University in Jerusalem and recipient of a Visiting Professorship to Catholic University of Leuven, Belgium.He also serves on the editorial boards of the Journal of Medical Entomology (past Chairman) and the Archives of Insect Biochemistry and Physiology.Dr. Borovsky has a Ph.D. in Biochemistry from the University of Miami.Dr. Borovsky
received the Silver Plow Award from the U.S. Department of Agriculture
in 1999.Professor Borovsky (center) received the 1999 USDA Silver Plow Award from USDA Secretary Dan Glickman (right) and USDA Under Secretary Robert Rominger (left).
Scientists genetically modified tobacco ...
Scientists genetically modified tobacco mosaic virus so that it produces a natural, environmentally friendly insecticide, turning the pathogen into a microscopic chemical factory, said Dov Borovsky, an entomologist with UF's Institute of Food and Agricultural Sciences.The modified virus is almost completely harmless to plants and simply produces the insecticide.Plants inoculated with the virus quickly accumulate enough of the insecticide to kill insect pests that consume their leaves, said Borovsky, who works at the Florida Medical Entomology Laboratory in Vero Beach and is affiliated with UF's Genetics Institute.
"This is the first time we know of that anybody put on tobacco mosaic virus something that actually can act as an insecticide and protect the plant," said Borovsky
, lead author of the paper.Tobacco mosaic virus is commonly used in genetic research because genes can be added to it easily.
The chemical, known as trypsin -modulating oostatic factor, or TMOF, stops insects from producing a crucial digestive enzyme called trypsin, he
holds 14 patents on TMOF technologies, some of which have been licensed to private companies, Borovsky
said.He discovered TMOF, a hormone produced by female mosquitoes' ovaries, years ago and has researched the chemical ever since.
Scientists plan to investigate further practical applications of TMOF, he
"TMOF works against the diaprepes citrus root weevil, it causes a lot of problems here in Florida," Borovsky
UF researchers have produced genetically modified alfalfa plant that generates TMOF, he
University of Florida insect ...
University of Florida insect biochemistry professor Dov Borovsky agrees that if more money isn't given to research, the future of mosquito control is doomed.He
finds in the history of the school adequate support for the kinds of changes he's
going to make.