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Wrong Antonin Holy?

Antonin Holy

Chairman

Institute of Organic Chemistry and Biochemistry

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I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Community Edition at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

Institute of Organic Chemistry and Biochemistry

Web References(29 Total References)


Patents and profits: A disparity of manufacturing margins in the Tenofovir value chain

sacemaquarterly.com [cached]

The discovery of Tenofovir arose from the work of Professor Antonín Holý of the Institute of Organic Chemistry and Biochemistry in Prague, Czech Republic, on a family of nucleosides known as acyclic nucleoside phosphonates, which were found to be excellent reverse transcriptase inhibitors.
Realising their drug potential, Professor Holý established a partnership with Professor Erik de Clercq of the Rega Institute for Medical Research in Leuven, Belgium, who assessed the compounds' antiviral activity (2).


www.gilead.com

Gilead Sciences and the Institute of Organic Chemistry and Biochemistry (IOCB) Establish New Academic Research Centre in Prague; Donation by Gilead Honors Leadership of Dr. Antonin Holy in Antiviral Drug Discovery and Development
Gilead Sciences and the Institute of Organic Chemistry and Biochemistry (IOCB) Establish New Academic Research Centre in Prague; Donation by Gilead Honors Leadership of Dr. Antonin Holy in Antiviral Drug Discovery and Development | Gilead Gilead Gilead Sciences and the Institute of Organic Chemistry and Biochemistry (IOCB) Establish New Academic Research Centre in Prague; Donation by Gilead Honors Leadership of Dr. Antonin Holy in Antiviral Drug Discovery and Development The information in this section is intended for visitors outside the United States. Gilead Sciences and the Institute of Organic Chemistry and Biochemistry (IOCB) Establish New Academic Research Centre in Prague; Donation by Gilead Honors Leadership of Dr. Antonin Holy in Antiviral Drug Discovery and Development Dr. Antonin Holy, IOCB, will be the first to hold the position of Distinguished Chair and will continue to lead research efforts in nucleoside and nucleotide drug discovery. The operation of the Research Centre will be governed by a Steering Committee and monitored by an Advisory Board. In 1991 and 1992, Gilead entered into license agreements with IOCB and the Rega Institute for Medical Research, Katholic University in Leuven, Belgium that cover a large number of nucleotide analogue compounds and structures. Several of these nucleotide compounds (specifically HPMPC, PMPA and PMEA) discovered through a collaborative research effort between Dr. Antonin Holy and Dr. Erik DeClercq, Rega Institute, were developed by Gilead, resulting in Vistide(R) (cidofovir injection) for the treatment of CMV retinitis in AIDS patients, Viread(R) (tenofovir disoproxil fumarate) for the treatment of HIV infection and Hepsera(R) (adefovir dipivoxil) for the treatment of chronic hepatitis B. "We are pleased to be able to honor the contribution of Dr. Holy and the productive collaboration between Gilead and IOCB over the years through this donation, which will fuel IOCB's leading role in scientific research and drug discovery." "The scientific pursuit of new targets, new compounds and novel mechanisms for identifying or treating diseases is our most important priority," said Dr. Antonin Holy.


Gilead Access Program - Welcome

www.gileadaccess.org [cached]

The parent compound of Viread, tenofovir, was discovered through a collaborative research effort between Dr. Antonin Holy, Institute for Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (IOCB) in Prague, and Dr. Erik DeClercq, Rega Institute for Medical Research, Katholic University in Leuven, Belgium.


Gilead -- Patient Care

www.gilead.com [cached]

The parent compound of Viread, tenofovir, was discovered through a collaborative research effort between Dr. Antonin Holy, Institute for Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (IOCB) in Prague and Dr. Erik DeClercq, Rega Institute for Medical Research, Katholic University in Leuven, Belgium.


Designer Drugs For HIV (October 2006)

www.amfar.org [cached]

Dr. Antonin Holy of the Institute of Organic Chemistry and Biochemistry in Prague, Czech Republic, writing in the journal Antiviral Research, reviews the work of his group and others on the modification of NRTI-like drugs, opening their closed ring structures, adding on chemical groups to alter their electric charge and increase their ability to enter cells, and so on.


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