No Photo Available

Last Update

2016-09-28T00:00:00.000Z

This profile was last updated on .

Is this you? Claim your profile.

Wrong Alfredo Galvez?

Dr. Alfredo F. Galvez

Research Geneticist

USDA

Get ZoomInfo Grow

+ Get 10 Free Contacts a Month

Please agree to the terms and conditions

I agree to the Terms of Service and Privacy Policy. I understand that I will receive a subscription to ZoomInfo Grow at no charge in exchange for downloading and installing the ZoomInfo Contact Contributor utility which, among other features, involves sharing my business contacts as well as headers and signature blocks from emails that I receive.

USDA

Background Information

Employment History

Postdoctoral Researcher

Berkeley

Chief Scientific Officer

Missouri Plant Science Center

Director of Research

Missouri Plant Science Center

Adjunct Assistant Professor

University of Missouri

Affiliations

Lead Scientific Advisor
Soy Labs LLC

Chief Scientific Officer
SL Technology

Center Scientist (Collaborator)
UC Davis

Lead Scientific Advisor
Missouri Plant Science Center

Lead Scientific Advisor
The MPSC

Lead Scientific Advisor
Mexico Public Schools

Lead Scientific Advisor
MPSC’s

Education

University of the Philippines

B.S.

Genetics and Plant Physiology

University of the Philippines at Los Banos

M.S. degrees

Genetics and Plant Physiology

University of the Philippines at Los Banos

Ph.D.

University of California at Davis Center of Excellence for Nutritional Genomics & University of Missouri at Columbia

Ph.D.

Washington State University

Ph.D.

Genetics

University of California , Davis

PhD

Genetics and Molecular Biology

UC Davis

doctorate

genetics

University of California Davis

Web References (51 Total References)


Alfredo F. Galvez, ...

lunasin.com [cached]

Alfredo F. Galvez, Ph.D.

Project Scientist, Center of Excellence for Nutritional Genomics, University of California, Davis, CA Chief Scientific Officer, SL Technology, Inc., Chesterfield, MO
Alfredo F. Galvez, Ph.D. is currently the Chief Scientific Officer of SL Tech, Inc., a Reliv subsidiary company, working on the development of functional foods and nutraceutical ingredients based on the lunasin peptide, a soy protein component he serendipitously discovered in 1996 as a postdoctoral researcher at UC Berkeley. He has a PhD in Genetics from UC Davis, majoring in molecular biology and cytogenetics. He is also a Project Scientist at the Center for Nutritional Genomics, University of California at Davis, working on elucidating the molecular mechanism of lunasin as a peptidomimetic of a human tumor suppressor.
Dr. Galvez earned his B.S. and M.S. degrees in Genetics and Plant Physiology from the University of the Philippines at Los Banos, and his Ph.D. in Genetics from the University of California, Davis. After completing his Ph.D., Dr. Galvez worked for the USDA-ARS at Washington State University and at the University of California Berkeley as a Research Biochemist and Geneticist.


December 2013 Newsletter | Filipino Community Center

filcom.org [cached]

Dr. Alfredo Galvez

Dr. Alfredo Galvez, a graduate of the University of the Philippines in Los Banos, will be conducting another freeseminar on December 14, Saturday at 9:30 a.m. at the FilCom Center in Waipahu to reprise a workshop he conducted last September. He will discuss again the potentially life-altering effects of Lunasin and its effects on cancer as well as other serious health issues.
Dr. Galvez grew up in La Union, Philippines with an inherent love for science and a built-in desire to experiment with plants. Galvez graduated from the UP Los Banos with a Masters in Genetics and Plant Breeding. He received a scholarship to UC Davis where he pursued his PhD in Genetics and Molecular Biology. He went on to become a Research Geneticist at the USDA in Washington State University where he had been for two years when a colleague from UP Los Banos asked his help in gene cloning at UC Berkeley. After joining their staff a serendipitous discovery was made. As an accidental by-product of their cloning work, Lunasin was discovered. Lunasin is an extraordinary plant peptide that has been shown to disrupt cancer cell division and prevent tumor formation. Galvez and his colleagues named it Lunasin which is the Tagalog word for "heal" or "remedy".
...
Dr. Galvez is proving that this is not true. Though we cannot change our DNA, Lunasin has the ability to essentially turn "off" the bad genes and turn "on" the good genes in our bodies. This is a game changer in the area of disease control as well as many other areas.
In his research, Dr. Galvez realized that this impressive natural peptide, found in miniscule quantities in soybeans, blocks cell division and effectively turns down the dimmer switch in our genetic material. In other words, it makes cells less receptive to disease. This mechanism has been included in prestigious journals such as theJournal of Cancer Research. Further, a recent analysis in Cancer Metastasis Reviews noted that lunasin has been shown to be active against human breast cancer, colon cancer, and leukemia cells in the laboratory. In a mouse study, injection of lunasin into mice implanted with human breast cancer cells reduced tumor incidence by 33 to 49 percent.
Dr. Galvez also discovered that it is not Lunasin alone that refocuses our genetic material. He is making history because he developed a means of protecting the peptide so that sufficient amounts could be absorbed once inside the body. "I have been excited for years about the enormous potential of the Lunasin peptide, says Galvez, but it's the bioactive Lunasin, that has opened the door to a broad range of dramatic health benefits and I am helping the world with affordable solutions."
Dr. Galvez is presently a Research Scientist at the Center of Excellence for Nutritional Genomics, UC Davis, California. He is also the Director of Research for the Missouri Plant Science Center, Mexico, MO.


Scientist Bios

www.lunasin.com [cached]

Dr. Alfredo Galvez's presentation abstract was selected for publication in the prestigious AHA Journal, Circulation! View the abstract here.

...
Alfredo F. Galvez, Ph.D Center Scientist, Center of Excellence for Nutritional Genomics, University of California, Davis, CA
...
Dr. Alfredo Galvez joined the Center of Excellence in Nutritional Genomics six years ago to work on elucidating the molecular mechanism of action of the soy peptide, lunasin. Dr. Galvez serendipitously discovered the anti-cancer properties of the lunasin peptide, while working as a postdoctoral researcher on a project to increase the methionine content of soy protein at UC Berkeley in the late 1990's. His work led to the novel finding that lunasin binds specifically to deacetylated histones H3 and H4 and prevents their acetylation via a masking effect. Inhibitors of histone acetylation are correlated with gene repression, however microarray analysis of prostate cells treated with lunasin under basal condition showed that this soy peptide upregulates expression of chemopreventive genes but only in the non-tumorigenic cell line. The current working model to explain the microarray results is that lunasin preferentially binds to deacetylated lysine 8 in histone H4 and increases acetylation of H4-lysine 16, leading to increased gene expression.
Dr. Galvez continues to work with the University of Missouri to further demonstrate Lunasin's effect on LDL cholesterol. This is based on his discovery that lunasin can inhibit the acetylation of histone H3 by the PCAF histone acetylase enzyme and reduce expression of HMG-CoA reductase (the rate-limiting enzyme for cholesterol biosynthesis) in liver cells. Chromatin immunoprecipitation (ChIP) have shown that SREBP transcriptional activation of HMG-CoA reductase requires H3 acetylation by PCAF. This discovery provides a mechanism of action to explain the cholesterol-lowering effects of soy protein and paves the way for optimizing soy protein ingredients to maximize its heart-healthy benefits.
Prior to joining the Center, Dr. Galvez has founded and worked in a start-up biotech company. He obtained his Ph.D. in Genetics from UC Davis in 1992 and has worked as a research scientist for the USDA and UC Berkeley.


Alfredo F. Galvez, ...

www.lunasin.com [cached]

Alfredo F. Galvez, Ph.D.

...
Alfredo F. Galvez, Ph.D.
Center Scientist, Center of Excellence for Nutritional Genomics, University of California, Davis, CA Adjunct Assistant Professor, University of Missouri, Columbia, MO Lead Scientific Advisor, Soy Labs, LLC, Fairfield, CA
Dr. Alfredo Galvez joined the Center of Excellence in Nutritional Genomics two years ago to work on elucidating the molecular mechanism of action of the soy peptide, lunasin. Dr. Galvez serendipitously discovered the anti-cancer properties of the lunasin peptide, while working as a postdoctoral researcher on a project to increase the methionine content of soy protein at UC Berkeley in the late 1990's. His work led to the novel finding that lunasin binds specifically to deacetylated histones H3 and H4 and prevents their acetylation via a masking effect. Inhibitors of histone acetylation are correlated with gene repression, however microarray analysis of prostate cells treated with lunasin under basal condition showed that this soy peptide upregulates expression of chemopreventive genes but only in the non-tumorigenic cell line. The current working model to explain the microarray results is that lunasin preferrentially binds to deacetylated lysine 8 in histone H4 and increases acetylation of H4-lysine 16, leading to increased gene expression.
Dr. Galvez is also collaborating with the Missouri Soybean Board, Soy Labs and the University of Missouri to develop cholesterol-lowering soy protein extracts for commercial production. This is based on his discovery that lunasin can inhibit the acetylation of histone H3 by the PCAF histone acetylase enzyme and reduce expression of HMG-CoA reductase (the rate-limiting enzyme for cholesterol biosynthesis) in liver cells. Chromatin immunoprecipitation (ChIP) have shown that SREBP transcriptional activation of HMG-CoA reductase requires H3 acetylation by PCAF. This discovery provides a mechanism of action to explain the cholesterol-lowering effects of soy protein and paves the way for optimizing soy protein ingredients to maximize its heart-healthy benefits.
Prior to joining the Center, Dr. Galvez has founded and worked in a start-up biotech company. He obtained his Ph.D. in Genetics from UC Davis in 1992 and has worked as a research scientist for the USDA and UC Berkeley.
...
Galvez, A.F. , Chen N., Macasieb J. and B.O. de Lumen.
...
Galvez, A.F. and B.O. de Lumen.


Alfredo Galvez, Ph.D., ...

www.supplysideshow.com [cached]

Alfredo Galvez, Ph.D., discovered the anti-cancer properties of the lunasin peptide while working as a postdoctoral researcher on a project to increase the methionine content of soy protein at the University of California Berkeley in the late 1990s.This novel finding is that lunasin binds specifically to deacetylated histones H3 and H4, and prevents their acetylation via a masking effect.Based on his discovery that lunasin can inhibit the acetylation of histone H3 by the PCAF histone acetylase enzyme, and reduce expression of HMG-CoA reductase (the rate-limiting enzyme for cholesterol biosynthesis) in liver cells, he is currently developing cholesterol-lowering soy protein extracts for the natural products industry.Dr. Galvez obtained his doctorate in genetics from the University of California Davis, and has worked as a research scientist for the USDA and UC Berkeley.He also serves as Center Scientist, Center of Excellence for Nutritional Genomics, University of California, Davis; Adjunct Assistant Professor, University of Missouri, Columbia, and is lead scientific advisor at Soy Labs.

Similar Profiles

Other People with this Name

Other people with the name Galvez

John Galvez
Lawrence Tractor Co. Inc

Antonio Galvez
Alpha Technologies , Inc.

Benjamin Galvez
New Community Corporation

Gabriel Galvez
CAPTARGET LLC

Dora Castaneda Galvez
Moores UCSD Cancer Center

City Directory Icon

Browse ZoomInfo's Business Contact Directory by City

People Directory Icon

Browse ZoomInfo's
Business People Directory

Company Directory Icon

Browse ZoomInfo's
Advanced Company Directory