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Wrong Claire Scanlan?

Claire Scanlan

Process Development Scientist

Millipore Corporation

HQ Phone:  (978) 715-4321

Direct Phone: (781) ***-****direct phone

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I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Community Edition at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

Millipore Corporation

290 Concord Rd.

Billerica, Massachusetts,01821

United States

Company Description

Millipore (NYSE: MIL) is a Life Science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world's challenging human...more

Background Information

Employment History

Process Development Scientist

Merck KGaA


Web References(3 Total References)


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About Claire Scanlan
Claire Scanlan is a process development scientist at EMD Millipore's Biomanufacturing Science Network January 9, 2015 | Claire Scanlan | Mireille Deschamps | Juan Castano | Ruta Waghmare, PhD | Corresponding Author Ruta Waghmare , PhD | ruta.waghmare@emdmillipore.com | doi: 10.14229/jadc.2015.1.9.001


www.biopharma-reporter.com

Despite limitations, particularly for commercial-scale production, single-use systems are being adopted by the biopharmaceutical sector according to Claire Scanlan, a process development scientist at EMD Millipore, who told delegates at AAPS in San Diego that manufacturers are attracted by the flexibility, efficiency and lower cost of such technologies.
Scanlan said that, for a titre of five to six grams per litre, it costs $172 to make a gram of monoclonal antibody (mAb) using a disposable system and $225 to produce the same about in a stainless steel bioreactor. The upfront investment for single-use is also much lower according to Scanlan, who said such systems cost around $25,000 less than steel, at $76,000. She added that nowadays, 5g/l titre and a 70% yield is the standard meaning to make 100kg of a mAb takes 15 runs using a 2,000L disposable bioreactor, whereas in the 1990s it took a similar amount of runs but using a 10,000L (stainless steel) system. "Production and expression levels have doubled every one and a half years over the past 20 years," Scanlan said. Despite this, Scanlan said the results of a study from prepacked column vendor Repligen showed the benefits using prepacked disposable columns.


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About Claire Scanlan
Claire Scanlan is a process development scientist at EMD Millipore's Biomanufacturing Science Network June 6, 2014 | Claire Scanlan, Elina Gousseinov, Alejandro Becerra-Artega, Ph.D, Ruta Waghmare, Ph.D | Corresponding Author Ruta Waghmare, Ph.D; ruta.waghmare@emdmillipore.com | doi: 10.14229/jadc.2014.6.6.001


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