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This profile was last updated on 6/5/15  and contains information from public web pages and contributions from the ZoomInfo community.

Dr. Burton M. Altura

Wrong Dr. Burton M. Altura?

Phone: (718) ***-****  HQ Phone
Email: b***@***.edu
Local Address:  New York , United States
Downstate Medical Center
450 Clarkson Ave. Box 18
Brooklyn , New York 11203
United States


Employment History


  • M.D.
  • Ph.D.
  • PhD
58 Total References
Web References
Burton M. Altura, ..., 11 Sept 2015 [cached]
Burton M. Altura, PhD
Professor of Physiology, Pharmacology & Medicine State University of New York- Downstate Medical Center 450 Clarkson Ave., MSC-31 Brooklyn, NY 11203, USA
Dr. Altura is a Professor at Suny Downstate Medical Center in USA. He received his PhD from Newyork University School of Medicine in the year 1964. He serves as an Ad Hoc Reviewer and also reviewer for various journals and funding organizations.
"It's startling; we're in pretty bad ..., 31 Mar 2015 [cached]
"It's startling; we're in pretty bad shape," says Burton M. Altura, PhD, a professor of physiology and pharmacology at SUNY Downstate Medical Center in Brooklyn, NY. "We have a gigantic deficit."
Altura has helped lead peer-reviewed research that has resulted in more than 1,000 publications in prestigious scientific and medical journals, including five articles in the journal Science. He's also been interviewed by national and international publications, as well as radio and TV stations, and he's helping launch a new group of scientists and physicians called the Magnesium for Health Foundation. Altura and his wife, Dr. Bella T. Altura (a research professor of physiology and pharmacology), have been named honorary co-presidents.
Migraines, 1 Sept 2005 [cached]
"I use the term victim when I refer to chronic headache sufferers, because it's a very wicked syndrome," says Burton M. Altura, M.D., professor of physiology and medicine at the State University of New York Health Science Center at Brooklyn.
They're simply not treating the cause," says Dr. Altura.
In fact, Dr. Altura says that one of his magnesium studies was rejected by a prominent medical journal at the suggestion of a top headache researcher. (Shortly thereafter, the study was published by another journal.) But the weight of evidence for magnesium's use in the treatment of migraines is building.
Too much serotonin can cause blood flow to slow; too little can cause blood to move through too rapidly, explains Dr. Altura.
While mainstream researchers have long known that changes in serotonin and catecholamine levels cause migraine pain, stopping these changes has been a hit-or-miss proposition, says Dr. Altura. An aspirin, for example, temporarily inhibits the effects of serotonin but does nothing to prevent a migraine from coming back, he says.
Dr. Altura says he's the first to prove that loss of magnesium from the brain is behind the problem. Without enough magnesium, serotonin flows unchecked, constricting blood vessels and releasing other pain-producing chemicals such as substance P and prostaglandins, he says. Normal magnesium levels not only prevent the release of these pain-producing substances but also stop their effects, says Dr. Altura.
According to his records, Dr. Altura says that about 50 to 60 percent of his migraine patients have low magnesium levels. But once they begin treatment, he says, they often experience immediate relief. "We can say that 85 to 90 percent of these patients are successfully treated, and that's pretty miraculous," says Dr. Altura.
So can getting more than your share of magnesium every day prevent migraines? Dr. Altura says it's still unclear. "I'd like to be able to answer that question. I can't at this point, but my guess is that it would," he says.
In fact, says Dr. Altura, people who have low magnesium and elevated calcium levels are among those who are most successfully treated with magnesium.
Science News, 15 July 2004 [cached]
Some 350 different enzymes rely on magnesium, notes cardiovascular biologist Burton M. Altura of the State University of New York Health Science Center at Brooklyn.That's more uses than the body makes of any other metal, he observes.
Because some studies had identified an apparent magnesium deficiency in the brains of persons suffering from migraines,both during headaches and between attacks,Altura's group investigated whether rapid infusions of large amounts of the mineral might ameliorate pain.
Subsequent studies of additional migraine patients have confirmed a common pattern, Altura says.
Diet also fails to predict who will tend to have low ionized magnesium concentrations in blood and tissues, Altura has found.In a study 4 years ago, he and his colleagues recruited 18 healthy young men to take different magnesium supplements for 6 days at a time.Although the volunteers had started the trial with normal total-magnesium concentrations,suggesting their diet had contained the RDA of this mineral,a number of the men still had below normal concentrations of the mineral's ionized form.However, once these men were placed on diets containing four to five times the RDA of the mineral, the proportion of ionized magnesium in their blood climbed into the healthy range,despite no change in total magnesium concentrations.
grainWhat all this suggests, Altura says, is that whether someone is deficient in the biologically active form of the mineral may not be detectable through measures of total magnesium.Indeed, his data on cardiac cells indicate that if the concentrations of ionized magnesium falls 25 to 40 percent below normal,irrespective of the total amount of magnesium present,magnesium-dependent enzymes no longer function properly.
Altura, B.T., ... and B.M. Altura.
Burton M. AlturaBox 31State University of New York Health Science Center450 Clarkson AvenueBrooklyn, NY 11203 : Thoughtful Health News, 10 Oct 2000 [cached]
Not so easy , explains Burton Altura , Ph.D. , professor of pharmacology , physiology , and medicine at the State University of New York Health Science Center in Brooklyn.It was Dr. Altura's 20-year body of work on magnesium that initially helped convince Dr. Mauskop of its potential in headache treatment.
Instead , the measurement that counts is ionized magnesium , says Dr. Altura.He's found that 80-90% of migraine sufferers who have low ionized magnesium experience significant relief from intravenous magnesium ( which is readily available to physicians ).
Those 80 to 90% can be headache free not only for 24 hours , but for several months , he asserts.Interestingly , only 40-60% of people who have cluster headaches and low ionized magnesium respond that well , so in both categories , we have responders and nonresponders , but many more responders among those with migraine and chronic migraine , he says.
For 14 years , Dr. Altura and his SUNY research partner ( and wife ) , Bella Altura , Ph.D. , have been helping to design a test for ionized magnesium that could become standard.Currently , one of the few laboratories equipped to measure ionized magnesium on a large scale is Nova Biomedical in Waltham , Massachusetts.
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