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This profile was last updated on 10/30/15  and contains information from public web pages and contributions from the ZoomInfo community.

Denise C. Connolly

Wrong Denise C. Connolly?

Director Biosample Repository Fac...

Phone: (215) ***-****  
Email: d***@***.org
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia , Pennsylvania 19111
United States

Company Description: Fox Chase Cancer Center, part of the Temple University Health System, is one of the leading cancer research and treatment centers in the United States. Founded in...   more

Employment History

24 Total References
Web References
That's what really causes mortality," ..., 8 April 2014 [cached]
That's what really causes mortality," says Denise C. Connolly, PhD, Associate Professor at Fox Chase and senior researcher for the project.
Liz Tilberis Early Career Award - OCRF Grantees | Ovarian Cancer Research Fund, 24 April 2014 [cached]
2006 & 2003 Liz Tilberis Grant Recipient - Denise C. Connolly
Denise C. Connolly, Ph.D. - Fox Chase Cancer Center (Renewal)
Denise C. Connolly, Ph.D. - Fox Chase Cancer Center
Research done by Fang Xiao, MD, ..., 7 April 2014 [cached]
Research done by Fang Xiao, MD, PhD, Research Associate at Fox Chase, and Denise Connolly, PhD, Associate Professor at Fox Chase, led them to identify the importance of FAK in ovarian cancer, but the enzyme wasn't part of their investigation at the beginning.
But STAT3 itself is not a promising candidate for targeted therapy, Connolly says, because, as a transcription factor, it lacks catalytic activity that could be blocked directly.
Suspecting they could find a related molecule to inhibit the protein's actions in cancer cell lines, Xiao and Connolly conducted laboratory experiments to better understand the underlying biology.
"What's unique about Xiao's study is that focal adhesion kinase so far hasn't been shown to activate STAT3 in solid tumors," says Connolly, whose research focuses on understanding the biological underpinnings of epithelial ovarian cancer.
Fox Chase Cancer Center : Denise C. Connolly, PhD - People, 5 Mar 2011 [cached]
Denise C Connolly, PhD
Denise C Connolly, PhD Assistant Professor Office Phone: 215-728-1004 Fax: 215-728-2741
Denise C Connolly, PhD, Principal Investigator
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