Brian T. Gold, PhD, University of Kentucky
The third speaker of the afternoon was Brian T. Gold, PhD, an Associate Professor in the Department of Anatomy and Neurobiology at the University of Kentucky (UK) College of Medicine.
Dr. Gold is the Director of the Cognitive Neuroscience Laboratory at UK.
research focuses on characterizing cognitive and brain changes associated with normal aging, early Alzheimer's disease (AD), and preclinical AD.
In addition, Dr. Gold
is investigating how certain lifestyle variables (e.g. exercise, education) may slow cognitive decline and brain aging.
A multimodal imaging approach is employed, making use of functional magnetic resonance imaging and structural imaging methods such as volumetric assessment and diffusion tensor imaging.
The title of Dr. Gold's
presentation was White matter microstructural Alterations: Relation to Other Markers of Preclinical Alzheimer's Disease.
The average lifespan following diagnosis of AD is 8 years.
We need better biomarkers.
Mild AD is too late for intervention therapies.
showed pictures on diffusion tensor imaging (DTI).
Different diffusion patterns indicative of different types of damage in the brain.
uses DTI to study connections between different areas of the brain, correlate with clinical data.
presentation is complex; lots of acronyms, a number of regional brain areas.