Donation by Gilead Honors Leadership of Dr. Antonin Holy in Antiviral Drug Discovery and Development
Foster City, CA & Prague, Czech Republic - Gilead Sciences, Inc.
announced a donation to The Institute of Organic Chemistry and Biochemistry at the Academy of Sciences of the Czech Republic
(IOCB) for the establishment of a Gilead Sciences Research Centre
will provide a $1.1 million annual donation to IOCB
for an initial five-year term to fund the Centre's operations and ongoing research activities. IOCB
will use the donations to establish and support the Gilead Sciences Research Centre
, which will consist of selected research groups led by the scientists at IOCB
.In addition, Gilead
will establish the Gilead Distinguished Chair in Medicinal Chemistry.Dr. Antonin Holy, IOCB, will be the first to hold the position of Distinguished Chair and will continue to lead research efforts in nucleoside and nucleotide drug discovery.
The operation of the Research Centre will be governed by a Steering Committee and monitored by an Advisory Board.
In 1991 and 1992, Gilead
entered into license agreements with IOCB
and the Rega Institute for Medical Research
, Katholic University
in Leuven, Belgium that cover a large number of nucleotide analogue compounds and structures.Several of these nucleotide compounds (specifically HPMPC, PMPA and PMEA) discovered through a collaborative research effort between Dr. Antonin Holy
and Dr. Erik DeClercq, Rega Institute
, were developed by Gilead
, resulting in Vistide(R) (cidofovir injection) for the treatment of CMV retinitis in AIDS patients, Viread(R) (tenofovir disoproxil fumarate) for the treatment of HIV infection and Hepsera(R) (adefovir dipivoxil) for the treatment of chronic hepatitis B.
"We are pleased to be able to honor the contribution of Dr. Holy
and the productive collaboration between Gilead and IOCB
over the years through this donation, which will fuel IOCB's leading role in scientific research and drug discovery."
"The scientific pursuit of new targets, new compounds and novel mechanisms for identifying or treating diseases is our most important priority," said Dr. Antonin Holy