About | Free Trial

Last Update

2009-02-15T00:00:00.000Z

This profile was last updated on // .

Is this you? Claim your profile.

Wrong Brian Issell?

Dr. Brian Issell F. MD

Director of the Clinical Trials Unit

Cancer Research Center of Hawaii

Direct Phone: (808) ***-****       

Cancer Research Center of Hawaii

Location Of CRCH On Lauhala Street Clinical Trials Unit 1236 Lauhala Street, Suite 402

Honolulu, Hawaii 96813

United States

Company Description

The Cancer Research Center of Hawai'i maintains a highly productive, externally supported cancer research program. The papers selected here represent some of the highlights of our recent publications from across all disciplines. Please visit the individua ... more

Find other employees at this company (47)

Background Information

Employment History

Center Associate Director of Clinical Sciences and Translational
University of Hawaii

Medical Director, Academic Affairs
Scripps Memorial Hospital

Associate Center Director of Clinical and Translational Research
University of Hawaii Cancer Center

Education

MD

Web References (194 Total References)


Noni Shows Cancer Promise

www.irishnature.com [cached]

Who: Dr. Brian F. Issell, director of the Clinical Trials Unit at the Cancer Research Center of Hawaii

...
Dr. Brian Issell, internist, oncologist and clinical sciences program director at the University of Hawaii cancer center, is principal investigator of the study, which began in 2001.
The noni plant was used in traditional healing throughout Polynesia and is being promoted worldwide for all kinds of health problems and diseases.
"It's a $2 billion product with incredible commercialization," Issell said. "We need to know if it helps more than harms people."
His study is the first to look at the effects of noni on people and see if it does what ads claim.
"We've seen pretty much improvements across the board when we look statistically, but these are early days," Issell said. "It's not telling us it's going to help more than harm people, but what dose we will test in the future."
The team, including Faith Inoshita, clinical research nurse, is trying to complete the first phase of the study to find the right dose that will be effective for people, Issell said.
...
"We have been seeing increasing improvement in quality of life measures," Issell said. "It's very interesting.
...
"We're measuring different markers," Issell said. "Once we have something we can feel confident about, we will use it to standardize noni because there are hundreds of different products now from juice, with additional things to mask the dose."
Noni Maui is providing fruit grown on the Big Island for the study, which requires a consistent supply, Issell said: "We have quite a lot of capsules and will continue up to 40 (per day) if we need to."
...
The first phase of the study began with National Institutes of Health funding and it is continuing with support from the Hawaii Community Foundation, Issell said.
He said the issue with cancer drugs is to find the maximum tolerated dose that's most likely to have an anti-cancer effect.
"Here, we haven't found the maximum-tolerated dose," he said.
...
Issell gets inquiries about noni from all over the world, Gotay pointed out: "That's partly why we are so cautious.


Brian F. Issell, M.D.

www.crch.org [cached]

Brian Issell

...
Brian F. Issell, M.D.Professor (Researcher), Cancer Research Center of Hawaii;Professor of Medicine, John A. Burns School of Medicine
...
Dr. Issell's personal research is directed towards discovering better ways to treat and rehabilitate cancer patients.His most recent work focuses on developing a Complementary and Alternative Medicine initiative that evaluates traditional practices of Hawaii's multicultural population including the use of botanicals for the control of cancer and its related symptoms.He is conducting a Phase I study of Noni that is supported by a National Institutes of Health R21 grant as a first step in the initiative.A recently completed RO1-supported project prospectively examined treatment patterns for women diagnosed with breast cancer in an effort to understand why certain ethnic groups such as Native Hawaiians and Filipinos experience a worse survival.
Administratively, Dr. Issell directs the Cancer Research Center's Clinical Trials Unit.He is principal investigator of the National Cancer Institute - supported, Cancer Information Service of Hawaii and the Hawaii Minority - Based Community Clinical Oncology Program for conducting clinical trials.As a practicing medical oncologist, Dr. Issell is a teaching attending on the Queen Emma Clinics Service at the Queens Medical Center.
Selected Publications
Matsunaga, D.S.; Enos, R.; Gotay, C.C.; Banner, R.O.; DeCambra, H.; Hammond, O.W.; Hedlund, N.; Ilaban, E.K.; Issell, B.F.; Tsark, J.A. Participatory Research in a Native Hawaiian Community: The Waianae Cancer Research Project.Cancer, 78: 1582-1586, 1996.
...
Issell, B. F., Maskarinec, G., Pagano, I., Gotay, C. C. Breast Cancer Treatment among Women of Different Ethnicity in Hawaii.Cancer Investigation , In Press, 2004.


CRCH Site Map

www.crch.org [cached]

Principal Investigator: Brian F. Issell, M.D.


Brian Issell, M.D.

www.crch.org [cached]

Brian F. Issell, M.D. Professor (Researcher), Cancer Research Center of Hawaii; Professor of Medicine, John A. Burns School of Medicine

...
Dr. Issell's personal research is directed towards discovering better ways to treat and rehabilitate cancer patients. His most recent work focuses on developing a Complementary and Alternative Medicine initiative that evaluates traditional practices of Hawaii's multicultural population including the use of botanicals for the control of cancer and its related symptoms. He is conducting a Phase I study of Noni that is supported by a National Institutes of Health R21 grant as a first step in the initiative. A recently completed RO1-supported project prospectively examined treatment patterns for women diagnosed with breast cancer in an effort to understand why certain ethnic groups such as Native Hawaiians and Filipinos experience a worse survival. Administratively, Dr. Issell directs the Cancer Research Center's Clinical Trials Unit. He is principal investigator of the National Cancer Institute - supported, Cancer Information Service of Hawaii and the Hawaii Minority - Based Community Clinical Oncology Program for conducting clinical trials. As a practicing medical oncologist, Dr. Issell is a teaching attending on the Queen Emma Clinics Service at the Queens Medical Center.
Selected Publications Matsunaga, D.S.; Enos, R.; Gotay, C.C.; Banner, R.O.; DeCambra, H.; Hammond, O.W.; Hedlund, N.; Ilaban, E.K.; Issell, B.F.; Tsark, J.A. Participatory Research in a Native Hawaiian Community: The Waianae Cancer Research Project. Cancer, 78: 1582-1586, 1996. Rinehart, J.; Hersch, E.; Issell, B.F.; Triozzi, P.; Buhles, W.: Phase I Trial of Recombinant Human Interleukin 1(Rh 1L-1), Carboplatin and Etoposide in Patients with Solid Cancers, Cancer Investigation 5: 403-410. 1997. Gotay, C.C.; Hara, W; Issell, B.F.; Maskarinec, G.: Use of Complementary and Alternative Medicine in Hawaii Cancer Patients: Hawaii Medical Journal, 58: 94-98, 1999. Gotay, C.C.: Banner, R.O.; Matsunaga, D.S.;Hedlund, N.; Enos, R.;Issell, B.F.; De Cambra, H.: Impact of a Culturally Appropriate Intervention on Breast and Cervical Screening among Native Hawaiian Women, Preventive Medicine 31, 529-537, 2000. Maskarinec G, Pagano I, Yamashiro G, Issell BF.: Influences of Ethnicity, Treatment, and Comorbidity on Breast Cancer Survival. Journal of Clinical Epidemiology 56, 678-685, 2003. Issell, B. F., Maskarinec, G., Pagano, I., Gotay, C. C. Breast Cancer Treatment among Women of Different Ethnicity in Hawaii. Cancer Investigation , In Press, 2004.


CRCH Site Map

www.crch.org [cached]

Principal Investigator: Brian F. Issell, M.D.

Similar Profiles

Other People with this Name

Other people with the name Issell

Sheila Issell
Auslan Connections

Matthew Issell
Super A-Mart Pty Ltd

Natasha Issell
ARC Plastic Surgery

Hagen Issell
NZTC International

Karen Issell

Browse ZoomInfo's Business Contact Directory by City

Browse ZoomInfo's
Business People Directory

Browse ZoomInfo's
Advanced Company Directory