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2017-02-06T00:00:00.000Z

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Dr. David A. Low

Professor In Department of Molecular, Cellular, and Developmental Biology

University of California , Santa Barbara

HQ Phone: (805) 893-8000

Email: l***@***.edu

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University of California , Santa Barbara

342 Lagoon Road Mail Code 2055

Santa Barbara, California 923106-2055

United States

Company Description

The University of California, Santa Barbara (UCSB) is one of 10 universities in the University of California system, and is one of only 62 research-intensive institutions elected to membership in the prestigious Association of American Universities. The d ... more

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Background Information

Employment History

Professor In Department of Molecular, Cellular, and Developmental Biology

UC Santa Barbara Foundation

Professor

MCDB

Professor

University of Utah

Affiliations

Fellow
American Association for the Advancement of Science

Fellow
American Academy of Microbiology

Postdoctoral Fellow
Stanford University

Education

Ph.D.

University of California , Irvine

Ph.D.

University of California at Irvine

Ph.D.

cellular biochemistry

UC Irvine

bachelor's degree

biology

UC San Diego

master's degree

microbiology

San Diego State University

Web References (55 Total References)


Remedyne Management Team

www.remedyne.com [cached]

David Low, Ph.D.Chief Scientific Officer and Director

Dr. Low is currently a professor in the department of Molecular, Cellular and Developmental Biology at the University of California, Santa Barbara.Previously, he served as a professor in the department of Pathology at the University of Utah and also served on editorial boards of Applied and Environmental Biology and Microbiology.Dr. Low has been honored with an NIH Career Development Award and the LaSalle Memorial Scholarship in Microbiology.He has contributed to over 53 publications in biochemistry, immunology and molecular biology and is a co-holder of the patent (pending) for Remedyne's DNA Adenine Methylase Technology.Dr. Low completed his Ph.D. at the University of California, Irvine and received his postdoctoral fellow at Stanford University.


Kenny Slaught - Congratulates UCSB for Receiving Grand Challenges Explorations Grant

www.accesswire.com [cached]

David Low, a professor in UCSB's Department of Molecular, Cellular, and Developmental Biology, will pursue an innovative global health and development research project titled, "Strategy for development of enteric pathogen-specific phage. Low's research focuses on a new way to deal with serious bacterial pathogens that are becoming resistant to many once-powerful antibiotics.


Self-Perpetuating Structural States in Biology, Disease, and Genetics

www.nasonline.org [cached]

David Low, UC Santa Barbara


Gordon Research Conferences - 2014 Program - Bacterial Cell Surfaces

www.gordonresearchconferences.org [cached]

David Low (University of California, Santa Barbara) "Mechanisms of Self/Non-Self Recognition and Generation of Toxin Diversity in CDI and Rhs Contact-Dependent Growth Inhibition Systems"


One bacterial cell can stop the growth of another on physical contact

www.rxpgnews.com [cached]

"This has potential implications for new antibiotics," said Low.

...
The discovery by a team of scientists working in the laboratory of David Low, professor of biology at the University of California, Santa Barbara, is reported in the August 19 issue of the journal Science. The findings indicate that Escherichia coli, one culprit in urinary tract infections, contains genes that when turned on block the growth of other E. coli bacteria that they touch. The finding was a complete surprise to the scientists, said Low.
The discovery may eventually lead to new antimicrobial agents to halt bacterial growth which would be an entirely new system to shut bacteria down, according to the scientists. "This has potential implications for new antibiotics," said Low.
...
"We don't know if these 'stopped' cells are dead or alive," said Low.
...
Low said that one possible interpretation is that bacteria use this system to eliminate competition in the environments they grow in. "Another possibility is that the bacteria use the CDI system to shut themselves off inside a host, going into a dormant state where they may go undetected by the immune system," he said.
Thousands of women in this country have chronic urinary tract infections, noted the scientists. The disease seems to go away for awhile, then something triggers recurrence of the disease.
Work by Scott Hultrgen at Washington University has indicated that E. coli cells may hide in the walls of the bladder and urinary tract in a dormant state, explained Low.
...
"This research is in its infancy, but opens the door for exploration of the roles of contact-dependent growth inhibition in urinary tract infections and possibly other diseases," said Low.
"Aoki has discovered an entirely new phenomenon," explained Low, who has studied E. coli for over 20 years.
...
David Low can be reached at (805) 893-5597, or by e-mail at [email protected]

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