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Lecturer In Stratified Medicine, BSc Hons Course Director
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Derry, County Londonderry,BT52 1SA
Ulster University has for over 40 years enjoyed a close relationship with policing in Northern Ireland. The University has provided a range of academic courses, which have been designed to meet the changing educational needs of police officers and support staf... more.
Biochip Research Scientist
FX Reconciliations - Senior Bank Official
Director and Secretary
56th FIM Motorcycle Rally, Killarney, Ireland
Enterprise Educators UK
Queen's University Belfast
Senior Research Fellow
School of Management and Economics at Queen
Senior Teaching Fellow In Entrepreneurship
University Management School
Senior Teaching Fellow
Centre for Cancer Research and Cell Biology
After his Biochemistry degree, Dr David Gibson worked at Randox Laboratories Ltd, where he was responsible for designing and commercializing novel biochip array diagnostic tests.
He was awarded a Ph.D. in 2001 from the Centre for Cancer Research and Cell Biology, Queen's University Belfast, for research which exposed the role of cysteine proteinases in brain tumour invasion. During a Wellcome Trust Fellowship Dr Gibson investigated the role of inflammation in a hypoxia driven model of diabetic retinopathy at the Centre of Vision and Vascular Science, QUB. Since 2003 Dr Gibson focused his research efforts on the discovery and validation of protein biomarkers which could improve the management of arthritis patients. During his time at the Rooney laboratory in the Centre of Infection and Immunity, QUB he spearheaded the use of proteomic and bioinformatic strategies to identify a plasma and synovial fluid protein 'fingerprint' that predicts disease spread in children with arthritis. He also identified post translational modifications in the Vitamin D binding protein that may act as a modulator of inflammation in juvenile arthritis patients. In 2009, Dr Gibson was awarded a prestigious travel fellowship from Arthritis Research UK to conduct research at the Duncan laboratory at the University of Colorado, Denver over two years. From this fellowship Dr Gibson brings expertise in mass spectrometry analyses of clinically relevant proteins, peptides and post-translational modifications to his current post at the University of Ulster. Research Interests Stratified Medicine- 'the right treatment, for the right person, at the right time' In 2013 Dr Gibson took up his post as Lecturer in Stratified Medicine and his research is focused on adult rheumatoid arthritis (RA). He is particularly interested in the development of new prognostic and predictive tools to improve the clinical management of arthritis patients. David's current research within the Northern Ireland Centre for Stratified Medicine is based at C-TRIC within the Altnagelvin Hospital campus, Londonderry. He employs novel mass spectrometry based methods to robustly identify and quantify disease associated proteins. These methods are useful to investigate the role of protein modification in arthritis, as a surrogate measure of inflammatory activity. He is also interested in the application of protein array technologies for autoantibody screening. He will initially establish research programmes in three key areas: 1. How RA patients develop resistance to biologic therapies. 2. How inflammation and joint destruction can persist without clinical symptoms. 3. Can alternate methods of blood sampling support patient care away from the hospital clinic. Ultimately, Dr Gibson will develop novel monitoring tools to help clinicians target those patients who do not respond well to current therapeutics or develop drug resistance over time. Dr David Gibson Lecturer in Stratified Medicine Biomedical Sciences Research Institute Butt, Aisha Q, McArdle, Angela, Gibson, David, Fitzgerald, Oliver and Pennington, Stephen R (2015) Psoriatic arthritis under a proteomic spotlight: application of novel technologies to advance diagnosis and management. Current Rheumatology Reports, 17 (5). pp. 509. Bian, X, Wiktor, P, Kahn, P, Khela , A, Karthikeyan, K, Barker, K, Yu, X, Magee, M, Wasserfall, CH, Gibson, David, Rooney, ME, Qiu, J and LaBaer, J (2015) Anti-viral antibody profiling by high density protein arrays.. Proteomics, Tbc. Gibson, David S, Bustard, Michael, McGeough, Cathy, Murray, Helena A, Crockard, Martin A, McDowell, Andrew, Blayney, Jaine, Gardiner, Philip and Bjourson, AJ (2015) Current and future trends in biomarker discovery and development of companion diagnostics for arthritis. Expert Review of Molecular Diagnostics, 15 (2). pp. 219-234. Duncan, Mark W, Gibson, David , Walsh, Ryan, Massod, Afsham and Benabdelkamel, Hicham (2014) An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. In: Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Springer Science, Dordrecht, Germany, pp. 69-81. ISBN 978-94-017-9237-0 Alfadda , AA, Turjoman , AA, Moustafa , AS, Al-Naami , MY, Chishti , MA, Sallam , RM, Gibson, David and Duncan, MW (2014) A proteomic analysis of excreted and circulating proteins from obese patients following two different weight-loss strategies. Exp Biol Med , 239 (5). pp. 568-580. Shyamsundar , M, McAuley , DF, Ingram , RJ, Gibson, David, O'Kane , D, McKeown , ST, Edwards , A, Taggart , C, Elborn , JS, Calfee , CS, Matthay, MA and O'Kane , CM (2014) Keratinocyte Growth-Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury. Am J Respir Crit Care Med, 189 (12). pp. 1520-1529. Ball, EM, Gibson, David, Bell, AL and Rooney, MR (2014) Plasma IL-6 levels correlate with clinical and ultrasound measures of arthritis in patients with systemic lupus erythematosus.. Lupus, 23 (1). pp. 45-56. Finnegan, S, Robson, J, Scaife, C, McAllister, C, Pennington, SR, Gibson, David and Rooney, ME (2014) Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease. Arthritis Research and Therapy, 16 (1). pp. R8. Duncan, Mark and Gibson, David (2012) Mass Spectrometry for Peptide and Protein Analysis. In: Encyclopedia of Analytical Chemistry. John Wiley & Sons, Ltd., Encyclopedia of Analytical Chemistry, pp. 1-22. ISBN ISBN: 9780470027318 Pattison, Sally, Johnston, E, Gibson, David, Pappin , D and Elborn, JS (2012) Proteomic analysis of the chronically infected CF airways. In: 35th European Cystic Fibrosis Conference, Dublin, Ireland. Elsevier B.V.. Gibson, David, Newell, Keri, Evans, Alexandra, Finnegan, Sorcha, Manning, Gwen, Scaife, Caitiona, McAllister, Catherine, Pennington, Stephen, Duncan, Mark, Moore, Terry and Rooney, Madeleine (2012) Vitamin D binding protein isoforms as candidate predictors of disease extension in childhood arthritis. Journal of Proteomics, 75. pp. 5479-5492. Gibson, David, Rooney, Madeleine, Finnegan, Sorcha, Qiu, Ji, Thompson, David, LaBaer, Joshua, Pennington, Stephen and Duncan, Mark (2012) Biomarkers in rheumatology, now and in the future. Rheumatology (Oxford), 51. pp. 423-433. Gibson, David and Jordan, Grant (2012) AN INVESTIGATION INTO THE USE OF HUMAN BONE MARROW OSTEOGENIC CELLS IN THE TREATMENT OF BONE DEFECTS. In: British Orthopaedic Research Society (BORS), Cardiff, Wales, 12 - 13 July 2010. BRITISH EDITORIAL SOCIETY OF BONE AND JOINT SURGERY . Finnegan, Sorcha, Clarke, Susan, Gibson, David, McAllister, Catherine and Rooney, Madeleine (2011) Synovial membrane immunohistology in early untreated juvenile idiopathic arthritis: differences between clinical subgroups. Annals of the Rheumatic Diseases, 70. pp. 1842-1850. Duncan, MW and Gibson, David (2011) Intact Protein Quantification by Mass Spectrometry . In: Mass Spectrometry Applications to the Clinical Lab, San Diego, CA, USA. MSACL, Inc. 281-282
Dr David Gibson
Dr David S. Gibson
Dr David S. Gibson firstname.lastname@example.org
Dr David S. Gibson
Dr David Gibson
Lecturer in Stratified Medicine Biomedical Sciences Research Institute